Cambridge University EPIC-Norfolk
   
  EPIC-Norfolk: Publications
(with selected papers relating to the international EPIC study)
 

Notes

For all papers, the button provides a direct link to the relevant journal, where available. The journal website will generally show the abstract.

The button links to a full text version of a paper, if one is available. All of the full text links will work if you have a cam.ac.uk IP address, but some may not work from other institutions. Some of the full text versions are in Adobe Acrobat format.

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Clicking on the button takes you to our page giving futher details of selected papers.
 

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K Khaw, SJ Sharp, L Finikarides, I Afzal, M Lentjes, R Luben, NG Forouhi. (2018) Randomised trial of coconut oil, olive oil or butter on blood lipids and other cardiovascular risk factors in healthy men and women. BMJ Open 8 (3):e020167.

VL Keevil, R Luben, S Hayat, AA Sayer, NJ Wareham, K Khaw. (2018) Physical capability predicts mortality in late mid-life as well as in old age: Findings from a large British cohort study. Arch Gerontol Geriatr 74 ():77-82.

NRV Jones, NG Forouhi, K Khaw, NJ Wareham, P Monsivais. (2018) Accordance to the Dietary Approaches to Stop Hypertension diet pattern and cardiovascular disease in a British, population-based cohort. Eur J Epidemiol 33 (2):235-244.

C Lassale, A Curtis, I Abete, YT van der Schouw, MWM Verschuren, Y Lu, H Bueno-de-Mesquita. (2018) Elements of the complete blood count associated with cardiovascular disease incidence: Findings from the EPIC-NL cohort study. Sci Rep 8 (1):3290.

C Lassale, I Tzoulaki, KGM Moons, M Sweeting, J Boer, L Johnson, J Huerta, C Agnoli, H Freisling, E Weiderpass, P Wennberg, D {van der A}, L Arriola, V Benetou, H Boeing, F Bonnet, SM Colorado-Yohar, G Engstrom, AK Eriksen, P Ferrari, S Grioni, M Johansson, R Kaaks, M Katsoulis, V Katzke, TJ Key, G Matullo, O Melander, E Molina-Portillo, C Moreno-Iribas, M Norberg, Kim Overvad, S Panico, RJ Quiros, C Saieva, G Skeie, A Steffen, M Stepien, A Tjonneland, A Trichopoulou, R Tumino, YT van der Schouw, MWM Verschuren, C Langenberg, E Di Angelantonio, E Riboli, NJ Wareham, J Danesh, AS Butterworth. (2018) Separate and combined associations of obesity and metabolic health with coronary heart disease: a pan-{Europe}an case-cohort analysis. Eur Heart J 39 (5):397-406.

S Lachman, MS Boekholdt, RN Luben, SJ Sharp, S Brage, K Khaw, Ron Peters, NJ Wareham. (2018) Impact of physical activity on the risk of cardiovascular disease in middle-aged and older adults: EPIC Norfolk prospective population study. Eur J Prev Cardiol 25 (2):200-208.

OT Mytton, NG Forouhi, P Scarborough, M Lentjes, R Luben, M Rayner, K Khaw, NJ Wareham, P Monsivais. (2018) Association between intake of less-healthy foods defined by the {United Kingdom}'s nutrient profile model and cardiovascular disease: A population-based cohort study. PLoS Med 15 (1):e1002484.

AA Mulligan, MAH Lentjes, RN Luben, NJ Wareham, K Khaw. (2018) Weight change and 15{~}year mortality: results from the {Europe}an Prospective Investigation into Cancer in Norfolk (EPIC-Norfolk) cohort study. Eur J Epidemiol 33 (1):37-53.

N Perrot, MS Boekholdt, P Mathieu, NJ Wareham, K Khaw, BJ Arsenault. (2018) Life's simple 7 and calcific aortic valve stenosis incidence in apparently healthy men and women. Int J Cardiol ():.

CG Owen, AR Rudnicka, RA Welikala, MM Fraz, SA Barman, R Luben, SA Hayat, K Khaw, DP Strachan, PH Whincup, PJ Foster. (2018) Retinal vasculometry associations with cardiometabolic risk factors in the {Europe}an Prospective Investigation of Cancer Norfolk study. Ophthalmology ():.

C Ricci, A Wood, D Muller, MJ Gunter, A Agudo, H Boeing, YT van der Schouw, S Warnakula, C Saieva, A Spijkerman, I Sluijs, A Tjonneland, C Kyro, E Weiderpass, T Kuhn, R Kaaks, M Sanchez, S Panico, C Agnoli, D Palli, R Tumino, G Engstrom, O Melander, F Bonnet, JMA Boer, TJ Key, RC Travis, Kim Overvad, MWM Verschuren, RJ Quiros, A Trichopoulou, E Papatesta, E Peppa, C Iribas, D Gavrila, A Forslund, J Jansson, G Matullo, L Arriola, H Freisling, C Lassale, I Tzoulaki, SJ Sharp, NG Forouhi, C Langenberg, R Saracci, M Sweeting, P Brennan, AS Butterworth, E Riboli, NJ Wareham, J Danesh, P Ferrari. (2018) Alcohol intake in relation to non-fatal and fatal coronary heart disease and stroke: EPIC-CVD case-cohort study. BMJ 361 ():k934.

AN Samraj, KA Bertrand, R Luben, Z Khedri, Hai Yu, D Nguyen, CJ Gregg, SL Diaz, S Sawyer, Xi Chen, H Eliassen, V Padler-Karavani, K Wu, K Khaw, W Willett, A Varki. (2018) Polyclonal human antibodies against glycans bearing red meat-derived non-human sialic acid N-glycolylneuraminic acid are stable, reproducible, complex and vary between individuals: Total antibody levels are associated with colorectal cancer risk. PLoS One 13 (6):e0197464.

R Verbeek, RM Hoogeveen, A Langsted, LCA Stiekema, SL Verweij, KG Hovingh, NJ Wareham, K Khaw, MS Boekholdt, BG Nordestgaard, ESG Stroes. (2018) Cardiovascular disease risk associated with elevated lipoprotein(a) attenuates at low low-density lipoprotein cholesterol levels in a primary prevention setting. Eur Heart J 39 (27):2589-2596.

AM Wood, S Kaptoge, AS Butterworth, P Willeit, S Warnakula, T Bolton, E Paige, DS Paul, M Sweeting, S Burgess, S Bell, W Astle, D Stevens, A Koulman, RM Selmer, MWM Verschuren, S Sato, I Njolstad, , Woodward, , Salomaa, , Nordestgaard, , Yeap, , Fletcher, , Melander, , Kuller, , Balkau, , Marmot, , Koenig, , Casiglia, , Cooper, , Arndt, , Franco, , Wennberg, , Gallacher, A de-la Camara, , V"olzke, , Dahm, , Dale, , Bergmann, , Crespo, YT Schouw, , Kaaks, , Simons, , Lagiou, , Schoufour, , Boer, , Key, , Rodriguez, , Moreno-Iribas, , Davidson, , Taylor, , Sacerdote, , Wallace, , Quiros, , Tumino, , Blazer, , Linneberg, , Daimon, , Panico, , Howard, , Skeie, , Strandberg, , Weiderpass, , Nietert, , Psaty, , Kromhout, , Salamanca-Fernandez, , Kiechl, , Krumholz, , Grioni, , Palli, , Huerta, , Price, , Sundstr"om, , Arriola, , Arima, , Travis, , Panagiotakos, , Karakatsani, , Trichopoulou, , K"uhn, , Grobbee, , Barrett-Connor, N van-Schoor, , Boeing, , Overvad, , Kauhanen, , Wareham, , Langenberg, , Forouhi, , Wennberg, , Despr\es, , Cushman, , Cooper, , Rodriguez, , Sakurai, , Shaw, , Knuiman, , Voortman, , Meisinger, , Tj\onneland, , Brenner, , Palmieri, , Dallongeville, , Brunner, , Assmann, , Trevisan, , Gillum, , Ford, , Sattar, , Lazo, , Thompson, , Ferrari, , Leon, , Smith, , Peto, , Jackson, , Banks, E Di-Angelantonio, , Danesh, PICCVK . (2018) Risk thresholds for alcohol consumption: combined analysis of individual-participant data for 599912 current drinkers in 83 prospective studies. Lancet 391 (10129):1513-1523.

C Baumgartner, BR da Costa, T Collet, M Feller, C Floriani, DC Bauer, AR Cappola, SR Heckbert, G Ceresini, J Gussekloo, WPJ den Elzen, RP Peeters, R Luben, H Volzke, M Dorr, JP Walsh, A Bremner, M Iacoviello, P Macfarlane, Jan Heeringa, DJ Stott, RGJ Westendorp, K Khaw, JW Magnani, D Aujesky, N Rodondi, T, Collaboration. (2017) Thyroid Function Within the Normal Range, Subclinical Hypothyroidism, and the Risk of Atrial Fibrillation. Circulation 136 (22):2100-2116.

HT Jorstad, SM Boekholdt, NJ Wareham, KT Khaw, RJG Peters. (2017) The Dutch {SC}ORE-based risk charts seriously underestimate the{~}risk of cardiovascular disease. Neth Heart J 25 (3):173-180.

MJ Gunter, N Murphy, AJ Cross, L Dossus, L Dartois, Guy Fagherazzi, R Kaaks, T Kuhn, H Boeing, K Aleksandrova, A Tjonneland, A Olsen, Kim Overvad, S Larsen, M {Redondo Cornejo}, A Agudo, M {S{\{a}}nchez P{\{e}}rez}, JM Altzibar, C Navarro, Eva Ardanaz, K Khaw, A Butterworth, KE Bradbury, A Trichopoulou, P Lagiou, D Trichopoulos, D Palli, S Grioni, P Vineis, S Panico, R Tumino, B Bueno-de-Mesquita, P Siersema, Max Leenders, JWJ Beulens, CU Uiterwaal, P Wallstrom, L Nilsson, R Landberg, E Weiderpass, G Skeie, T Braaten, P Brennan, I Licaj, DC Muller, R Sinha, N Wareham, E Riboli. (2017) Coffee Drinking and Mortality in 10 {Europe}an Countries: A Multinational Cohort Study. Ann Intern Med 167 (4):236-247.

LA Lotta, P Gulati, FR Day, F Payne, H Ongen, M van Bunt, KJ Gaulton, JD Eicher, SJ Sharp, J Luan, E {De Lucia Rolfe}, ID Stewart, E Wheeler, SM Willems, C Adams, H Yaghootkar, Consortium C-InterAct, D Consortium, NG Forouhi, K Khaw, AD Johnson, RK Semple, T Frayling, JRB Perry, E Dermitzakis, MI McCarthy, I Barroso, NJ Wareham, DB Savage, C Langenberg, S ORahilly, RA Scott. (2017) Integrative genomic analysis implicates limited peripheral adipose storage capacity in the pathogenesis of human insulin resistance. Nat Genet 49 (1):17-26.

MAH Lentjes, RH Keogh, AA Welch, AA Mulligan, RN Luben, NJ Wareham, K Khaw. (2017) Longitudinal associations between marine omega-3~{s}upplement users and coronary heart disease in a UK population-based cohort. BMJ Open 7 (10):e017471.

GG Kuhnle, R Luben, K Khaw, M Feelisch. (2017) Sulfate, nitrate and blood pressure - An EPIC interaction between sulfur and nitrogen. Pharmacol Res 122 ():127-129.

DJ Liu, GM Peloso, H Yu, AS Butterworth, X Wang, A Mahajan, D Saleheen, C Emdin, D Alam, A Alves, P Amouyel, E Di Angelantonio, D Arveiler, TL Assimes, PL Auer, U Baber, CM Ballantyne, Lia Bang, M Benn, JC Bis, M Boehnke, E Boerwinkle, J Bork-Jensen, EP Bottinger, I Brandslund, M Brown, F Busonero, MJ Caulfield, JC Chambers, DI Chasman, EY Chen, Y Chen, R Chowdhury, C Christensen, AY Chu, JM Connell, F Cucca, AL Cupples, SM Damrauer, G Davies, Ian Deary, G Dedoussis, JC Denny, A Dominiczak, M Dube, T Ebeling, G Eiriksdottir, T Esko, A Farmaki, MF Feitosa, M Ferrario, J Ferrieres, Ian Ford, M Fornage, PW Franks, TM Frayling, R Frikke-Schmidt, LG Fritsche, P Frossard, V Fuster, SK Ganesh, Wei Gao, ME Garcia, C Gieger, F Giulianini, MO Goodarzi, H Grallert, N Grarup, L Groop, ML Grove, V Gudnason, T Hansen, TB Harris, C Hayward, JN Hirschhorn, OL Holmen, J Huffman, Y Huo, K Hveem, S Jabeen, AU Jackson, J Jakobsdottir, M Jarvelin, GB Jensen, ME Jorgensen, WJ Jukema, JM Justesen, Pia Kamstrup, S Kanoni, F Karpe, F Kee, AV Khera, D Klarin, HA Koistinen, JS Kooner, C Kooperberg, K Kuulasmaa, J Kuusisto, M Laakso, T Lakka, C Langenberg, A Langsted, LJ Launer, T Lauritzen, DCM Liewald, L Lin, A Linneberg, RJF Loos, Y Lu, X Lu, R Magi, A Malarstig, Ani Manichaikul, AK Manning, P Mantyselka, E Marouli, NGD Masca, A Maschio, JB Meigs, O Melander, A Metspalu, AP Morris, AC Morrison, A Mulas, M Muller-Nurasyid, PB Munroe, MJ Neville, JB Nielsen, SF Nielsen, BG Nordestgaard, JM Ordovas, R Mehran, CJ ODonnell, M Orho-Melander, CM Molony, P Muntendam, S Padmanabhan, CNA Palmer, D Pasko, AP Patel, O Pedersen, M Perola, A Peters, C Pisinger, G Pistis, O Polasek, N Poulter, BM Psaty, DJ Rader, A Rasheed, R Rauramaa, DF Reilly, AP Reiner, F Renstrom, SS Rich, PM Ridker, JD Rioux, NR Robertson, Dan Roden, JI Rotter, I Rudan, V Salomaa, NJ Samani, S Sanna, N Sattar, EM Schmidt, RA Scott, P Sever, RS Sevilla, CM Shaffer, X Sim, S Sivapalaratnam, KS Small, AV Smith, BH Smith, S Somayajula, L Southam, TD Spector, EK Speliotes, JM Starr, KE Stirrups, N Stitziel, K Strauch, HM Stringham, P Surendran, H Tada, . (2017) Exome-wide association study of plasma lipids in >300,000 individuals. Nat Genet 49 (12):1758-1766.

N Perrot, R Verbeek, M Sandhu, MS Boekholdt, KG Hovingh, NJ Wareham, K Khaw, BJ Arsenault. (2017) Ideal cardiovascular health influences cardiovascular disease risk associated with high lipoprotein(a) levels and genotype: The EPIC-Norfolk prospective population study. Atherosclerosis 256 ():47-52.

D Saleheen, Wei Zhao, R Young, CP Nelson, W Ho, JF Ferguson, A Rasheed, K Ou, ST Nurnberg, RC Bauer, A Goel, Ron Do, AFR Stewart, J Hartiala, W Zhang, G Thorleifsson, RJ Strawbridge, J Sinisalo, S Kanoni, S Sedaghat, E Marouli, K Kristiansson, J Zhao, R Scott, D Gauguier, SH Shah, A Smith, N van Zuydam, AJ Cox, C Willenborg, T Kessler, L Zeng, MA Province, A Ganna, L Lind, NL Pedersen, CC White, A Joensuu, M Kleber, AS Hall, W Marz, V Salomaa, C ODonnell, E Ingelsson, MF Feitosa, J Erdmann, DW Bowden, CNA Palmer, V Gudnason, Ulf Faire, P Zalloua, N Wareham, JR Thompson, K Kuulasmaa, G Dedoussis, M Perola, A Dehghan, JC Chambers, J Kooner, H Allayee, P Deloukas, R McPherson, K Stefansson, H Schunkert, S Kathiresan, M Farrall, P Frossard, DJ Rader, NJ Samani, MP Reilly. (2017) Loss of Cardioprotective Effects at the ADAMTS7 Locus as a Result of Gene-Smoking Interactions. Circulation 135 (24):2336-2353.

R Verbeek, M Boyer, MS Boekholdt, KG Hovingh, JJP Kastelein, N Wareham, K Khaw, BJ Arsenault. (2017) Carriers of the {PC}SK9 R46L Variant Are Characterized by an Antiatherogenic Lipoprotein Profile Assessed by Nuclear Magnetic Resonance Spectroscopy-Brief Report. Arterioscler Thromb Vasc Biol 37 (1):43-48.

R Verbeek, MS Sandhu, KG Hovingh, B Sjouke, NJ Wareham, AH Zwinderman, JJP Kastelein, K Khaw, S Tsimikas, MS Boekholdt. (2017) Lipoprotein(a) Improves Cardiovascular Risk Prediction{~}Based on Established Risk Algorithms. J Am Coll Cardiol 69 (11):1513-1515.

JC van Capelleveen, SJ Moens, X Yang, JJP Kastelein, NJ Wareham, AH Zwinderman, ESG Stroes, JL Witztum, KG Hovingh, K Khaw, MS Boekholdt, S Tsimikas. (2017) Apolipoprotein C-III Levels and Incident Coronary Artery Disease Risk: The EPIC-Norfolk Prospective Population Study. Arterioscler Thromb Vasc Biol 37 (6):1206-1212.

JC van Capelleveen, AE Bochem, MS Boekholdt, S Mora, Ron Hoogeveen, CM Ballantyne, PM Ridker, W Sun, PJ Barter, AR Tall, AH Zwinderman, JJP Kastelein, NJ Wareham, K Khaw, KG Hovingh. (2017) Association of High-Density Lipoprotein-Cholesterol Versus Apolipoprotein A-I With Risk of Coronary Heart Disease: The {Europe}an Prospective Investigation Into Cancer-Norfolk Prospective Population Study, the Atherosclerosis Risk in Communities Study, and the Women's Health Study. J Am Heart Assoc 6 (8):.

TYN Tong, NJ Wareham, K Khaw, F Imamura, NG Forouhi. (2016) Prospective association of the Mediterranean diet with cardiovascular disease incidence and mortality and its population impact in a non-Mediterranean population: the EPIC-Norfolk study. BMC medicine 14 ():135.

RM Stoekenbroek, MS Boekholdt, R Luben, KG Hovingh, AH Zwinderman, NJ Wareham, K Khaw, Ron Peters. (2016) Heterogeneous impact of classic atherosclerotic risk factors on different arterial territories: the EPIC-Norfolk prospective population study. Eur Heart J 37 (11):880-889.

DF van Wijk, MS Boekholdt, BJ Arsenault, S Ahmadi-Abhari, NJ Wareham, ESG Stroes, K Khaw. (2016) C-Reactive Protein Identifies Low-Risk Metabolically Healthy Obese Persons: The {Europe}an Prospective Investigation of Cancer-Norfolk Prospective Population Study. J Am Heart Assoc 5 (6):.

R Verbeek, MS Boekholdt, RM Stoekenbroek, KG Hovingh, JL Witztum, NJ Wareham, MS Sandhu, K Khaw, S Tsimikas. (2016) Population and assay thresholds for the predictive value of lipoprotein (a) for coronary artery disease: the EPIC-Norfolk Prospective Population Study. Journal of lipid research 57 ():697-705.

P Zanoni, SA Khetarpal, DB Larach, WF Hancock-Cerutti, JS Millar, M Cuchel, S DerOhannessian, A Kontush, P Surendran, D Saleheen, S Trompet, WJ Jukema, A Craen, P Deloukas, N Sattar, Ian Ford, C Packard, A Majumder, DS Alam, E Angelantonio, G Abecasis, R Chowdhury, J Erdmann, BG Nordestgaard, SF Nielsen, A TybjAtextbrokenbarrg-Hansen, R Schmidt, K Kuulasmaa, DJ Liu, M Perola, S Blankenberg, V Salomaa, S MAtextcurrencynnistAP, P Amouyel, D Arveiler, J Ferrieres, M MAsfrac-Nurasyid, M Ferrario, F Kee, CJ Willer, N Samani, H Schunkert, AS Butterworth, JMM Howson, GM Peloso, NO Stitziel, J Danesh, S Kathiresan, DJ Rader, Exome+ CHD, C Consortium, Lipids Global. (2016) Rare variant in scavenger receptor BI raises {HDL} cholesterol and increases risk of coronary heart disease. Science (New York, N.Y.) 351 ():1166-1171.

W Zhang, F JernerAcopyrightn, BC Lehne, M Chen, RN Luben, C Johnston, A Elshorbagy, RN Eppinga, WR Scott, E Adeyeye, J Scott, RH BAPger, K Khaw, Pim van der Harst, NJ Wareham, RS Vasan, JC Chambers, H Refsum, JS Kooner. (2016) Genome-wide association reveals that common genetic variation in the kallikrein-kinin system is associated with serum L-arginine levels. Thrombosis and haemostasis 116 ():1041-1049.

N Basu, X Yang, RN Luben, D Whibley, GJ Macfarlane, NJ Wareham, K Khaw, P Myint. (2016) Fatigue is associated with excess mortality in the general population: results from the EPIC-Norfolk study. BMC medicine 14 ():122.

LC Del Gobbo, F Imamura, S Aslibekyan, M Marklund, JK Virtanen, M Wennberg, MY Yakoob, SE Chiuve, L Dela Cruz, AC Frazier-Wood, AM Fretts, E Guallar, C Matsumoto, K Prem, T Tanaka, JHY Wu, Xia Zhou, C Helmer, E Ingelsson, J Yuan, P Barberger-Gateau, H Campos, PHM Chaves, Luc DjoussAcopyright, GG Giles, J GAtextsuperscriptmez-Aracena, AM Hodge, FB Hu, J Jansson, I Johansson, K Khaw, W Koh, RN Lemaitre, L Lind, RN Luben, EB Rimm, Ulf RisAcopyrightrus, C Samieri, PW Franks, DS Siscovick, M Stampfer, Lyn Steffen, BT Steffen, MY Tsai, Rob van Dam, S Voutilainen, WC Willett, M Woodward, D Mozaffarian, C Heart, Research Aging, Research Outcomes. (2016) {\"{I}}-3 Polyunsaturated Fatty Acid Biomarkers and Coronary Heart Disease: Pooling Project of 19~{C}ohort Studies. JAMA internal medicine 176 ():1155-1166.

L Chaker, C Baumgartner, WPJ den Elzen, T Collet, AM Ikram, MR Blum, A Dehghan, C Drechsler, RN Luben, MLP Portegies, G Iervasi, M Medici, DJ Stott, RP Dullaart, Ian Ford, A Bremner, AB Newman, C Wanner, JA Sgarbi, M DAPrr, WT Longstreth, BM Psaty, L Ferrucci, Rui Maciel, RG Westendorp, WJ Jukema, G Ceresini, M Imaizumi, A Hofman, SJL Bakker, JA Franklyn, K Khaw, DC Bauer, JP Walsh, S Razvi, J Gussekloo, H VAPlzke, OH Franco, AR Cappola, N Rodondi, RP Peeters, T Collaboration. (2016) Thyroid Function Within the Reference Range and the Risk of Stroke: An Individual Participant Data Analysis. The Journal of clinical endocrinology and metabolism 101 ():4270-4282.

P Chamnan, RK Simmons, SJ Sharp, K Khaw, NJ Wareham, SJ Griffin. (2016) Repeat Cardiovascular Risk Assessment after Four Years: Is There Improvement in Risk Prediction? PLoS One 11 (2):e0147417.

N Murphy, AJ Cross, M Abubakar, M Jenab, K Aleksandrova, M Boutron-Ruault, L Dossus, A Racine, T KAsfrac, VA Katzke, A TjAcnneland, KEN Petersen, Kim Overvad, RJ QuirAtextsuperscripts, P Jakszyn, E Molina-Montes, M Dorronsoro, J Huerta, A Barricarte, K Khaw, N Wareham, RC Travis, A Trichopoulou, P Lagiou, D Trichopoulos, G Masala, V Krogh, R Tumino, P Vineis, S Panico, B Bueno-de-Mesquita, PD Siersema, PH Peeters, B Ohlsson, U Ericson, R Palmqvist, H NystrAPm, E Weiderpass, G Skeie, H Freisling, Y Kong, K Tsilidis, DC Muller, E Riboli, MJ Gunter. (2016) A Nested Case-Control Study of Metabolically Defined Body Size Phenotypes and Risk of Colorectal Cancer in the {Europe}an Prospective Investigation into Cancer and Nutrition (EPIC). PLoS medicine 13 ():e1001988.

C Pinnock, JLY Yip, AP Khawaja, R Luben, S Hayat, DC Broadway, PJ Foster, K Khaw, N Wareham. (2016) Topical Beta-Blockers and Cardiovascular Mortality: Systematic Review and Meta-Analysis with Data from the EPIC-Norfolk Cohort Study. Ophthalmic epidemiology 23 ():277-284.

R Pfister, J Bragelmann, G Michels, NJ Wareham, R Luben, K Khaw. (2015) Performance of the CHARGE-AF risk model for incident atrial fibrillation in the EPIC Norfolk cohort. Eur J Prev Cardiol 22 (7):932-939.

R Scragg, D Waayer, AW Stewart, CMM Lawes, Les Toop, J Murphy, K Khaw, Jr Camargo. (2015) The Vitamin DAssessment (ViDA) Study: design of a randomized controlled trial of vitamin D supplementation for the prevention of cardiovascular disease, acute respiratory infection, falls and non-vertebral fractures. J Steroid Biochem Mol Biol ():.

D Saleheen, R Scott, S Javad, Wei Zhao, A Rodrigues, A Picataggi, D Lukmanova, ML Mucksavage, R Luben, J Billheimer, JJP Kastelein, MS Boekholdt, K Khaw, N Wareham, DJ Rader. (2015) Association of {HDL} cholesterol efflux capacity with incident coronary heart disease events: a prospective case-control study. Lancet Diabetes Endocrinol 3 (7):507-513.

A Vogiatzoglou, AA Mulligan, A Bhaniani, MAH Lentjes, A McTaggart, RN Luben, C Heiss, M Kelm, MW Merx, JPE Spencer, H Schroeter, K Khaw, GGC Kuhnle. (2015) Associations between flavan-3-ol intake and CVD risk in the Norfolk cohort of the {Europe}an Prospective Investigation into Cancer (EPIC-Norfolk). Free Radic Biol Med ():.

JLY Yip, AP Khawaja, MPY Chan, DC Broadway, T Peto, A Tufail, R Luben, S Hayat, A Bhaniani, NJ Wareham, K Khaw, PJ Foster. (2015) Cross Sectional and Longitudinal Associations between Cardiovascular Risk Factors and Age Related Macular Degeneration in the EPIC-Norfolk Eye Study. PLoS One 10 (7):e0132565.

BO AAsvold, LJ Vatten, T Bjoro, DC Bauer, A Bremner, AR Cappola, G Ceresini, WPJ den Elzen, L Ferrucci, OH Franco, JA Franklyn, J Gussekloo, G Iervasi, M Imaizumi, PM Kearney, K Khaw, Rui Maciel, AB Newman, RP Peeters, BM Psaty, S Razvi, JA Sgarbi, DJ Stott, S Trompet, MPJ Vanderpump, H Volzke, JP Walsh, RGJ Westendorp, N Rodondi, T, Collaboration. (2015) Thyroid function within the normal range and risk of coronary heart disease: an individual participant data analysis of 14 cohorts. JAMA Intern Med 175 (6):1037-1047.

ET Aasheim, SJ Sharp, PN Appleby, MJ Shipley, MAH Lentjes, K Khaw, E Brunner, Tim Key, NJ Wareham. (2015) Tinned fruit consumption and mortality in three prospective cohorts. PLoS One 10 (2):e0117796.

HT Jorstad, EB Colkesen, MS Boekholdt, Jan Tijssen, NJ Wareham, K Khaw, Ron Peters. (2015) Estimated 10-year cardiovascular mortality seriously underestimates overall cardiovascular risk. Heart ():.

HT Jorstad, EB Colkesen, M Minneboo, Ron Peters, MS Boekholdt, Jan Tijssen, NJ Wareham, K Khaw. (2015) The Systematic COronary Risk Evaluation ({SC}ORE) in a large UK population: 10-year follow-up in the EPIC-Norfolk prospective population study. Eur J Prev Cardiol 22 (1):119-126.

M Guardiola, HJ Exeter, C Perret, L Folkersen, F Hooft, Per Eriksson, A Franco-Cereceda, G Paulsson-Berne, J Palmen, K Li, JA Cooper, K Khaw, Z Mallat, Ewa Ninio, S Karabina, SE Humphries, MS Boekholdt, MV Holmes, PJ Talmud. (2015) PLA2G10 Gene Variants, sPLA2~{A}ctivity, and Coronary Heart Disease Risk. Circ Cardiovasc Genet 8 (2):356-362.

K Khaw, R Luben, N Wareham. (2015) Reply to WB Grant. Am J Clin Nutr 102 (1):230-231.

C Kwok, MS Boekholdt, MAH Lentjes, YK Loke, RN Luben, JK Yeong, NJ Wareham, PK Myint, K Khaw. (2015) Habitual chocolate consumption and risk of cardiovascular disease among healthy men and women. Heart 101 (16):1279-1287.

S Lachman, Ron Peters, M Lentjes, AA Mulligan, RN Luben, NJ Wareham, K Khaw, MS Boekholdt. (2015) Ideal cardiovascular health and risk of cardiovascular events in the EPIC-Norfolk prospective population study. Eur J Prev Cardiol ():.

PK Myint, KR Hawkins, AB Clark, RN Luben, NJ Wareham, KT Khaw, AM Wilson. (2015) Long-term mortality of hospitalized pneumonia in the EPIC-Norfolk cohort. Epidemiol Infect ():1-7.

Z Ye, PC Haycock, D Gurdasani, C Pomilla, MS Boekholdt, S Tsimikas, K Khaw, NJ Wareham, MS Sandhu, NG Forouhi. (2014) The Association Between Circulating Lipoprotein(a) and Type 2 Diabetes: Is It Causal? Diabetes 63 (1):332-342.

MAH Lentjes, AA Welch, AA Mulligan, RN Luben, NJ Wareham, K Khaw. (2014) Cod liver oil supplement consumption and health: cross-sectional results from the EPIC-Norfolk cohort study. Nutrients 6 (10):4320-4337.

Max Leenders, HC Boshuizen, P Ferrari, PD Siersema, Kim Overvad, A Tjonneland, A Olsen, M Boutron-Ruault, L Dossus, L Dartois, R Kaaks, K Li, H Boeing, MM Bergmann, A Trichopoulou, P Lagiou, D Trichopoulos, D Palli, V Krogh, S Panico, R Tumino, P Vineis, PHM Peeters, E Weiderpass, D Engeset, T Braaten, M Redondo, A Agudo, M Sanchez, P Amiano, J Huerta, Eva Ardanaz, I Drake, E Sonestedt, I Johansson, A Winkvist, K Khaw, NJ Wareham, TJ Key, KE Bradbury, M Johansson, I Licaj, MJ Gunter, N Murphy, E Riboli, B Bueno-de-Mesquita. (2014) Fruit and vegetable intake and cause-specific mortality in the EPIC study. Eur J Epidemiol 29 (9):639-652.

N Mavaddat, JM Valderas, R van der Linde, K Khaw, A Kinmonth. (2014) Association of self-rated health with multimorbidity, chronic disease and psychosocial factors in a large middle-aged and older cohort from general practice: a cross-sectional study. BMC Fam Pract 15 (1):185.

P Myint, C Fox, C Kwok, RN Luben, NJ Wareham, K Khaw. (2014) Total anticholinergic burden and risk of mortality and cardiovascular disease over 10 years in 21,636~{m}iddle-aged and older men and women of EPIC-Norfolk prospective population study. Age Ageing ():.

P Myint, C Kwok, RN Luben, NJ Wareham, K Khaw. (2014) Body fat percentage, body mass index and waist-to-hip ratio as predictors of mortality and cardiovascular disease. Heart ():.

C Rheaume, BJ Arsenault, J Despres, Faha, MS Boekholdt, NJ Wareham, K Khaw, Mbb Chir. (2014) Impact of abdominal obesity and systemic hypertension on risk of coronary heart disease in men and women: the EPIC-Norfolk Population Study. J Hypertens 32 (11):2224-30; discussion 2230.

JRB Perry, F Day, CE Elks, P Sulem, DJ Thompson, T Ferreira, C He, DI Chasman, T Esko, G Thorleifsson, Eva Albrecht, Wei Ang, T Corre, DL Cousminer, B Feenstra, N Franceschini, A Ganna, AD Johnson, S Kjellqvist, KL Lunetta, G McMahon, IM Nolte, L Paternoster, E Porcu, AV Smith, L Stolk, A Teumer, N Tvsernikova, E Tikkanen, S Ulivi, EK Wagner, N Amin, LJ Bierut, EM Byrne, J Hottenga, DL Koller, M Mangino, TH Pers, LM Yerges-Armstrong, J Zhao, IL Andrulis, H Anton-Culver, F Atsma, S Bandinelli, MW Beckmann, J Benitez, C Blomqvist, SE Bojesen, MK Bolla, B Bonanni, H Brauch, H Brenner, JE Buring, J Chang-Claude, S Chanock, J Chen, G Chenevix-Trench, MJ Collee, FJ Couch, D Couper, AD Coviello, A Cox, K Czene, A Dadamo, G Smith, I De Vivo, EW Demerath, Joe Dennis, P Devilee, AK Dieffenbach, AM Dunning, G Eiriksdottir, JG Eriksson, PA Fasching, L Ferrucci, D Flesch-Janys, H Flyger, T Foroud, L Franke, ME Garcia, M Garcia-Closas, F Geller, Eco de Geus, GG Giles, DF Gudbjartsson, V Gudnason, P Guenel, S Guo, Per Hall, Ute Hamann, R Haring, CA Hartman, AC Heath, A Hofman, MJ Hooning, JL Hopper, FB Hu, DJ Hunter, D Karasik, DP Kiel, JA Knight, V Kosma, Z Kutalik, S Lai, D Lambrechts, A Lindblom, R Magi, PK Magnusson, A Mannermaa, NG Martin, G Masson, PF McArdle, WL McArdle, M Melbye, K Michailidou, E Mihailov, L Milani, RL Milne, H Nevanlinna, P Neven, EA Nohr, AJ Oldehinkel, Ben Oostra, A Palotie, M Peacock, NL Pedersen, P Peterlongo, J Peto, PDP Pharoah, DS Postma, A Pouta, K Pylkas, P Radice, S Ring, F Rivadeneira, A Robino, LM Rose, A Rudolph, V Salomaa, S Sanna, D Schlessinger, MK Schmidt, MC Southey, U Sovio, MJ Stampfer, D Stockl, AM Storniolo, NJ Timpson, J Tyrer, JA Visser, P Vollenweider, H Volzke, G Waeber, M Waldenberger, H Wallaschofski, Qin Wang, G Willemsen, R Winqvist, BHR Wolffenbuttel, MJ Wright, Ovarian Australian, , Network, , kConFab, L, Study, I, Consortium, Growth Early, DI Boomsma, MJ Econs, K Khaw, RJF Loos, MI McCarthy, GW Montgomery, JP Rice, EA Streeten, U Thorsteinsdottir, CM van Duijn, BZ Alizadeh, S Bergmann, E Boerwinkle, HA Boyd, L Crisponi, P Gasparini, C Gieger, Harr. (2014) Parent-of-origin-specific allelic associations among 106 genomic loci for age at menarche. Nature 514 (7520):92-97.

R Pfister, G Michels, J Bragelmann, SJ Sharp, R Luben, NJ Wareham, K Khaw. (2014) Plasma vitamin C and risk of hospitalisation with diagnosis of atrial fibrillation in men and women in EPIC-Norfolk prospective study. Int J Cardiol 177 (3):830-835.

R Pfister, G Michels, SJ Sharp, R Luben, NJ Wareham, K Khaw. (2014) Estimated urinary sodium excretion and risk of heart failure in men and women in the EPIC-Norfolk study. Eur J Heart Fail ():.

R Pfister, G Michels, SJ Sharp, R Luben, NJ Wareham, K Khaw. (2014) Low bone mineral density predicts incident heart failure in men and women: the EPIC ({Europe}an Prospective Investigation into Cancer and Nutrition)-Norfolk prospective study. JACC Heart Fail 2 (4):380-389.

L Pennells, S Kaptoge, Ian White, SG Thompson, AM Wood, Risk Emerging. (2014) Assessing risk prediction models using individual participant data from multiple studies. Am J Epidemiol 179 (5):621-632.

R Chowdhury, S Warnakula, S Kunutsor, F Crowe, HA Ward, L Johnson, OH Franco, AS Butterworth, NG Forouhi, SG Thompson, K Khaw, D Mozaffarian, J Danesh, E Di Angelantonio. (2014) Association of dietary, circulating, and supplement fatty acids with coronary risk: a systematic review and meta-analysis. Ann Intern Med 160 (6):398-406.

P Ferrari, I Licaj, DC Muller, P Andersen, M Johansson, H Boeing, E Weiderpass, L Dossus, L Dartois, Guy Fagherazzi, KE Bradbury, K Khaw, N Wareham, EJ Duell, A Barricarte, E Molina-Montes, C Sanchez, L Arriola, P Wallstrom, A Tjonneland, A Olsen, A Trichopoulou, V Benetou, D Trichopoulos, R Tumino, C Agnoli, C Sacerdote, D Palli, K Li, R Kaaks, P Peeters, J Beulens, L Nunes, M Gunter, T Norat, Kim Overvad, P Brennan, E Riboli, I Romieu. (2014) Lifetime alcohol use and overall and cause-specific mortality in the {Europe}an Prospective Investigation into Cancer and nutrition (EPIC) study. BMJ Open 4 (7):e005245.

D Engeset, T Braaten, B Teucher, T Kuhn, H Bueno-de-Mesquita, Max Leenders, A Agudo, MM Bergmann, E Valanou, A Naska, A Trichopoulou, TJ Key, FL Crowe, Kim Overvad, E Sonestedt, A Mattiello, PH Peeters, M Wennberg, J Jansson, M Boutron-Ruault, L Dossus, L Dartois, K Li, A Barricarte, H Ward, E Riboli, C Agnoli, J Huerta, M Sanchez, R Tumino, JM Altzibar, P Vineis, G Masala, P Ferrari, DC Muller, M Johansson, LM Redondo, A Tjonneland, A Olsen, K Olsen, M Brustad, G Skeie, E Lund. (2014) Fish consumption and mortality in the {Europe}an Prospective Investigation into Cancer and Nutrition cohort. Eur J Epidemiol ():.

ERFC, E Di-Angelantonio, , Gao, , Khan, , Butterworth, , Wormser, , Kaptoge, S Kondapally-Seshasai, , Thompson, , Sarwar, , Willeit, , Ridker, , Barr, , Khaw, , Psaty, , Brenner, , Balkau, , Dekker, , Lawlor, , Daimon, , Willeit, , Nj\olstad, , Nissinen, , Brunner, , Kuller, , Price, , Sundstr"om, , Knuiman, , Feskens, , Verschuren, , Wald, , Bakker, , Whincup, , Ford, , Goldbourt, , G\omez-de-la-C\amara, , Gallacher, , Simons, , Rosengren, , Sutherland, , Bj"orkelund, , Blazer, , Wassertheil-Smoller, , Onat, A Marin-Ibanez, , Casiglia, , Jukema, , Simpson, , Giampaoli, , Nordestgaard, , Selmer, , Wennberg, , Kauhanen, , Salonen, , Dankner, , Barrett-Connor, , Kavousi, , Gudnason, , Evans, , Wallace, , Cushman, , DAgostino, , Umans, , Kiyohara, , Nakagawa, , Sato, , Gillum, , Folsom, YT Schouw, , Moons, , Griffin, , Sattar, , Wareham, , Selvin, , Thompson, , Danesh. (2014) Glycated hemoglobin measurement and prediction of cardiovascular disease. JAMA 311 (12):1225-1233.

MV Holmes, CE Dale, L Zuccolo, RJ Silverwood, Y Guo, Z Ye, D Prieto-Merino, A Dehghan, S Trompet, A Wong, A Cavadino, D Drogan, S Padmanabhan, S Li, A Yesupriya, M Leusink, J Sundstrom, JA Hubacek, H Pikhart, DI Swerdlow, AG Panayiotou, SA Borinskaya, C Finan, S Shah, KB Kuchenbaecker, T Shah, J Engmann, L Folkersen, Per Eriksson, F Ricceri, O Melander, C Sacerdote, DM Gamble, S Rayaprolu, OA Ross, S McLachlan, O Vikhireva, I Sluijs, RA Scott, V Adamkova, L Flicker, FM van Bockxmeer, C Power, P Marques-Vidal, Tom Meade, MG Marmot, JM Ferro, S Paulos-Pinheiro, SE Humphries, PJ Talmud, I Leach, N Verweij, A Linneberg, Tea Skaaby, PA Doevendans, MJ Cramer, Pim van der Harst, OH Klungel, NF Dowling, AF Dominiczak, M Kumari, AN Nicolaides, C Weikert, H Boeing, S Ebrahim, Tom Gaunt, JF Price, L Lannfelt, A Peasey, R Kubinova, A Pajak, S Malyutina, MI Voevoda, A Tamosiunas, A {Maitland-van der Zee}, PE Norman, GJ Hankey, MM Bergmann, A Hofman, OH Franco, J Cooper, J Palmen, W Spiering, Pim Jong, D Kuh, R Hardy, AG Uitterlinden, AM Ikram, Ian Ford, E Hypponen, OP Almeida, NJ Wareham, K Khaw, A Hamsten, LN Husemoen, A Tjonneland, JS Tolstrup, E Rimm, JWJ Beulens, MWM Verschuren, CN Onland-Moret, MH Hofker, GS Wannamethee, PH Whincup, R Morris, AM Vicente, H Watkins, M Farrall, WJ Jukema, J Meschia, AL Cupples, SJ Sharp, M Fornage, C Kooperberg, AZ LaCroix, JY Dai, MB Lanktree, DS Siscovick, E Jorgenson, B Spring, J Coresh, Yun Li, SG Buxbaum, PJ Schreiner, CR Ellison, MY Tsai, SR Patel, S Redline, AD Johnson, Ron Hoogeveen, H Hakonarson, JI Rotter, E Boerwinkle, PIW Bakker, M Kivimaki, FW Asselbergs, N Sattar, DA Lawlor, J Whittaker, G Smith, K Mukamal, BM Psaty, JG Wilson, LA Lange, A Hamidovic, AD Hingorani, BG Nordestgaard, M Bobak, DA Leon, C Langenberg, Tom Palmer, AP Reiner, BJ Keating, F Dudbridge, JP Casas, I, Consortium. (2014) Association between alcohol and cardiovascular disease: Mendelian randomisation analysis based on individual participant data. BMJ 349 ():g4164.

MV Holmes, HJ Exeter, L Folkersen, CP Nelson, M Guardiola, JA Cooper, R Sofat, MS Boekholdt, K Khaw, K Li, AJP Smith, F Hooft, Per Eriksson, A Franco-Cereceda, FW Asselbergs, JMA Boer, CN Onland-Moret, M Hofker, J Erdmann, M Kivimaki, M Kumari, AP Reiner, BJ Keating, SE Humphries, AD Hingorani, Z Mallat, NJ Samani, PJ Talmud, Consortium IoG.. (2014) Novel genetic approach to investigate the role of plasma secretory phospholipase A2 (sPLA2)-V isoenzyme in coronary heart disease: modified Mendelian randomization analysis using PLA2G5 expression levels. Circ Cardiovasc Genet 7 (2):144-150.

MV Holmes, R Frikke-Schmidt, D Melis, R Luben, FW Asselbergs, JMA Boer, J Cooper, J Palmen, Pia Horvat, J Engmann, K Li, CN Onland-Moret, MH Hofker, M Kumari, BJ Keating, JA Hubacek, V Adamkova, R Kubinova, M Bobak, K Khaw, BG Nordestgaard, N Wareham, SE Humphries, C Langenberg, A Tybjaerg-Hansen, PJ Talmud. (2014) A systematic review and meta-analysis of 130,000 individuals shows smoking does not modify the association of APOE genotype on risk of coronary heart disease. Atherosclerosis 237 (1):5-12.

K Khaw, R Luben, N Wareham. (2014) Serum 25-hydroxyvitamin D, mortality, and incident cardiovascular disease, respiratory disease, cancers, and fractures: a 13-y prospective population study. Am J Clin Nutr 100 (5):1361-1370.

Yue Leng, NWJ Wainwright, FP Cappuccio, PG Surtees, S Hayat, R Luben, C Brayne, K Khaw. (2014) Daytime napping and the risk of all-cause and cause-specific mortality: a 13-year follow-up of a British population. Am J Epidemiol 179 (9):1115-1124.

S Ahmadi-Abhari, RN Luben, NJ Wareham, K Khaw. (2013) Seventeen year risk of all-cause and cause-specific mortality associated with C-reactive protein, fibrinogen and leukocyte count in men and women: the EPIC-Norfolk study. Eur J Epidemiol 28 (7):541-550.

S Ahmadi-Abhari, RN Luben, NJ Wareham, K Khaw. (2013) Distribution and determinants of C-reactive protein in the older adult population: {Europe}an Prospective Investigation into Cancer-Norfolk study. Eur J Clin Invest 43 (9):899-911.

S Ahmadi-Abhari, RN Luben, NJ Wareham, K Khaw. (2013) C-reactive protein and fracture risk: {Europe}an prospective investigation into Cancer Norfolk Study. Bone 56 (1):67-72.

MM Bergmann, J Rehm, K Klipstein-Grobusch, H Boeing, M Schutze, D Drogan, Kim Overvad, A Tjonneland, J Halkjaer, Guy Fagherazzi, M Boutron-Ruault, F Clavel-Chapelon, B Teucher, R Kaaks, A Trichopoulou, V Benetou, D Trichopoulos, D Palli, V Pala, R Tumino, P Vineis, J Beulens, M Redondo, EJ Duell, E Molina-Montes, C Navarro, A Barricarte, L Arriola, NE Allen, FL Crowe, K Khaw, N Wareham, D Romaguera, PA Wark, I Romieu, L Nunes, E Riboli, P Ferrari. (2013) The association of pattern of lifetime alcohol use and cause of death in the {Europe}an Prospective Investigation into Cancer and Nutrition (EPIC) study. Int J Epidemiol 42 (6):1772-1790.

M den Hoed, M Eijgelsheim, T Esko, BJJM Brundel, DS Peal, DM Evans, IM Nolte, AV Segre, H Holm, RE Handsaker, H Westra, T Johnson, A Isaacs, J Yang, A Lundby, J Zhao, Y Kim, M Go, P Almgren, M Bochud, G Boucher, MC Cornelis, D Gudbjartsson, D Hadley, Pim van der Harst, C Hayward, M den Heijer, W Igl, AU Jackson, Z Kutalik, J Luan, JP Kemp, K Kristiansson, C Ladenvall, M Lorentzon, May Montasser, OT Njajou, PF OReilly, S Padmanabhan, B St Pourcain, T Rankinen, P Salo, T Tanaka, NJ Timpson, V Vitart, L Waite, W Wheeler, W Zhang, HHM Draisma, MF Feitosa, KF Kerr, PA Lind, E Mihailov, CN Onland-Moret, Ci Song, MN Weedon, W Xie, L Yengo, D Absher, CM Albert, A Alonso, Dan Arking, PIW de Bakker, B Balkau, C Barlassina, P Benaglio, JC Bis, N Bouatia-Naji, S Brage, SJ Chanock, PS Chines, M Chung, D Darbar, C Dina, M Dorr, P Elliott, SB Felix, K Fischer, C Fuchsberger, Eco de Geus, P Goyette, V Gudnason, TB Harris, A Hartikainen, Aki Havulinna, SR Heckbert, AA Hicks, A Hofman, S Holewijn, F Hoogstra-Berends, J Hottenga, MK Jensen, Asa Johansson, J Junttila, S Kaab, B Kanon, S Ketkar, K Khaw, JW Knowles, AS Kooner, Jan Kors, M Kumari, L Milani, P Laiho, EG Lakatta, C Langenberg, M Leusink, Y Liu, RN Luben, KL Lunetta, SN Lynch, MRP Markus, P Marques-Vidal, I Leach, WL McArdle, SA McCarroll, SE Medland, KA Miller, GW Montgomery, AC Morrison, M Muller-Nurasyid, Pau Navarro, M Nelis, JR OConnell, CJ ODonnell, Ken Ong, AB Newman, A Peters, O Polasek, A Pouta, PP Pramstaller, BM Psaty, DC Rao, SM Ring, EJ Rossin, D Rudan, S Sanna, RA Scott, JS Sehmi, S Sharp, JT Shin, AB Singleton, AV Smith, N Soranzo, Tim Spector, C Stewart, HM Stringham, KV Tarasov, AG Uitterlinden, L Vandenput, S Hwang, JB Whitfield, C Wijmenga, SH Wild, G Willemsen, JF Wilson, JCM Witteman, A Wong, Q Wong, Y Jamshidi, P Zitting, JMA Boer, DI Boomsma, IB Borecki, CM van Duijn, Ulf Ekelund, NG Forouhi, P Froguel, A Hingorani, E Ingelsson, M Kivimaki, RA Kronmal, D Kuh, L Lind, NG Martin, Ben Oostra, NL Pedersen, T Quertermous, JI Rotter, YT van der Schouw, MWM Verschuren, M Walker, D Albanes, DO Arnar, TL Assimes, Bandin. (2013) Identification of heart rate-associated loci and their effects on cardiac conduction and rhythm disorders. Nat Genet 45 (6):621-631.

Ron Do, CJ Willer, EM Schmidt, S Sengupta, Chi Gao, GM Peloso, S Gustafsson, S Kanoni, A Ganna, Jin Chen, ML Buchkovich, S Mora, JS Beckmann, JL Bragg-Gresham, H Chang, Aye Demirkan, HM Den Hertog, , Donnelly, , Ehret, , Esko, , Feitosa, , Ferreira, , Fischer, , Fontanillas, , Fraser, , Freitag, , Gurdasani, , Heikkil"a, , Hypp"onen, , Isaacs, , Jackson, , Johansson, , Johnson, , Kaakinen, , Kettunen, , Kleber, , Li, , Luan, , Lyytik"ainen, , Magnusson, , Mangino, , Mihailov, , Montasser, , M"uller-Nurasyid, , Nolte, , OConnell, , Palmer, , Perola, , Petersen, , Sanna, , Saxena, , Service, , Shah, , Shungin, , Sidore, , Song, , Strawbridge, , Surakka, , Tanaka, , Teslovich, , Thorleifsson, EG Herik, , Voight, , Volcik, , Waite, , Wong, , Wu, , Zhang, , Absher, , Asiki, , Barroso, , Been, , Bolton, , Bonnycastle, , Brambilla, , Burnett, , Cesana, , Dimitriou, , Doney, , D"oring, , Elliott, , Epstein, , Eyjolfsson, , Gigante, , Goodarzi, , Grallert, , Gravito, , Groves, , Hallmans, , Hartikainen, , Hayward, , Hernandez, , Hicks, , Holm, , Hung, , Illig, , Jones, , Kaleebu, , Kastelein, , Khaw, , Kim, , Klopp, , Komulainen, , Kumari, , Langenberg, , Lehtim"aki, , Lin, , Lindstr"om, , Loos, , Mach, , McArdle, , Meisinger, , Mitchell, , M"uller, , Nagaraja, , Narisu, , Nieminen, , Nsubuga, , Olafsson, , Ong, , Palotie, , Papamarkou, , Pomilla, , Pouta, , Rader, , Reilly, , Ridker, , Rivadeneira, , Rudan, , Ruokonen, , Samani, , Scharnagl, , Seeley, , Silander, , Stan\vc\akov\a, , Stirrups, , Swift, , Tiret, , Uitterlinden, JL van-Pelt, , Vedantam, , Wainwright, , Wijmenga, , Wild, , Willemsen, , Wilsgaard, , Wilson, , Young, , Zhao, , Adair, , Arveiler, , Assimes, , Bandinelli, , Bennett, , Bochud, , Boehm, , Boomsma, , Borecki, , Bornstein, , Bovet, , Burnier, , Campbell, , Chakravarti, , Chambers, , Chen, , Collins, , Cooper, , Danesh, , Dedoussis, Ulf de-Faire, , Feranil, , Ferri`eres, , Ferrucci, , Freimer, , Gieger, , Groop, , Gudnason, , Gyllensten, , Hamsten, , Harris, , Hingorani, , Hirschhorn, , Hofman, , Hovingh, H . (2013) Common variants associated with plasma triglycerides and risk for coronary artery disease. Nat Genet 45 (11):1345-1352.

P Chamnan, RK Simmons, KT Khaw, NJ Wareham, SJ Griffin. (2013) Change in HbA1c over 3 years does not improve the prediction of cardiovascular disease over and above HbA1c measured at a single time point. Diabetologia 56 (5):1004-1011.

JM Chapman, P Giral, PJ Barter. (2013) The conundrum of C-reactive protein as a risk marker for cardiovascular risk assessment: insight from EPIC-Norfolk and JUPITER. Eur Heart J 34 (18):1318-1320.

ME Emans, CAJM Gaillard, R Pfister, MW Tanck, MS Boekholdt, NJ Wareham, K Khaw. (2013) Red cell distribution width is associated with physical inactivity and heart failure, independent of established risk factors, inflammation or iron metabolism; the EPIC-Norfolk study. Int J Cardiol ():.

MV Holmes, T Simon, HJ Exeter, L Folkersen, FW Asselbergs, M Guardiola, JA Cooper, J Palmen, JA Hubacek, KF Carruthers, BD Horne, KD Brunisholz, JL Mega, EPA van Iperen, M Li, M Leusink, S Trompet, JJW Verschuren, KG Hovingh, A Dehghan, CP Nelson, S Kotti, N Danchin, M Scholz, CL Haase, D Rothenbacher, DI Swerdlow, KB Kuchenbaecker, E Staines-Urias, A Goel, Ft van Hooft, K Gertow, Ulf de Faire, AG Panayiotou, E Tremoli, D Baldassarre, F Veglia, LM Holdt, F Beutner, Ron Gansevoort, GJ Navis, I Leach, LP Breitling, H Brenner, J Thiery, D Dallmeier, A Franco-Cereceda, JMA Boer, JW Stephens, MH Hofker, A Tedgui, A Hofman, AG Uitterlinden, V Adamkova, Jan Pitha, CN Onland-Moret, MJ Cramer, HM Nathoe, W Spiering, OH Klungel, M Kumari, PH Whincup, DA Morrow, PS Braund, AS Hall, AG Olsson, PA Doevendans, MD Trip, MD Tobin, A Hamsten, H Watkins, W Koenig, AN Nicolaides, D Teupser, Ian Day, JF Carlquist, Tom Gaunt, Ian Ford, N Sattar, S Tsimikas, GG Schwartz, DA Lawlor, RW Morris, MS Sandhu, R Poledne, A {Maitland-van der Zee}, K Khaw, BJ Keating, Pim van der Harst, JF Price, SR Mehta, S Yusuf, JCM Witteman, OH Franco, WJ Jukema, P de Knijff, A Tybjaerg-Hansen, DJ Rader, M Farrall, NJ Samani, M Kivimaki, KAA Fox, SE Humphries, JL Anderson, MS Boekholdt, Tom Palmer, Per Eriksson, G Pare, AD Hingorani, MS Sabatine, Z Mallat, JP Casas, PJ Talmud. (2013) Secretory phospholipase A(2)-IIA and cardiovascular disease: a mendelian randomization study. J Am Coll Cardiol 62 (21):1966-1976.

E Gkrania-Klotsas, C Langenberg, SJ Sharp, R Luben, K Khaw, NJ Wareham. (2013) Seropositivity and higher immunoglobulin g antibody levels against cytomegalovirus are associated with mortality in the population-based {Europe}an prospective investigation of cancer-norfolk cohort. Clin Infect Dis 56 (10):1421-1427.

D GLGC, U Bioinformatics, CJ Willer, EM Schmidt, S Sengupta, GM Peloso, S Gustafsson, S Kanoni, A Ganna, Jin Chen, ML Buchkovich, S Mora, JS Beckmann, JL Bragg-Gresham, H Chang, Aye Demirkan, HM Den Hertog, Ron Do, LA Donnelly, GB Ehret, T Esko, MF Feitosa, T Ferreira, K Fischer, P Fontanillas, RM Fraser, DF Freitag, D Gurdasani, K Heikkila, E Hypponen, A Isaacs, AU Jackson, Asa Johansson, T Johnson, M Kaakinen, J Kettunen, ME Kleber, X Li, J Luan, L Lyytikainen, PKE Magnusson, M Mangino, E Mihailov, May Montasser, M Muller-Nurasyid, IM Nolte, JR OConnell, CD Palmer, M Perola, A Petersen, S Sanna, R Saxena, SK Service, S Shah, D Shungin, C Sidore, Ci Song, RJ Strawbridge, Ida Surakka, T Tanaka, TM Teslovich, G Thorleifsson, EG Van den Herik, BF Voight, KA Volcik, LL Waite, A Wong, Y Wu, W Zhang, D Absher, G Asiki, I Barroso, LF Been, JL Bolton, LL Bonnycastle, P Brambilla, MS Burnett, G Cesana, M Dimitriou, ASF Doney, A Doring, P Elliott, SE Epstein, G Eyjolfsson, B Gigante, MO Goodarzi, H Grallert, ML Gravito, CJ Groves, G Hallmans, A Hartikainen, C Hayward, D Hernandez, AA Hicks, H Holm, Y Hung, T Illig, MR Jones, P Kaleebu, JJP Kastelein, K Khaw, E Kim, N Klopp, P Komulainen, M Kumari, C Langenberg, T Lehtimaki, S Lin, J Lindstrom, RJF Loos, F Mach, WL McArdle, C Meisinger, BD Mitchell, G Muller, R Nagaraja, N Narisu, TVM Nieminen, RN Nsubuga, I Olafsson, Ken Ong, A Palotie, T Papamarkou, C Pomilla, A Pouta, DJ Rader, MP Reilly, PM Ridker, F Rivadeneira, I Rudan, A Ruokonen, N Samani, H Scharnagl, J Seeley, K Silander, A Stancakova, K Stirrups, Amy Swift, L Tiret, AG Uitterlinden, JL van Pelt, S Vedantam, N Wainwright, C Wijmenga, SH Wild, G Willemsen, Tom Wilsgaard, JF Wilson, EH Young, J Zhao, LS Adair, D Arveiler, TL Assimes, S Bandinelli, F Bennett, M Bochud, BO Boehm, DI Boomsma, IB Borecki, SR Bornstein, P Bovet, M Burnier, H Campbell, A Chakravarti, JC Chambers, Y Chen, Fr Collins. (2013) Discovery and refinement of loci associated with lipid levels. Nat Genet 45 (11):1274-1283.

TA Khan, T Shah, D Prieto, W Zhang, J Price, GR Fowkes, J Cooper, PJ Talmud, SE Humphries, J Sundstrom, JA Hubacek, S Ebrahim, DA Lawlor, Y Ben-Shlomo, MR Abdollahi, AJC Slooter, Z Szolnoki, M Sandhu, N Wareham, R Frikke-Schmidt, A Tybjaerg-Hansen, G Fillenbaum, BT Heijmans, T Katsuya, G Gromadzka, A Singleton, L Ferrucci, J Hardy, B Worrall, SS Rich, Mar Matarin, J Whittaker, Tom Gaunt, P Whincup, R Morris, J Deanfield, Ann Donald, G Smith, M Kivimaki, M Kumari, L Smeeth, K Khaw, M Nalls, J Meschia, Kai Sun, R Hui, Ian Day, AD Hingorani, JP Casas. (2013) Apolipoprotein E genotype, cardiovascular biomarkers and risk of stroke: systematic review and meta-analysis of 14,015~{s}troke cases and pooled analysis of primary biomarker data from up to 60,883 individuals. Int J Epidemiol 42 (2):475-492.

Max Leenders, I Sluijs, MM Ros, HC Boshuizen, PD Siersema, P Ferrari, C Weikert, A Tjonneland, A Olsen, M Boutron-Ruault, F Clavel-Chapelon, L Nailler, B Teucher, K Li, H Boeing, MM Bergmann, A Trichopoulou, P Lagiou, D Trichopoulos, D Palli, V Pala, S Panico, R Tumino, C Sacerdote, PHM Peeters, CH van Gils, E Lund, D Engeset, M Redondo, A Agudo, M Sanchez, C Navarro, Eva Ardanaz, E Sonestedt, U Ericson, L Nilsson, K Khaw, NJ Wareham, TJ Key, FL Crowe, I Romieu, MJ Gunter, V Gallo, Kim Overvad, E Riboli, B Bueno-de-Mesquita. (2013) Fruit and Vegetable Consumption and Mortality: {Europe}an Prospective Investigation Into Cancer and Nutrition. Am J Epidemiol ():.

R Pfister, RN Luben, K Khaw, NJ Wareham. (2013) Common genetic variants of the natriuretic peptide gene locus are not associated with heart failure risk in participants in the EPIC-Norfolk study. Eur J Heart Fail 15 (6):624-627.

S Sahlqvist, A Goodman, RK Simmons, K Khaw, N Cavill, C Foster, R Luben, NJ Wareham, D Ogilvie. (2013) The association of cycling with all-cause, cardiovascular and cancer mortality: findings from the population-based EPIC-Norfolk cohort. BMJ Open 3 (11):e003797.

S Rohrmann, Kim Overvad, B Bueno-de-Mesquita, MU Jakobsen, R Egeberg, A Tjonneland, L Nailler, M Boutron-Ruault, F Clavel-Chapelon, V Krogh, D Palli, S Panico, R Tumino, F Ricceri, MM Bergmann, H Boeing, K Li, R Kaaks, K Khaw, NJ Wareham, FL Crowe, TJ Key, A Naska, A Trichopoulou, D Trichopoulos, Max Leenders, PHM Peeters, D Engeset, CL Parr, G Skeie, P Jakszyn, M Sanchez, JM Huerta, LM Redondo, A Barricarte, P Amiano, I Drake, E Sonestedt, G Hallmans, I Johansson, V Fedirko, I Romieux, P Ferrari, T Norat, AC Vergnaud, E Riboli, J Linseisen. (2013) Meat consumption and mortality--results from the {Europe}an Prospective Investigation into Cancer and Nutrition. BMC Med 11 ():63.

T Tanaka, JS Ngwa, FJA van Rooij, CM Zillikens, MK Wojczynski, AC Frazier-Wood, DK Houston, S Kanoni, RN Lemaitre, J Luan, V Mikkila, F Renstrom, E Sonestedt, J Zhao, AY Chu, Lu Qi, DI Chasman, M {de Oliveira Otto}, EJ Dhurandhar, MF Feitosa, I Johansson, K Khaw, KK Lohman, Ani Manichaikul, NM McKeown, D Mozaffarian, A Singleton, K Stirrups, J Viikari, Z Ye, S Bandinelli, I Barroso, P Deloukas, NG Forouhi, A Hofman, Y Liu, L Lyytikainen, KE North, M Dimitriou, G Hallmans, M Kahonen, C Langenberg, JM Ordovas, AG Uitterlinden, FB Hu, I Kalafati, O Raitakari, OH Franco, A Johnson, V Emilsson, JA Schrack, RD Semba, DS Siscovick, DK Arnett, IB Borecki, PW Franks, SB Kritchevsky, T Lehtimaki, RJF Loos, M Orho-Melander, JI Rotter, NJ Wareham, JCM Witteman, L Ferrucci, G Dedoussis, AL Cupples, JA Nettleton. (2013) Genome-wide meta-analysis of observational studies shows common genetic variants associated with macronutrient intake. Am J Clin Nutr 97 (6):1395-1402.

X Sim, RA Jensen, KM Ikram, M Cotch, X Li, S MacGregor, J Xie, A Smith, E Boerwinkle, P Mitchell, R Klein, BEK Klein, NL Glazer, T Lumley, B McKnight, BM Psaty, PTVM de Jong, A Hofman, F Rivadeneira, AG Uitterlinden, CM van Duijn, T Aspelund, G Eiriksdottir, TB Harris, F Jonasson, LJ Launer, Trust Wellcome, J Attia, PN Baird, S Harrap, EG Holliday, M Inouye, E Rochtchina, RJ Scott, A Viswanathan, G,BP Consortium, Guo Li, NL Smith, KL Wiggins, JZ Kuo, KD Taylor, AW Hewitt, NG Martin, GW Montgomery, C Sun, TL Young, DA Mackey, NR van Zuydam, ASF Doney, CNA Palmer, AD Morris, JI Rotter, SE Tai, V Gudnason, JR Vingerling, DS Siscovick, J Wang, TY Wong. (2013) Genetic loci for retinal arteriolar microcirculation. PLoS One 8 (6):e65804.

BM Sondermeijer, MS Boekholdt, JS Rana, JJP Kastelein, NJ Wareham, K Khaw. (2013) Clinical implications of JUPITER in a contemporary {Europe}an population: the EPIC-Norfolk prospective population study. Eur Heart J 34 (18):1350-1357.

BM Sondermeijer, JS Rana, BJ Arsenault, PK Shah, JJP Kastelein, NJ Wareham, MS Boekholdt, K Khaw. (2013) Non-{HDL} cholesterol vs. apo B for risk of coronary heart disease in healthy individuals: the EPIC-Norfolk prospective population study. Eur J Clin Invest 43 (10):1009-1015.

GM Singh, G Danaei, F Farzadfar, GA Stevens, M Woodward, D Wormser, S Kaptoge, G Whitlock, Q Qiao, S Lewington, E Di Angelantonio, S Hoorn, CMM Lawes, MK Ali, D Mozaffarian, M Ezzati, Burden Global, Epidemiology: Diabetes, Risk Emerging, Studies Prospective. (2013) The age-specific quantitative effects of metabolic risk factors on cardiovascular diseases and diabetes: a pooled analysis. PLoS One 8 (7):e65174.

RM van der Linde, N Mavaddat, R Luben, C Brayne, RK Simmons, K Khaw, A Kinmonth. (2013) Self-rated health and cardiovascular disease incidence: results from a longitudinal population-based cohort in Norfolk, UK. PLoS One 8 (6):e65290.

van Vliet-Ostaptchouk, den Hoed, J Luan, JH Zhao, KK Ong, vPJ Most, A Wong, R Hardy, D Kuh, vMM Klauw, M Bruinenberg, KT Khaw, BHR Wolffenbuttel, NJ Wareham, H Snieder, RJF Loos. (2013) Pleiotropic effects of obesity-susceptibility loci on metabolic traits: a meta-analysis of up to 37,874 individuals. Diabetologia 56 (10):2134-2146.

DF van Wijk, MS Boekholdt, NJ Wareham, S Ahmadi-Abhari, JJP Kastelein, ESG Stroes, K Khaw. (2013) C-reactive protein, fatal and nonfatal coronary artery disease, stroke, and peripheral artery disease in the prospective EPIC-Norfolk cohort study. Arterioscler Thromb Vasc Biol 33 (12):2888-2894.

D Gurdasani, B Sjouke, S Tsimikas, KG Hovingh, RN Luben, NWJ Wainwright, C Pomilla, NJ Wareham, K Khaw, MS Boekholdt, MS Sandhu. (2012) Lipoprotein(a) and risk of coronary, cerebrovascular, and peripheral artery disease: the EPIC-Norfolk prospective population study. Arterioscler Thromb Vasc Biol 32 (12):3058-3065.

E Gkrania-Klotsas, C Langenberg, SJ Sharp, R Luben, K Khaw, NJ Wareham. (2012) Higher immunoglobulin G antibody levels against cytomegalovirus are associated with incident ischemic heart disease in the population-based EPIC-Norfolk cohort. J Infect Dis 206 (12):1897-1903.

P Chamnan, RK Simmons, KT Khaw, NJ Wareham, SJ Griffin. (2012) Estimating the potential population impact of stepwise screening strategies for identifying and treating individuals at high risk of Type 2 diabetes: a modelling study. Diabet Med 29 (7):893-904.

T Collet, J Gussekloo, DC Bauer, WPJ den Elzen, AR Cappola, P Balmer, G Iervasi, BO AAsvold, JA Sgarbi, H Volzke, B Gencer, Rui Maciel, S Molinaro, A Bremner, RN Luben, P Maisonneuve, J Cornuz, AB Newman, K Khaw, RGJ Westendorp, JA Franklyn, E Vittinghoff, JP Walsh, N Rodondi, T, Collaboration. (2012) Subclinical hyperthyroidism and the risk of coronary heart disease and mortality. Arch Intern Med 172 (10):799-809.

B Gencer, T Collet, V Virgini, DC Bauer, J Gussekloo, AR Cappola, D Nanchen, WPJ den Elzen, P Balmer, RN Luben, M Iacoviello, V Triggiani, J Cornuz, AB Newman, K Khaw, WJ Jukema, RGJ Westendorp, E Vittinghoff, D Aujesky, N Rodondi, T, Collaboration. (2012) Subclinical thyroid dysfunction and the risk of heart failure events: an individual participant data analysis from 6 prospective cohorts. Circulation 126 (9):1040-1049.

FL Crowe, TJ Key, PN Appleby, K Overvad, EB Schmidt, R Egeberg, A Tjonneland, R Kaaks, B Teucher, H Boeing, C Weikert, A Trichopoulou, V Ouranos, E Valanou, G Masala, S Sieri, S Panico, R Tumino, G Matullo, H Bueno-de-Mesquita, JMA Boer, JWJ Beulens, vYT Schouw, JR Quiros, G Buckland, MJ Sanchez, M Dorronsoro, JM Huerta, C Moreno-Iribas, B Hedblad, JH Jansson, P Wennberg, KT Khaw, N Wareham, P Ferrari, AK Illner, SC Chuang, T Norat, J Danesh, E Riboli. (2012) Dietary fibre intake and ischaemic heart disease mortality: the {Europe}an Prospective Investigation into Cancer and Nutrition-Heart study. Eur J Clin Nutr 66 (8):950-956.

S Chuang, T Norat, N Murphy, A Olsen, A Tjonneland, Kim Overvad, M Boutron-Ruault, F Perquier, L Dartois, R Kaaks, B Teucher, MM Bergmann, H Boeing, A Trichopoulou, P Lagiou, D Trichopoulos, S Grioni, C Sacerdote, S Panico, D Palli, R Tumino, PHM Peeters, B Bueno-de-Mesquita, MM Ros, M Brustad, L AAsli, G Skeie, RJ Quiros, CA Gonzalez, M Sanchez, C Navarro, E Aicua, M Dorronsoro, I Drake, E Sonestedt, I Johansson, G Hallmans, T Key, F Crowe, K Khaw, N Wareham, P Ferrari, N Slimani, I Romieu, V Gallo, E Riboli, P Vineis. (2012) Fiber intake and total and cause-specific mortality in the {Europe}an Prospective Investigation into Cancer and Nutrition cohort. Am J Clin Nutr 96 (1):164-174.

JS Brand, YT van der Schouw, M Dowsett, E Folkerd, RN Luben, NJ Wareham, K Khaw. (2012) Testosterone, SHBG and differential white blood cell count in middle-aged and older men. Maturitas 71 (3):274-278.

R Zamora-Ros, V Knaze, L Lujan-Barroso, GGC Kuhnle, AA Mulligan, M Touillaud, N Slimani, I Romieu, N Powell, R Tumino, PHM Peeters, de Magistris, F Ricceri, E Sonestedt, I Drake, A Hjartaaker, G Skie, T Mouw, PA Wark, D Romaguera, H Bueno-de-Mesquita, M Ros, E Molina, S Sieri, JR Quiros, JM Huerta, A Tjonneland, J Halkjaer, G Masala, B Teucher, R Kaas, RC Travis, V Dilis, V Benetou, A Trichopoulou, P Amiano, E Ardanaz, H Boeing, J Forster, F Clavel-Chapelon, G Fagherazzi, F Perquier, G Johansson, I Johansson, A Cassidy, K Overvad, CA Gonzalez. (2012) Dietary intakes and food sources of phytoestrogens in the {Europe}an Prospective Investigation into Cancer and Nutrition (EPIC) 24-hour dietary recall cohort. Eur J Clin Nutr ():.

HA Ward, R Keogh, M Lentjes, RN Luben, NJ Wareham, KT Khaw. (2012) Fibre intake in relation to serum total cholesterol levels and CHD risk: a comparison of dietary assessment methods. Eur J Clin Nutr 66 (3):296-304.

R Pfister, G Michels, SJ Sharp, R Luben, NJ Wareham, K Khaw. (2012) Resting heart rate and incident heart failure in apparently healthy men and women in the EPIC-Norfolk study. Eur J Heart Fail 14 (10):1163-1170.

R Pfister, SJ Sharp, R Luben, NJ Wareham, K Khaw. (2012) Differential white blood cell count and incident heart failure in men and women in the EPIC-Norfolk study. Eur Heart J 33 (4):523-530.

D Melzer, NJ Osborne, WE Henley, R Cipelli, A Young, C Money, P McCormack, R Luben, K Khaw, NJ Wareham, TS Galloway. (2012) Urinary bisphenol A concentration and risk of future coronary artery disease in apparently healthy men and women. Circulation 125 (12):1482-1490.

K Ray, NWJ Wainwright, L Visser, J Witteman, M Breteler, B Ambegaonkar, A Hofman, B Stricker, N Wareham, K Khaw, M Sandhu. (2012) Changes in {HDL} cholesterol and cardiovascular outcomes after lipid modification therapy. Heart 98 (10):780-785.

K Khaw, MD Friesen, E Riboli, R Luben, N Wareham. (2012) Plasma phospholipid fatty acid concentration and incident coronary heart disease in men and women: the EPIC-Norfolk prospective study. PLoS Med 9 (7):e1001255.

TO Kilpelainen, CM Zillikens, A Stanvcakova, FM Finucane, JS Ried, C Langenberg, W Zhang, JS Beckmann, J Luan, L Vandenput, U Styrkarsdottir, Y Zhou, A Smith, J Zhao, N Amin, S Vedantam, S Shin, T Haritunians, Mao Fu, MF Feitosa, M Kumari, BV Halldorsson, E Tikkanen, M Mangino, C Hayward, Ci Song, AM Arnold, YS Aulchenko, Ben Oostra, H Campbell, AL Cupples, KE Davis, A Doring, G Eiriksdottir, K Estrada, J Fernandez-Real, M Garcia, C Gieger, NL Glazer, C Guiducci, A Hofman, SE Humphries, Bo Isomaa, LC Jacobs, A Jula, D Karasik, MK Karlsson, K Khaw, LJ Kim, M Kivimaki, N Klopp, B Kuhnel, J Kuusisto, Y Liu, O Ljunggren, M Lorentzon, RN Luben, B McKnight, Dan Mellstrom, BD Mitchell, V Mooser, J Moreno, S Mannisto, JR OConnell, L Pascoe, L Peltonen, B Peral, M Perola, BM Psaty, V Salomaa, DB Savage, RK Semple, T Skaric-Juric, G Sigurdsson, KS Song, TD Spector, A Syvanen, PJ Talmud, G Thorleifsson, U Thorsteinsdottir, AG Uitterlinden, CM van Duijn, A Vidal-Puig, SH Wild, AF Wright, DJ Clegg, E Schadt, JF Wilson, I Rudan, S Ripatti, IB Borecki, AR Shuldiner, E Ingelsson, J Jansson, RC Kaplan, V Gudnason, TB Harris, L Groop, DP Kiel, F Rivadeneira, M Walker, I Barroso, P Vollenweider, G Waeber, JC Chambers, JS Kooner, N Soranzo, JN Hirschhorn, K Stefansson, H Wichmann, C Ohlsson, S ORahilly, NJ Wareham, EK Speliotes, CS Fox, M Laakso, RJF Loos. (2011) Genetic variation near {IR}S1~{as}sociates with reduced adiposity and an impaired metabolic profile. Nat Genet 43 (8):753-760.

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P Chamnan, RK Simmons, R Jackson, KT Khaw, NJ Wareham, SJ Griffin. (2011) Non-diabetic hyperglycaemia and cardiovascular risk: moving beyond categorisation to individual interpretation of absolute risk. Diabetologia 54 (2):291-299.

Risk Emerging, D Wormser, S Kaptoge, E Angelantonio, AM Wood, L Pennells, A Thompson, N Sarwar, JR Kizer, DA Lawlor, BG Nordestgaard, P Ridker, V Salomaa, J Stevens, M Woodward, N Sattar, R Collins, SG Thompson, G Whitlock, J Danesh. (2011) Separate and combined associations of body-mass index and abdominal adiposity with cardiovascular disease: collaborative analysis of 58 prospective studies. Lancet 377 (9771):1085-1095.

M Cote, A Cartier, AQ Reuwer, BJ Arsenault, I Lemieux, J Despres, NJ Wareham, JJP Kastelein, MS Boekholdt, K Khaw. (2011) Adiponectin and Risk of Coronary Heart Disease in Apparently Healthy Men and Women (from the EPIC-Norfolk Prospective Population Study). Am J Cardiol ():.

CCGC, W Frances, Gao Pei, B Stephen, K Stephen, A Emanuele, S Tina, EC James, C Robert, D George, NG Borge, S Danish, SJ Nilesh, S Manjinder, A Sonia, PB Mark, S Liam, W John, P Juan, TG Simon, HD Aroon, D John. (2011) Association between C reactive protein and coronary heart disease: mendelian randomisation analysis based on individual participant data. BMJ 342 ():d548.

FL Crowe, AW Roddam, TJ Key, PN Appleby, Kim Overvad, MU Jakobsen, A Tjonneland, L Hansen, H Boeing, C Weikert, J Linseisen, R Kaaks, A Trichopoulou, G Misirli, P Lagiou, C Sacerdote, V Pala, D Palli, R Tumino, S Panico, B Bueno-de-Mesquita, J Boer, CH van Gils, JWJ Beulens, A Barricarte, L Rodriguez, N Larranaga, M Sanchez, M Tormo, G Buckland, E Lund, Bo Hedblad, O Melander, J Jansson, P Wennberg, NJ Wareham, N Slimani, I Romieu, M Jenab, J Danesh, V Gallo, T Norat, E Riboli, Prospective European, (EPIC)-Heart Nutrition. (2011) Fruit and vegetable intake and mortality from ischaemic heart disease: results from the {Europe}an Prospective Investigation into Cancer and Nutrition (EPIC)-Heart study. Eur Heart J 32 (10):1235-1243.

LN Broekhuizen, MS Boekholdt, BJ Arsenault, J Despres, ESG Stroes, JJP Kastelein, K Khaw, NJ Wareham. (2011) Physical activity, metabolic syndrome, and coronary risk: the EPIC-Norfolk prospective population study. Eur J Cardiovasc Prev Rehabil 18 (2):209-217.

JS Brand, NJ Wareham, M Dowsett, E Folkerd, YT van der Schouw, RN Luben, K Khaw. (2011) Associations of endogenous testosterone and SHBG with glycated haemoglobin in middle-aged and older men. Clin Endocrinol (Oxf) 74 (5):572-578.

K Wijndaele, S Brage, H Besson, K Khaw, SJ Sharp, R Luben, A Bhaniani, NJ Wareham, Ulf Ekelund. (2011) Television Viewing and Incident Cardiovascular Disease: Prospective Associations and Mediation Analysis in the EPIC Norfolk Study. PLoS One 6 (5):e20058.

K Wijndaele, S Brage, H Besson, K Khaw, SJ Sharp, R Luben, NJ Wareham, Ulf Ekelund. (2011) Television viewing time independently predicts all-cause and cardiovascular mortality: the EPIC Norfolk Study. Int J Epidemiol 40 (1):150-159.

H Schunkert, IR Konig, S Kathiresan, MP Reilly, TL Assimes, H Holm, M Preuss, AFR Stewart, M Barbalic, C Gieger, D Absher, Z Aherrahrou, H Allayee, D Altshuler, SS Anand, K Andersen, JL Anderson, D Ardissino, SG Ball, AJ Balmforth, TA Barnes, DM Becker, LC Becker, K Berger, JC Bis, MS Boekholdt, E Boerwinkle, PS Braund, MJ Brown, M Burnett, Ian Buysschaert, Cardiogenics, JF Carlquist, Li Chen, S Cichon, V Codd, RW Davies, G Dedoussis, A Dehghan, S Demissie, JM Devaney, P Diemert, Do Ron, A Doering, S Eifert, N Mokhtari, SG Ellis, R Elosua, JC Engert, SE Epstein, Ulf Faire, M Fischer, AR Folsom, J Freyer, B Gigante, D Girelli, S Gretarsdottir, V Gudnason, JR Gulcher, E Halperin, N Hammond, SL Hazen, A Hofman, BD Horne, T Illig, C Iribarren, GT Jones, WJ Jukema, MA Kaiser, Lee Kaplan, JJP Kastelein, K Khaw, JW Knowles, G Kolovou, A Kong, R Laaksonen, D Lambrechts, K Leander, G Lettre, Li Mingyao, W Lieb, C Loley, AJ Lotery, PM Mannucci, S Maouche, N Martinelli, PP McKeown, C Meisinger, T Meitinger, O Melander, P Merlini, V Mooser, T Morgan, TW Muhleisen, JB Muhlestein, T Munzel, K Musunuru, J Nahrstaedt, CP Nelson, MM Nothen, O Olivieri, RS Patel, CC Patterson, A Peters, F Peyvandi, Qu Liming, AA Quyyumi, DJ Rader, LS Rallidis, C Rice, FR Rosendaal, D Rubin, V Salomaa, LM Sampietro, MS Sandhu, E Schadt, A Schafer, A Schillert, S Schreiber, J Schrezenmeir, SM Schwartz, DS Siscovick, M Sivananthan, S Sivapalaratnam, A Smith, TB Smith, JD Snoep, N Soranzo, JA Spertus, K Stark, K Stirrups, M Stoll, WWH Tang, S Tennstedt, G Thorgeirsson, G Thorleifsson, M Tomaszewski, AG Uitterlinden, AM van Rij, BF Voight, NJ Wareham, GA Wells, Wichmann H-Erich, PS Wild, C Willenborg, JCM Witteman, BJ Wright, Ye Shu, T Zeller, A Ziegler, F Cambien, AH Goodall, AL Cupples, T Quertermous, W Marz, C Hengstenberg, S Blankenberg, WH Ouwehand, AS Hall, P Deloukas, JR Thompson, K Stefansson, R Roberts, U Thorsteinsdottir, CJ ODonnell, R McPherson, J Erdmann, t Consortium, NJ Samani. (2011) Large-scale association analysis identifies 13 new susceptibility loci for coronary artery disease. Nat Genet 43 (4):333-338.

SL Ricketts, KL Rensing, JM Holly, Li Chen, EH Young, R Luben, S Ashford, K Song, Xin Yuan, A Dehghan, BJ Wright, DM Waterworth, V Mooser, , Investigators, G Waeber, P Vollenweider, SE Epstein, MS Burnett, JM Devaney, HH Hakonarson, DJ Rader, MP Reilly, J Danesh, SG Thompson, AM Dunning, CM van Duijn, NJ Samani, R McPherson, NJ Wareham, K Khaw, MS Boekholdt, MS Sandhu. (2011) Prospective study of insulin-like growth factor-I, insulin-like growth factor-binding protein 3, genetic variants in the IGF1 and IGFBP3 genes and risk of coronary artery disease. Int J Mol Epidemiol Genet 2 (3):261-285.

R Pfister, D Barnes, RN Luben, KT Khaw, NJ Wareham, C Langenberg. (2011) Individual and cumulative effect of type 2 diabetes genetic susceptibility variants on risk of coronary heart disease. Diabetologia ():.

R Pfister, S Sharp, R Luben, P Welsh, I Barroso, V Salomaa, A Meirhaeghe, K Khaw, N Sattar, C Langenberg, NJ Wareham. (2011) Mendelian randomization study of B-type natriuretic peptide and type 2 diabetes: evidence of causal association from population studies. PLoS Med 8 (10):e1001112.

R Pfister, SJ Sharp, R Luben, KT Khaw, NJ Wareham. (2011) No evidence of an increased mortality risk associated with low levels of glycated haemoglobin in a non-diabetic UK population. Diabetologia 54 (8):2025-2032.

R Pfister, SJ Sharp, R Luben, NJ Wareham, K Khaw. (2011) Plasma vitamin C predicts incident heart failure in men and women in {Europe}an Prospective Investigation into Cancer and Nutrition-Norfolk prospective study. Am Heart J 162 (2):246-253.

JS Rana, BJ Arsenault, J Despres, M Cote, PJ Talmud, Ewa Ninio, WJ Jukema, NJ Wareham, JJP Kastelein, K Khaw, MS Boekholdt. (2011) Inflammatory biomarkers, physical activity, waist circumference, and risk of future coronary heart disease in healthy men and women. Eur Heart J 32 (3):336-344.

A Ravandi, MS Boekholdt, Z Mallat, PJ Talmud, JJP Kastelein, NJ Wareham, ER Miller, J Benessiano, A Tedgui, JL Witztum, K Khaw, S Tsimikas. (2011) Relationship of IgG and IgM autoantibodies and immune complexes to oxidized LDL with markers of oxidation and inflammation and cardiovascular events: results from the EPIC-Norfolk Study. J Lipid Res 52 (10):1829-1836.

T Johnson, Tom Gaunt, SJ Newhouse, S Padmanabhan, M Tomaszewski, M Kumari, RW Morris, I Tzoulaki, ET OBrien, NR Poulter, P Sever, DC Shields, S Thom, SG Wannamethee, PH Whincup, MJ Brown, JM Connell, RJ Dobson, PJ Howard, CA Mein, A Onipinla, Sue Shaw-Hawkins, Yun Zhang, G Smith, Ian Day, DA Lawlor, AH Goodall, C, Consortium, GF Fowkes, GR Abecasis, P Elliott, V Gateva, G,B Consortium, PS Braund, PR Burton, CP Nelson, MD Tobin, Pim van der Harst, N Glorioso, H Neuvrith, E Salvi, Jan Staessen, A Stucchi, N Devos, X Jeunemaitre, P Plouin, J Tichet, P Juhanson, E Org, M Putku, S Sober, G Veldre, M Viigimaa, A Levinsson, A Rosengren, Dag Thelle, CE Hastie, T Hedner, Wai Lee, O Melander, B Wahlstrand, R Hardy, A Wong, JA Cooper, J Palmen, Li Chen, AFR Stewart, GA Wells, H Westra, MGM Wolfs, R Clarke, M Franzosi, A Goel, A Hamsten, M Lathrop, JF Peden, Udo Seedorf, H Watkins, WH Ouwehand, J Sambrook, J Stephens, J Casas, F Drenos, MV Holmes, M Kivimaki, S Shah, T Shah, PJ Talmud, J Whittaker, C Wallace, C Delles, M Laan, D Kuh, SE Humphries, F Nyberg, D Cusi, R Roberts, C Newton-Cheh, L Franke, AV Stanton, AF Dominiczak, M Farrall, AD Hingorani, NJ Samani, MJ Caulfield, PB Munroe. (2011) Blood pressure loci identified with a gene-centric array. Am J Hum Genet 89 (6):688-700.

Risk Emerging, S Kaptoge, E Angelantonio, G Lowe, MB Pepys, SG Thompson, R Collins, J Danesh. (2010) C-reactive protein concentration and risk of coronary heart disease, stroke, and mortality: an individual participant meta-analysis. Lancet 375 (9709):132-140.

P Chamnan, RK Simmons, K Khaw, NJ Wareham, SJ Griffin. (2010) Estimating the population impact of screening strategies for identifying and treating people at high risk of cardiovascular disease: modelling study. BMJ 340 ():c1693.

RN Freitas, K Khaw, Wu Kelvin, R Bowman, H Jeffery, R Luben, NJ Wareham, S Rodwell. (2010) HMGCR gene polymorphism is associated with stroke risk in the EPIC-Norfolk study. Eur J Cardiovasc Prev Rehabil 17 (1):89-93.

V Gallo, D Neasham, L Airoldi, P Ferrari, M Jenab, P Boffetta, Kim Overvad, A Tjonneland, F Clavel-Chapelon, H Boeing, V Pala, D Palli, S Panico, R Tumino, L Arriola, E Lund, Bueno-De-Mesquita Bas, PH Peeters, O Melander, G Hallmans, E Riboli, R Saracci, P Vineis. (2010) Second-hand Smoke, Cotinine Levels, and Risk of Circulatory Mortality in a Large Cohort Study of Never-Smokers. Epidemiology ():.

JP Casas, Ewa Ninio, A Panayiotou, J Palmen, JA Cooper, SL Ricketts, R Sofat, AN Nicolaides, JP Corsetti, GFR Fowkes, I Tzoulaki, M Kumari, EJ Brunner, M Kivimaki, MG Marmot, MM Hoffmann, K Winkler, W Marz, Ye Shu, HA Stirnadel, MS Boekholdt, K Khaw, SE Humphries, MS Sandhu, AD Hingorani, PJ Talmud. (2010) PLA2G7 genotype, lipoprotein-associated phospholipase A2 activity, and coronary heart disease risk in 10 494 cases and 15 624 controls of {Europe}an Ancestry. Circulation 121 (21):2284-2293.

Coronary Triglyceride, Risk Emerging, N Sarwar, MS Sandhu, SL Ricketts, AS Butterworth, E Angelantonio, MS Boekholdt, W Ouwehand, H Watkins, NJ Samani, D Saleheen, D Lawlor, MP Reilly, AD Hingorani, PJ Talmud, J Danesh. (2010) Triglyceride-mediated pathways and coronary disease: collaborative analysis of 101~{s}tudies. Lancet 375 (9726):1634-1639.

P Chamnan, RK Simmons, H Hori, S Sharp, K Khaw, NJ Wareham, SJ Griffin. (2010) A simple risk score using routine data for predicting cardiovascular disease in primary care. Br J Gen Pract 60 (577):e327-e334.

MS Boekholdt, SM Titan, WM Wiersinga, K Chatterjee, DCG Basart, R Luben, NJ Wareham, K Khaw. (2010) Initial thyroid status and cardiovascular risk factors: the EPIC-Norfolk prospective population study. Clin Endocrinol (Oxf) 72 (3):404-410.

BJ Arsenault, J Despres, ESG Stroes, NJ Wareham, JJP Kastelein, K Khaw, MS Boekholdt. (2010) Lipid assessment, metabolic syndrome and coronary heart disease risk. Eur J Clin Invest ():.

BJ Arsenault, I Lemieux, J Despres, NJ Wareham, JJP Kastelein, K Khaw, MS Boekholdt. (2010) The hypertriglyceridemic-waist phenotype and the risk of coronary artery disease: results from the EPIC-Norfolk prospective population study. CMAJ 182 (13):1427-1432.

BJ Arsenault, I Lemieux, J Despres, NJ Wareham, ESG Stroes, JJP Kastelein, K Khaw, MS Boekholdt. (2010) Comparison between Gradient Gel Electrophoresis and Nuclear Magnetic Resonance Spectroscopy in Estimating Coronary Heart Disease Risk Associated with LDL and {HDL} Particle Size. Clin Chem ():.

BJ Arsenault, JS Rana, I Lemieux, JP Despres, JJP Kastelein, SM Boekholdt, NJ Wareham, KT Khaw. (2010) Physical inactivity, abdominal obesity and risk of coronary heart disease in apparently healthy men and women. Int J Obes (Lond) 34 (2):340-347.

BJ Arsenault, JS Rana, I Lemieux, J Despres, NJ Wareham, JJP Kastelein, MS Boekholdt, K Khaw. (2010) Physical activity, the Framingham risk score and risk of coronary heart disease in men and women of the EPIC-Norfolk study. Atherosclerosis 209 (1):261-265.

C Bamia, J Halkjaer, P Lagiou, D Trichopoulos, A Tjonneland, TL Berentzen, K Overvad, F Clavel-Chapelon, MC Boutron-Ruault, S Rohrmann, J Linseisen, A Steffen, H Boeing, AM May, PH Peeters, Bueno-de-Mesquita Bas, van den Berg, M Dorronsoro, A Barricarte, RL Suarez, C Navarro, CA Gonzalez, P Boffetta, V Pala, G Hallmans, A Trichopoulou. (2010) Weight change in later life and risk of death amongst the elderly: the {Europe}an Prospective Investigation into Cancer and Nutrition-Elderly Network on Ageing and Health study. J Intern Med ():.

S Tsimikas, Z Mallat, PJ Talmud, JJP Kastelein, NJ Wareham, MS Sandhu, ER Miller, J Benessiano, A Tedgui, JL Witztum, K Khaw, MS Boekholdt. (2010) Oxidation-specific biomarkers, lipoprotein(a), and risk of fatal and nonfatal coronary events. J Am Coll Cardiol 56 (12):946-955.

M Vergeer, MS Boekholdt, MS Sandhu, SL Ricketts, NJ Wareham, MJ Brown, Ulf Faire, K Leander, B Gigante, M Kavousi, A Hofman, AG Uitterlinden, CM van Duijn, JCM Witteman, WJ Jukema, EE Schadt, E van der Schoot, JJP Kastelein, K Khaw, RPF Dullaart, A van Tol, MD Trip, GM Dallinga-Thie. (2010) Genetic variation at the phospholipid transfer protein locus affects its activity and high-density lipoprotein size and is a novel marker of cardiovascular disease susceptibility. Circulation 122 (5):470-477.

M Vergeer, DM Cohn, MS Boekholdt, MS Sandhu, HM Prins, SL Ricketts, NJ Wareham, JJP Kastelein, K Khaw, PW Kamphuisen, GM Dallinga-Thie. (2010) Lack of association between common genetic variation in endothelial lipase (LIPG) and the risk for {CAD} and DVT. Atherosclerosis ():.

PG Surtees, NWJ Wainwright, R Luben, NJ Wareham, SA Bingham, K Khaw. (2010) Mastery is associated with cardiovascular disease mortality in men and women at apparently low risk. Health Psychol 29 (4):412-420.

S Sivapalaratnam, MS Boekholdt, MD Trip, MS Sandhu, R Luben, JJP Kastelein, NJ Wareham, K Khaw. (2010) Family history of premature coronary heart disease and risk prediction in the EPIC-Norfolk prospective population study. Heart ():.

DM Waterworth, SL Ricketts, K Song, Li Chen, J Zhao, S Ripatti, YS Aulchenko, W Zhang, Xin Yuan, N Lim, J Luan, S Ashford, E Wheeler, EH Young, D Hadley, JR Thompson, PS Braund, T Johnson, M Struchalin, Ida Surakka, R Luben, K Khaw, SA Rodwell, RJF Loos, MS Boekholdt, M Inouye, P Deloukas, P Elliott, D Schlessinger, S Sanna, A Scuteri, A Jackson, KL Mohlke, J Tuomilehto, R Roberts, A Stewart, AY Kesaniemi, RW Mahley, SM Grundy, Trust Wellcome, W McArdle, Lon Cardon, G Waeber, P Vollenweider, JC Chambers, M Boehnke, GR Abecasis, V Salomaa, M Jarvelin, A Ruokonen, I Barroso, SE Epstein, HH Hakonarson, DJ Rader, MP Reilly, JCM Witteman, AS Hall, NJ Samani, DP Strachan, P Barter, CM van Duijn, JS Kooner, L Peltonen, NJ Wareham, R McPherson, V Mooser, MS Sandhu. (2010) Genetic variants influencing circulating lipid levels and risk of coronary artery disease. Arterioscler Thromb Vasc Biol 30 (11):2264-2276.

DF van Wijk, SI van Leuven, MS Sandhu, MW Tanck, BA Hutten, NJ Wareham, JJP Kastelein, ESG Stroes, K Khaw, MS Boekholdt. (2010) Chemokine ligand 2 genetic variants, serum monocyte chemoattractant protein-1 levels, and the risk of coronary artery disease. Arterioscler Thromb Vasc Biol 30 (7):1460-1466.

TM Teslovich, K Musunuru, AV Smith, AC Edmondson, IM Stylianou, M Koseki, JP Pirruccello, S Ripatti, DI Chasman, CJ Willer, CT Johansen, SW Fouchier, A Isaacs, GM Peloso, M Barbalic, SL Ricketts, JC Bis, YS Aulchenko, G Thorleifsson, MF Feitosa, J Chambers, M Orho-Melander, O Melander, T Johnson, Li Xiaohui, X Guo, Li Mingyao, Y Cho, Min Jin, Y Kim, J Lee, T Park, K Kim, X Sim, R Ong, DC Croteau-Chonka, LA Lange, JD Smith, K Song, J Zhao, Xin Yuan, J Luan, C Lamina, A Ziegler, W Zhang, RYL Zee, AF Wright, JCM Witteman, JF Wilson, G Willemsen, Wichmann H-Erich, JB Whitfield, DM Waterworth, NJ Wareham, G Waeber, P Vollenweider, BF Voight, V Vitart, AG Uitterlinden, M Uda, J Tuomilehto, JR Thompson, T Tanaka, Ida Surakka, HM Stringham, Tim Spector, N Soranzo, JH Smit, J Sinisalo, K Silander, EJG Sijbrands, A Scuteri, J Scott, D Schlessinger, S Sanna, V Salomaa, J Saharinen, C Sabatti, A Ruokonen, I Rudan, LM Rose, R Roberts, M Rieder, BM Psaty, PP Pramstaller, I Pichler, M Perola, BWJH Penninx, NL Pedersen, C Pattaro, AN Parker, G Pare, Ben Oostra, CJ ODonnell, MS Nieminen, DA Nickerson, GW Montgomery, T Meitinger, R McPherson, MI McCarthy, W McArdle, D Masson, NG Martin, F Marroni, M Mangino, PKE Magnusson, G Lucas, R Luben, RJF Loos, M Lokki, G Lettre, C Langenberg, LJ Launer, EG Lakatta, R Laaksonen, KO Kyvik, F Kronenberg, IR Konig, K Khaw, J Kaprio, Lee Kaplan, Asa Johansson, M Jarvelin, CAJW Janssens, E Ingelsson, W Igl, KG Hovingh, J Hottenga, A Hofman, AA Hicks, C Hengstenberg, IM Heid, C Hayward, Aki Havulinna, ND Hastie, TB Harris, T Haritunians, AS Hall, Ulf Gyllensten, C Guiducci, LC Groop, E Gonzalez, C Gieger, NB Freimer, L Ferrucci, J Erdmann, P Elliott, KG Ejebe, A Doring, AF Dominiczak, S Demissie, P Deloukas, Eco Geus, Ulf Faire, G Crawford, FS Collins, YI Chen, MJ Caulfield, H Campbell, NP Burtt, LL Bonnycastle, DI Boomsma, MS Boekholdt, RN Bergman, I Barroso, S Bandinelli, CM Ballantyne, TL Assimes, T Quertermous, D Altshuler, M Seielstad, TY Wong, Tai E-Shyong, AB Feranil, CW Kuzawa, LS Adair, HA Taylor, IB Borecki, SB Gabriel, JG Wilson, H Holm, U Thorsteinsdottir, V Gudnason, RM Krauss, KL Mohlke, JM Ordovas, PB Munroe, JS Kooner, AR Tall, RA Hegele, JJP Kastelein, EE Schadt, JI Rotter, E Boerwinkle, DP Strachan, V Mooser, K Stefansson, MP Reilly, J Nilesh. (2010) Biological, clinical and population relevance of 95 loci for blood lipids. Nature 466 (7307):707-713.

MC Smart-Halajko, MR Robciuc, JA Cooper, M Jauhiainen, M Kumari, M Kivimaki, K Khaw, MS Boekholdt, NJ Wareham, Tom Gaunt, Ian Day, PS Braund, CP Nelson, AS Hall, NJ Samani, SE Humphries, C Ehnholm, PJ Talmud. (2010) The relationship between plasma angiopoietin-like protein 4 levels, angiopoietin-like protein 4 genotype, and coronary heart disease risk. Arterioscler Thromb Vasc Biol 30 (11):2277-2282.

N Rodondi, WPJ den Elzen, DC Bauer, AR Cappola, S Razvi, JP Walsh, BO Asvold, G Iervasi, M Imaizumi, T Collet, A Bremner, P Maisonneuve, JA Sgarbi, K Khaw, MPJ Vanderpump, AB Newman, J Cornuz, JA Franklyn, RGJ Westendorp, E Vittinghoff, J Gussekloo, T Collaboration. (2010) Subclinical hypothyroidism and the risk of coronary heart disease and mortality. JAMA 304 (12):1365-1374.

PK Myint, RN Luben, PG Surtees, NWJ Wainwright, NJ Wareham, K Khaw. (2010) Physical functional health predicts the incidence of coronary heart disease in the {Europe}an Prospective Investigation into Cancer-Norfolk prospective population-based study. Int J Epidemiol 39 (4):996-1003.

JS Rana, ME Visser, BJ Arsenault, J Despres, ESG Stroes, JJP Kastelein, NJ Wareham, MS Boekholdt, K Khaw. (2010) Metabolic dyslipidemia and risk of future coronary heart disease in apparently healthy men and women: the EPIC-Norfolk prospective population study. Int J Cardiol 143 (3):399-404.

PK Myint, RD Smith, RN Luben, PG Surtees, NWJ Wainwright, NJ Wareham, SA Bingham, K Khaw. (2010) The Short-Form Six-Dimension utility index predicted mortality in the {Europe}an Prospective Investigation into Cancer-Norfolk prospective population-based study. J Clin Epidemiol 63 (2):192-198.

LpPLA2SC, T Alexander, Gao Pei, O Lia, W Sarah, A Emanuele, K Stephen, B Christie, CP Christopher, C Michael, C Mary, H Albert, P Chris, TG Simon, C Rory, D John. (2010) Lipoprotein-associated phospholipase A(2) and risk of coronary disease, stroke, and mortality: collaborative analysis of 32 prospective studies. Lancet 375 (9725):1536-1544.

ERFC, S N., G P., K S., G R., K S., A E., I E., L D., S E., S M., S C., L S., P L., T A., S N., W I., R K., D J.. (2010) Diabetes mellitus, fasting blood glucose concentration, and risk of vascular disease: a collaborative meta-analysis of 102 prospective studies. Lancet 375 (9733):2215-2222.

AG Holleboom, JA Kuivenhoven, M Vergeer, GK Hovingh, van Miert, NJ Wareham, JJP Kastelein, KT Khaw, SM Boekholdt. (2010) Plasma levels of lecithin:cholesterol acyltransferase and risk of future coronary artery disease in apparently healthy men and women: a prospective case-control analysis nested in the EPIC-Norfolk population study. J Lipid Res 51 (2):416-421.

KM Ikram, X Sim, Sim Xueling, RA Jensen, M Cotch, AW Hewitt, AM Ikram, J Wang, R Klein, BEK Klein, MMB Breteler, N Cheung, G Liew, P Mitchell, AG Uitterlinden, F Rivadeneira, A Hofman, PTVM Jong, CM van Duijn, L Kao, C Cheng, A Smith, NL Glazer, T Lumley, B McKnight, BM Psaty, F Jonasson, G Eiriksdottir, T Aspelund, G Consortium, TB Harris, LJ Launer, KD Taylor, Li Xiaohui, SK Iyengar, Xi Quansheng, TA Sivakumaran, DA Mackey, S Macgregor, NG Martin, TL Young, JC Bis, KL Wiggins, SR Heckbert, CJ Hammond, T Andrew, S Fahy, J Attia, EG Holliday, RJ Scott, AFM Islam, JI Rotter, AK McAuley, E Boerwinkle, SE Tai, V Gudnason, DS Siscovick, JR Vingerling, TY Wong. (2010) Four novel Loci (19q13, 6q24, 12q24, and 5q14) influence the microcirculation in vivo. PLoS Genet 6 (10):e1001184.

Risk Emerging, E Angelantonio, N Sarwar, P Perry, S Kaptoge, KK Ray, A Thompson, AM Wood, S Lewington, N Sattar, CJ Packard, R Collins, SG Thompson, J Danesh. (2009) Major lipids, apolipoproteins, and risk of vascular disease. JAMA 302 (18):1993-2000.

RS Birjmohun, M Vergeer, ESG Stroes, MS Sandhu, SL Ricketts, MW Tanck, NJ Wareham, WJ Jukema, JJP Kastelein, K Khaw, MS Boekholdt. (2009) Both paraoxonase-1 genotype and activity do not predict the risk of future coronary artery disease; the EPIC-Norfolk Prospective Population Study. PLoS One 4 (8):e6809.

R Bowman, A Joosen, AA Welch, RN Luben, KT Khaw, NJ Wareham, SA Bingham. (2009) Factor VII, blood lipids and fat intake: gene-nutrient interaction and risk of coronary heart disease with the factor VII R353Q polymorphism. Eur J Clin Nutr 63 (6):771-777.

BJ Arsenault, I Lemieux, J Despres, P Gagnon, NJ Wareham, ESG Stroes, JJP Kastelein, K Khaw, MS Boekholdt. (2009) {HDL} particle size and the risk of coronary heart disease in apparently healthy men and women: The EPIC-Norfolk prospective population study. Atherosclerosis ():.

BJ Arsenault, JS Rana, ESG Stroes, J Despres, PK Shah, JJP Kastelein, NJ Wareham, MS Boekholdt, K Khaw. (2009) Beyond Low-Density Lipoprotein Cholesterol Respective Contributions of Non-High-Density Lipoprotein Cholesterol Levels, Triglycerides, and the Total Cholesterol/High-Density Lipoprotein Cholesterol Ratio to Coronary Heart Disease Risk in Apparently Healthy Men and Women. J Am Coll Cardiol 55 (1):35-41.

H Ward, PN Mitrou, R Bowman, R Luben, NJ Wareham, K Khaw, S Bingham. (2009) APOE genotype, lipids, and coronary heart disease risk: a prospective population study. Arch Intern Med 169 (15):1424-1429.

RK Simmons, RL Coleman, HC Price, RR Holman, K Khaw, NJ Wareham, SJ Griffin. (2009) Performance of the UK Prospective Diabetes Study Risk Engine and the Framingham Risk Equations in Estimating Cardiovascular Disease in the EPIC- Norfolk Cohort. Diabetes Care 32 (4):708-713.

AG Semb, T Ueland, P Aukrust, NJ Wareham, R Luben, L Gullestad, JJP Kastelein, K Khaw, MS Boekholdt. (2009) Osteoprotegerin and soluble receptor activator of nuclear factor-kappaB ligand and risk for coronary events: a nested case-control approach in the prospective EPIC-Norfolk population study 1993-2003. Arterioscler Thromb Vasc Biol 29 (6):975-980.

PK Myint, RN Luben, NJ Wareham, SA Bingham, K Khaw. (2009) Combined effect of health behaviours and risk of first ever stroke in 20,040~{m}en and women over 11 years' follow-up in Norfolk cohort of {Europe}an Prospective Investigation of Cancer (EPIC Norfolk): prospective population study. BMJ 338 ():b349.

JS Rana, M Cote, JP Despres, MS Sandhu, PJ Talmud, E Ninio, NJ Wareham, JJP Kastelein, AH Zwinderman, KT Khaw, SM Boekholdt. (2009) Inflammatory biomarkers and the prediction of coronary events among people at intermediate risk; the EPIC-Norfolk prospective population study. Heart ():.

AQ Reuwer, ThB Marcel, BA Hutten, FW Molema, NJ Wareham, GM Dallinga-Thie, RL Bogorad, V Goffin, M Smink-Bol, JJP Kastelein, MS Boekholdt, K Khaw. (2009) Prolactin levels and the risk of future coronary artery disease in apparently healthy men and women. Circ Cardiovasc Genet 2 (4):389-395.

C Newton-Cheh, T Johnson, V Gateva, MD Tobin, M Bochud, L Coin, SS Najjar, J Zhao, SC Heath, S Eyheramendy, K Papadakis, BF Voight, LJ Scott, F Zhang, M Farrall, T Tanaka, C Wallace, JC Chambers, K Khaw, P Nilsson, Pim van der Harst, S Polidoro, DE Grobbee, CN Onland-Moret, ML Bots, LV Wain, KS Elliott, A Teumer, J Luan, G Lucas, J Kuusisto, PR Burton, D Hadley, WL McArdle, Trust Wellcome, M Brown, A Dominiczak, SJ Newhouse, NJ Samani, J Webster, E Zeggini, JS Beckmann, S Bergmann, N Lim, K Song, P Vollenweider, G Waeber, DM Waterworth, Xin Yuan, L Groop, M Orho-Melander, A Allione, A Gregorio, S Guarrera, S Panico, F Ricceri, V Romanazzi, C Sacerdote, P Vineis, I Barroso, MS Sandhu, RN Luben, GJ Crawford, P Jousilahti, M Perola, M Boehnke, LL Bonnycastle, FS Collins, AU Jackson, KL Mohlke, HM Stringham, TT Valle, CJ Willer, RN Bergman, MA Morken, A Doring, C Gieger, T Illig, T Meitinger, E Org, A Pfeufer, EH Wichmann, S Kathiresan, J Marrugat, CJ ODonnell, SM Schwartz, DS Siscovick, I Subirana, NB Freimer, A Hartikainen, MI McCarthy, PF OReilly, L Peltonen, A Pouta, PE Jong, H Snieder, WH van Gilst, R Clarke, A Goel, A Hamsten, JF Peden, Udo Seedorf, A Syvanen, G Tognoni, EG Lakatta, S Sanna, P Scheet, D Schlessinger, A Scuteri, M Dorr, F Ernst, SB Felix, G Homuth, R Lorbeer, T Reffelmann, R Rettig, Uwe Volker, P Galan, Ivo Gut, S Hercberg, MG Lathrop, D Zelenika, P Deloukas, N Soranzo, FM Williams, G Zhai, V Salomaa, M Laakso, R Elosua, NG Forouhi, H Volzke, CS Uiterwaal, YT van der Schouw, ME Numans, G Matullo, G Navis, G Berglund, SA Bingham, JS Kooner, JM Connell, S Bandinelli, L Ferrucci, H Watkins, Tim Spector, J Tuomilehto, D Altshuler, DP Strachan, M Laan, P Meneton, NJ Wareham, M Uda, M Jarvelin, V Mooser, O Melander, R Loos, P Elliott, GR Abecasis, M Caulfield, PB Munroe. (2009) Genome-wide association study identifies eight loci associated with blood pressure. Nat Genet ():.

Z Mallat, T Simon, J Benessiano, K Clement, S Taleb, NJ Wareham, R Luben, K Khaw, A Tedgui, MS Boekholdt. (2009) Retinol-binding protein 4 and prediction of incident coronary events in healthy men and women. J Clin Endocrinol Metab 94 (1):255-260.

R Lakshman, NG Forouhi, SJ Sharp, R Luben, SA Bingham, K Khaw, NJ Wareham, Ken Ong. (2009) Early age at menarche associated with cardiovascular disease and mortality. J Clin Endocrinol Metab 94 (12):4953-4960.

K Harchaoui, BJ Arsenault, R Franssen, J Despres, KG Hovingh, ESG Stroes, JD Otvos, NJ Wareham, JJP Kastelein, K Khaw, MS Boekholdt. (2009) High-density lipoprotein particle size and concentration and coronary risk. Ann Intern Med 150 (2):84-93.

H Besson, Ulf Ekelund, S Brage, R Luben, S Bingham, K Khaw, N Wareham. (2008) Relationship between Subdomains of Total Physical Activity and Mortality. Med Sci Sports Exerc ():.

S Bingham, R Luben, A Welch, Y Low, K Khaw, N Wareham, N Day. (2008) Associations between dietary methods and biomarkers, and between fruits and vegetables and risk of ischaemic heart disease, in the EPIC Norfolk Cohort Study. Int J Epidemiol ():.

J Wang, R Luben, K Khaw, S Bingham, NJ Wareham, NG Forouhi. (2008) Dietary energy density predicts the risk of incident type 2 diabetes: the {Europe}an Prospective Investigation of Cancer (EPIC)-Norfolk Study. Diabetes Care 31 (11):2120-2125.

RK Simmons, S Sharp, MS Boekholdt, LA Sargeant, K Khaw, NJ Wareham, SJ Griffin. (2008) Evaluation of the Framingham risk score in the {Europe}an Prospective Investigation of Cancer-Norfolk cohort: does adding glycated hemoglobin improve the prediction of coronary heart disease events? Arch Intern Med 168 (11):1209-1216.

PG Surtees, NWJ Wainwright, RN Luben, NJ Wareham, SA Bingham, K Khaw. (2008) Depression and ischemic heart disease mortality: evidence from the EPIC-Norfolk {United Kingdom} prospective cohort study. Am J Psychiatry 165 (4):515-523.

PG Surtees, NWJ Wainwright, RN Luben, NJ Wareham, SA Bingham, KT Khaw. (2008) Psychological distress, major depressive disorder, and risk of stroke. Neurology 70 (10):788-794.

AA Welch, SA Bingham, KT Khaw. (2008) Estimated conversion of alpha-linolenic acid to long chain n-3 polyunsaturated fatty acids is greater than expected in non fish-eating vegetarians and non fish-eating meat-eaters than in fish-eaters. J Hum Nutr Diet 21 (4):404.

Wim van der Steeg, I Holme, MS Boekholdt, M Larsen, C Lindahl, ESG Stroes, MJ Tikkanen, NJ Wareham, Ole Faergeman, AG Olsson, TR Pedersen, K Khaw, JJP Kastelein. (2008) High-density lipoprotein cholesterol, high-density lipoprotein particle size, and apolipoprotein A-I: significance for cardiovascular risk: the IDEAL and EPIC-Norfolk studies. J Am Coll Cardiol 51 (6):634-642.

PG Surtees, NWJ Wainwright, MS Boekholdt, RN Luben, NJ Wareham, K Khaw. (2008) Major Depression, C-Reactive Protein, and Incident Ischemic Heart Disease in Healthy Men and Women. Psychosom Med ():.

MS Sandhu, DM Waterworth, SL Debenham, E Wheeler, K Papadakis, J Zhao, K Song, Xin Yuan, T Johnson, S Ashford, M Inouye, R Luben, M Sims, D Hadley, W McArdle, P Barter, AY Kesaniemi, RW Mahley, R McPherson, SM Grundy, Trust Wellcome, SA Bingham, K Khaw, RJF Loos, G Waeber, I Barroso, DP Strachan, P Deloukas, P Vollenweider, NJ Wareham, V Mooser. (2008) LDL-cholesterol concentrations: a genome-wide association study. Lancet 371 (9611):483-491.

MJ Pencina, RB DAgostino. (2008) Evaluation of the Framingham risk score in the {Europe}an Prospective Investigation of Cancer-Norfolk cohort--invited commentary. Arch Intern Med 168 (11):1216-1218.

PK Myint, RN Luben, NJ Wareham, AA Welch, SA Bingham, K Khaw. (2008) Physical activity and fibrinogen concentrations in 23,201~{m}en and women in the EPIC-Norfolk population-based study. Atherosclerosis 198 (2):419-425.

PK Myint, RN Luben, AA Welch, SA Bingham, NJ Wareham, K Khaw. (2008) Plasma vitamin C concentrations predict risk of incident stroke over 10 y in 20 649 participants of the {Europe}an Prospective Investigation into Cancer Norfolk prospective population study. Am J Clin Nutr 87 (1):64-69.

Ute Nothlings, MB Schulze, C Weikert, H Boeing, YT van der Schouw, C Bamia, V Benetou, P Lagiou, V Krogh, JWJ Beulens, PHM Peeters, J Halkjaer, A Tjonneland, R Tumino, S Panico, G Masala, F Clavel-Chapelon, B Lauzon, M Boutron-Ruault, M Vercambre, R Kaaks, J Linseisen, Kim Overvad, L Arriola, Eva Ardanaz, CA Gonzalez, M Tormo, S Bingham, K Khaw, Tim Key, P Vineis, E Riboli, P Ferrari, P Boffetta, Bueno-de-Mesquita Bas, DLA van der, G Berglund, E Wirfalt, G Hallmans, I Johansson, E Lund, A Trichopoulo. (2008) Intake of vegetables, legumes, and fruit, and risk for all-cause, cardiovascular, and cancer mortality in a {Europe}an diabetic population. J Nutr 138 (4):775-781.

E McFadden, R Luben, N Wareham, S Bingham, K Khaw. (2008) Occupational social class, educational level, smoking and body mass index, and cause-specific mortality in men and women: a prospective study in the {Europe}an Prospective Investigation of Cancer and Nutrition in Norfolk (EPIC-Norfolk) cohort. Eur J Epidemiol 23 (8):511-522.

E McFadden, R Luben, N Wareham, S Bingham, K Khaw. (2008) Occupational social class, risk factors and cardiovascular disease incidence in men and women: a prospective study in the {Europe}an Prospective Investigation of Cancer and Nutrition in Norfolk (EPIC-Norfolk) cohort. Eur J Epidemiol 23 (7):449-458.

K Khaw, N Wareham, S Bingham, A Welch, R Luben, N Day. (2008) Combined impact of health behaviours and mortality in men and women: the EPIC-Norfolk prospective population study. PLoS Med 5 (1):e12.

RS Birjmohun, GM Dallinga-Thie, J Kuivenhoven, ESG Stroes, JD Otvos, NJ Wareham, R Luben, JJP Kastelein, K Khaw, MS Boekholdt. (2007) Apolipoprotein A-II is inversely associated with risk of future coronary artery disease. Circulation 116 (18):2029-2035.

BJ Arsenault, I Lemieux, J Despres, NJ Wareham, R Luben, JJP Kastelein, K Khaw, MS Boekholdt. (2007) Cholesterol levels in small LDL particles predict the risk of coronary heart disease in the EPIC-Norfolk prospective population study. Eur Heart J 28 (22):2770-2777.

C Bamia, D Trichopoulos, P Ferrari, Kim Overvad, L Bjerregaard, A Tjonneland, J Halkjaer, F Clavel-Chapelon, E Kesse, M Boutron-Ruault, P Boffetta, G Nagel, J Linseisen, H Boeing, K Hoffmann, C Kasapa, A Orfanou, C Travezea, N Slimani, T Norat, D Palli, V Pala, S Panico, R Tumino, C Sacerdote, Bueno-de-Mesquita Bas, PMCM Waijers, PHM Peeters, YT van der Schouw, A Berenguer, C Martinez-Garcia, C Navarro, A Barricarte, M Dorronsoro, G Berglund, E Wirfalt, I Johansson, G Johansson, S Bingham, K Khaw, EA Spencer, Tim Key, E Riboli, A Trichopoulou. (2007) Dietary patterns and survival of older {Europe}ans: the EPIC-Elderly Study ({Europe}an Prospective Investigation into Cancer and Nutrition). Public Health Nutr 10 (6):590-598.

Wu Kelvin, R Bowman, AA Welch, RN Luben, N Wareham, K Khaw, SA Bingham. (2007) Apolipoprotein E polymorphisms, dietary fat and fibre, and serum lipids: the EPIC Norfolk study. Eur Heart J 28 (23):2930-2936.

NWJ Wainwright, PG Surtees, NJ Wareham, BDW Harrison. (2007) Psychosocial factors and asthma in a community sample of older adults. J Psychosom Res 62 (3):357-361.

A Trichopoulou, C Bamia, T Norat, K Overvad, EB Schmidt, A Tjonneland, J Halkjaer, F Clavel-Chapelon, MN Vercambre, MC Boutron-Ruault, J Linseisen, S Rohrmann, H Boeing, C Weikert, V Benetou, T Psaltopoulou, P Orfanos, P Boffetta, G Masala, V Pala, S Panico, R Tumino, C Sacerdote, H Bueno-de-Mesquita, MC Ocke, PH Peeters, VYT Schouw, C Gonzalez, MJ Sanchez, MD Chirlaque, C Moreno, N Larranaga, Van Guelpen, JH Jansson, S Bingham, KT Khaw, EA Spencer, T Key, E Riboli, D Trichopoulos. (2007) Modified Mediterranean diet and survival after myocardial infarction: the EPIC-Elderly study. Eur J Epidemiol 22 (12):871-881.

Wim van der Steeg, MS Boekholdt, EA Stein, K El-Harchaoui, ESG Stroes, MS Sandhu, NJ Wareham, WJ Jukema, R Luben, AH Zwinderman, JJP Kastelein, K Khaw. (2007) Role of the apolipoprotein B-apolipoprotein A-I ratio in cardiovascular risk assessment: a case-control analysis in EPIC-Norfolk. Ann Intern Med 146 (9):640-648.

S Pinedo, MN Vissers, K von Bergmann, K Elharchaoui, D Lutjohann, R Luben, NJ Wareham, JJP Kastelein, K Khaw, MS Boekholdt. (2007) Plasma levels of plant sterols and the risk of coronary artery disease: the prospective EPIC-Norfolk Population Study. J Lipid Res 48 (1):139-144.

N Sarwar, J Danesh, G Eiriksdottir, G Sigurdsson, N Wareham, S Bingham, MS Boekholdt, K Khaw, V Gudnason. (2007) Triglycerides and the risk of coronary heart disease: 10,158 incident cases among 262,525 participants in 29~{W}estern prospective studies. Circulation 115 (4):450-458.

PK Myint, RN Luben, PG Surtees, NWJ Wainwright, AA Welch, SA Bingham, NJ Wareham, RD Smith, Ian Harvey, K Khaw. (2007) Self-reported mental health-related quality of life and mortality in men and women in the {Europe}an Prospective Investigation into Cancer (EPIC-Norfolk): a prospective population study. Psychosom Med 69 (5):410-414.

JS Rana, SM Boekholdt, PM Ridker, JW Jukema, R Luben, SA Bingham, NE Day, NJ Wareham, JJP Kastelein, KT Khaw. (2007) Differential leucocyte count and the risk of future coronary artery disease in healthy men and women: the EPIC-Norfolk Prospective Population Study. J Intern Med 262 (6):678-689.

PK Myint, S Sinha, NJ Wareham, SA Bingham, RN Luben, AA Welch, K Khaw. (2007) Glycated hemoglobin and risk of stroke in people without known diabetes in the {Europe}an Prospective Investigation into Cancer (EPIC)-Norfolk prospective population study: a threshold relationship? Stroke 38 (2):271-275.

PK Myint, PG Surtees, NWJ Wainwright, RN Luben, AA Welch, SA Bingham, NJ Wareham, KT Khaw. (2007) Physical health-related quality of life predicts stroke in the EPIC-Norfolk. Neurology 69 (24):2243-2248.

MC Meuwese, ESG Stroes, SL Hazen, JN van Miert, J Kuivenhoven, RG Schaub, NJ Wareham, R Luben, JJP Kastelein, K Khaw, MS Boekholdt. (2007) Serum myeloperoxidase levels are associated with the future risk of coronary artery disease in apparently healthy individuals: the EPIC-Norfolk Prospective Population Study. J Am Coll Cardiol 50 (2):159-165.

Z Mallat, J Benessiano, T Simon, S Ederhy, C Sebella-Arguelles, A Cohen, V Huart, NJ Wareham, R Luben, K Khaw, A Tedgui, MS Boekholdt. (2007) Circulating secretory phospholipase A2 activity and risk of incident coronary events in healthy men and women: the EPIC-Norfolk study. Arterioscler Thromb Vasc Biol 27 (5):1177-1183.

K Harchaoui, Wim van der Steeg, ESG Stroes, J Kuivenhoven, JD Otvos, NJ Wareham, BA Hutten, JJP Kastelein, K Khaw, MS Boekholdt. (2007) Value of low-density lipoprotein particle number and size as predictors of coronary artery disease in apparently healthy men and women: the EPIC-Norfolk Prospective Population Study. J Am Coll Cardiol 49 (5):547-553.

B Heude, Ken Ong, R Luben, NJ Wareham, MS Sandhu. (2007) Study of association between common variation in the insulin-like growth factor 2 gene and indices of obesity and body size in middle-aged men and women. J Clin Endocrinol Metab 92 (7):2734-2738.

K Khaw, M Dowsett, E Folkerd, S Bingham, N Wareham, R Luben, A Welch, N Day. (2007) Endogenous testosterone and mortality due to all causes, cardiovascular disease, and cancer in men: {Europe}an prospective investigation into cancer in Norfolk (EPIC-Norfolk) Prospective Population Study. Circulation 116 (23):2694-2701.

J Danesh, R Saracci, G Berglund, E Feskens, Kim Overvad, S Panico, S Thompson, A Fournier, F Clavel-Chapelon, M Canonico, R Kaaks, J Linseisen, H Boeing, T Pischon, C Weikert, A Olsen, A Tjonneland, S Johnsen, M Jensen, JR Quiros, Alberto Carlos, M Perez, N Larranaga, C Sanchez, C Iribas, S Bingham, K Khaw, N Wareham, T Key, A Roddam, A Trichopoulou, V Benetou, D Trichopoulos, G Masala, S Sieri, R Tumino, C Sacerdote, A Mattiello, MWM Verschuren, Bueno-de-Mesquita Bas, DE Grobbee, YT van der Schouw, O Melander, G Hallmans, P Wennberg, E Lund, M Kumle, G Skeie, P Ferrari, N Slimani, T Norat, E Riboli, E C-Heart. (2007) EPIC-Heart: the cardiovascular component of a prospective study of nutritional, lifestyle and biological factors in 520,000~{m}iddle-aged participants from 10 {Europe}an countries. Eur J Epidemiol 22 (2):129-141.

D Canoy, MS Boekholdt, N Wareham, R Luben, A Welch, S Bingham, I Buchan, N Day, K Khaw. (2007) Body fat distribution and risk of coronary heart disease in men and women in the {Europe}an Prospective Investigation Into Cancer and Nutrition in Norfolk cohort: a population-based prospective study. Circulation 116 (25):2933-2943.

K Khaw, N Wareham. (2006) Glycated hemoglobin as a marker of cardiovascular risk. Curr Opin Lipidol 17 (6):637-643.

D Canoy, N Wareham, R Luben, A Welch, S Bingham, N Day, K Khaw. (2006) Serum lipid concentration in relation to anthropometric indices of central and peripheral fat distribution in 20,021~{B}ritish men and women: results from the EPIC-Norfolk population-based cohort study. Atherosclerosis 189 (2):420-427.

D Drogan, K Klipstein-Grobusch, J Dierkes, C Weikert, H Boeing. (2006) Dietary intake of folate equivalents and risk of myocardial infarction in the {Europe}an Prospective Investigation into Cancer and Nutrition (EPIC)--Potsdam study. Public Health Nutr 9 (4):465-471.

MS Boekholdt, EC Hack, MS Sandhu, R Luben, SA Bingham, NJ Wareham, Ron Peters, WJ Jukema, NE Day, JJP Kastelein, K Khaw. (2006) C-reactive protein levels and coronary artery disease incidence and mortality in apparently healthy men and women: the EPIC-Norfolk prospective population study 1993-2003. Atherosclerosis 187 (2):415-422.

MS Boekholdt, MS Sandhu, NE Day, R Luben, SA Bingham, Ron Peters, NJ Wareham, K Khaw. (2006) Physical activity, C-reactive protein levels and the risk of future coronary artery disease in apparently healthy men and women: the EPIC-Norfolk prospective population study. Eur J Cardiovasc Prev Rehabil 13 (6):970-976.

SM Boekholdt, MS Sandhu, NJ Wareham, R Luben, PH Reitsma, KT Khaw. (2006) Fibrinogen plasma levels modify the association between the factor XIII Val34Leu variant and risk of coronary artery disease: the EPIC-Norfolk prospective population study. J Thromb Haemost 4 (10):2204-2209.

MS Boekholdt, MC Meuwese, NE Day, R Luben, A Welch, NJ Wareham, K Khaw. (2006) Plasma concentrations of ascorbic acid and C-reactive protein, and risk of future coronary artery disease, in apparently healthy men and women: the EPIC-Norfolk prospective population study. Br J Nutr 96 (3):516-522.

A Trichopoulou, T Psaltopoulou, P Orfanos, D Trichopoulos. (2006) Diet and physical activity in relation to overall mortality amongst adult diabetics in a general population cohort. J Intern Med 259 (6):583-591.

SFC Vaessen, FG Schaap, J Kuivenhoven, AK Groen, BA Hutten, MS Boekholdt, H Hattori, MS Sandhu, SA Bingham, R Luben, JA Palmen, NJ Wareham, SE Humphries, JJP Kastelein, PJ Talmud, K Khaw. (2006) Apolipoprotein A-V, triglycerides and risk of coronary artery disease: the prospective Epic-Norfolk Population Study. J Lipid Res 47 (9):2064-2070.

PG Surtees, NWJ Wainwright, R Luben, K Khaw, NE Day. (2006) Mastery, sense of coherence, and mortality: evidence of independent associations from the EPIC-Norfolk Prospective Cohort Study. Health Psychol 25 (1):102-110.

AA Welch, SA Bingham, J Ive, MD Friesen, NJ Wareham, E Riboli, KT Khaw. (2006) Dietary fish intake and plasma phospholipid n-3 polyunsaturated fatty acid concentrations in men and women in the {Europe}an Prospective Investigation into Cancer-Norfolk {United Kingdom} cohort. Am J Clin Nutr 84 (6):1330-1339.

J Rip, MC Nierman, NJ Wareham, R Luben, SA Bingham, NE Day, JNI van Miert, BA Hutten, JJP Kastelein, J Kuivenhoven, K Khaw, MS Boekholdt. (2006) Serum lipoprotein lipase concentration and risk for future coronary artery disease: the EPIC-Norfolk prospective population study. Arterioscler Thromb Vasc Biol 26 (3):637-642.

V Pala, S Sieri, G Masala, D Palli, S Panico, P Vineis, C Sacerdote, A Mattiello, R Galasso, S Salvini, M Ceroti, F Berrino, E Fusconi, R Tumino, G Frasca, E Riboli, A Trichopoulou, N Baibas, V Krogh. (2006) Associations between dietary pattern and lifestyle, anthropometry and other health indicators in the elderly participants of the EPIC-{Italy} cohort. Nutr Metab Cardiovasc Dis 16 (3):186-201.

PK Myint, RN Luben, PG Surtees, NWJ Wainwright, AA Welch, SA Bingham, NE Day, NJ Wareham, K Khaw. (2006) Relation between self-reported physical functional health and chronic disease mortality in men and women in the {Europe}an Prospective Investigation into Cancer (EPIC-Norfolk): a prospective population study. Ann Epidemiol 16 (6):492-500.

PK Myint, RN Luben, NJ Wareham, AA Welch, SA Bingham, NE Day, K Khaw. (2006) Combined work and leisure physical activity and risk of stroke in men and women in the {Europe}an prospective investigation into Cancer-Norfolk Prospective Population Study. Neuroepidemiology 27 (3):122-129.

PK Myint, RN Luben, AA Welch, SA Bingham, NJ Wareham, K Khaw. (2006) Effect of age on the relationship of occupational social class with prevalence of modifiable cardiovascular risk factors and cardiovascular diseases. A population-based cross-sectional study from {Europe}an Prospective Investigation into Cancer - Norfolk (EPIC-Norfolk). Gerontology 52 (1):51-58.

PK Myint, AA Welch, SA Bingham, RN Luben, NJ Wareham, NE Day, K Khaw. (2006) Smoking predicts long-term mortality in stroke: The {Europe}an Prospective Investigation into Cancer (EPIC)-Norfolk prospective population study. Prev Med 42 (2):128-131.

AHEM Maas, YT van der Schouw, D Beijerinck, Jan Deurenberg, WPTM Mali, Y van der Graaf. (2006) Arterial calcifications seen on mammograms: cardiovascular risk factors, pregnancy, and lactation. Radiology 240 (1):33-38.

TT Keller, D Choi, C Nagel, H Velthuis, VEA Gerdes, NJ Wareham, SA Bingham, R Luben, CE Hack, PH Reitsma, M Levi, KT Khaw, SM Boekholdt. (2006) Tissue factor serum levels and the risk of future coronary artery disease in apparently healthy men and women: the EPIC-Norfolk prospective population study. J Thromb Haemost 4 (11):2391-2396.

TT Keller, SI van Leuven, MC Meuwese, NJ Wareham, R Luben, ES Stroes, EC Hack, M Levi, K Khaw, MS Boekholdt. (2006) Serum levels of mannose-binding lectin and the risk of future coronary artery disease in apparently healthy men and women. Arterioscler Thromb Vasc Biol 26 (10):2345-2350.

M Kataoka, R Warren, R Luben, J Camus, E Denton, E Sala, N Day, K Khaw. (2006) How predictive is breast arterial calcification of cardiovascular disease and risk factors when found at screening mammography? AJR Am J Roentgenol 187 (1):73-80.

K Hoffmann, C Heidemann, C Weikert, MB Schulze, H Boeing. (2006) Estimating the proportion of disease due to classes of sufficient causes. Am J Epidemiol 163 (1):76-83.

KT Khaw. (2006) Epidemiology of coronary heart disease in women. Heart 92 Suppl 3 ():iii2-iii4.

K Khaw, R Jakes, S Bingham, A Welch, R Luben, N Day, N Wareham. (2006) Work and leisure time physical activity assessed using a simple, pragmatic, validated questionnaire and incident cardiovascular disease and all-cause mortality in men and women: The {Europe}an Prospective Investigation into Cancer in Norfolk prospective population study. Int J Epidemiol 35 (4):1034-1043.

MS Boekholdt, TT Keller, NJ Wareham, R Luben, SA Bingham, NE Day, MS Sandhu, WJ Jukema, JJP Kastelein, EC Hack, K Khaw. (2005) Serum levels of type II secretory phospholipase A2 and the risk of future coronary artery disease in apparently healthy men and women: the EPIC-Norfolk Prospective Population Study. Arterioscler Thromb Vasc Biol 25 (4):839-846.

A Trichopoulou, P Orfanos, T Norat, Bueno-de-Mesquita Bas, MC Ocke, PHM Peeters, YT van der Schouw, H Boeing, K Hoffmann, P Boffetta, G Nagel, G Masala, V Krogh, S Panico, R Tumino, P Vineis, C Bamia, A Naska, V Benetou, P Ferrari, N Slimani, G Pera, C Martinez-Garcia, C Navarro, M Rodriguez-Barranco, M Dorronsoro, EA Spencer, TJ Key, S Bingham, K Khaw, E Kesse, F Clavel-Chapelon, M Boutron-Ruault, G Berglund, E Wirfalt, G Hallmans, I Johansson, A Tjonneland, A Olsen, Kim Overvad, HH Hundborg, E Riboli, D Trichopoulos. (2005) Modified Mediterranean diet and survival: EPIC-elderly prospective cohort study. BMJ 330 (7498):991.

PG Surtees, NWJ Wainwright, R Luben, NE Day, K Khaw. (2005) Prospective cohort study of hostility and the risk of cardiovascular disease mortality. Int J Cardiol 100 (1):155-161.

S Sinha, RN Luben, A Welch, S Bingham, NJ Wareham, NE Day, K Khaw. (2005) Fibrinogen and cigarette smoking in men and women in the {Europe}an Prospective Investigation into Cancer in Norfolk (EPIC-Norfolk) population. Eur J Cardiovasc Prev Rehabil 12 (2):144-150.

C Weikert, K Hoffmann, J Dierkes, B Zyriax, K Klipstein-Grobusch, MB Schulze, R Jung, E Windler, H Boeing. (2005) A homocysteine metabolism-related dietary pattern and the risk of coronary heart disease in two independent German study populations. J Nutr 135 (8):1981-1988.

A Trichopoulou, C Bamia, D Trichopoulos. (2005) Mediterranean diet and survival among patients with coronary heart disease in {Greece}. Arch Intern Med 165 (8):929-935.

S Salvatore, N Pellegrini, OV Brenna, D Del Rio, G Frasca, F Brighenti, R Tumino. (2005) Antioxidant characterization of some Sicilian edible wild greens. J Agric Food Chem 53 (24):9465-9471.

E Matteucci, S Passerai, M Mariotti, F Fagnani, I Evangelista, L Rossi, O Giampietro. (2005) Dietary habits and nutritional biomarkers in Italian type 1 diabetes families: evidence of unhealthy diet and combined-vitamin-deficient intakes. Eur J Clin Nutr 59 (1):114-122.

MF Yuyun, K Khaw, R Luben, A Welch, S Bingham, NE Day, NJ Wareham. (2004) Microalbuminuria, cardiovascular risk factors and cardiovascular morbidity in a British population: the EPIC-Norfolk population-based study. Eur J Cardiovasc Prev Rehabil 11 (3):207-213.

MF Yuyun, K Khaw, R Luben, A Welch, S Bingham, NE Day, NJ Wareham. (2004) A prospective study of microalbuminuria and incident coronary heart disease and its prognostic significance in a British population: the EPIC-Norfolk study. Am J Epidemiol 159 (3):284-293.

MF Yuyun, K Khaw, R Luben, A Welch, S Bingham, NE Day, NJ Wareham, Prospective European. (2004) Microalbuminuria independently predicts all-cause and cardiovascular mortality in a British population: The {Europe}an Prospective Investigation into Cancer in Norfolk (EPIC-Norfolk) population study. Int J Epidemiol 33 (1):189-198.

R Villegas, A Salim, MM Collins, A Flynn, IJ Perry. (2004) Dietary patterns in middle-aged Irish men and women defined by cluster analysis. Public Health Nutr 7 (8):1017-1024.

R Villegas, A Salim, A Flynn, IJ Perry. (2004) Prudent diet and the risk of insulin resistance. Nutr Metab Cardiovasc Dis 14 (6):334-343.

vWA Steeg, JA Kuivenhoven, AH Klerkx, SM Boekholdt, GK Hovingh, JJP Kastelein. (2004) Role of CETP inhibitors in the treatment of dyslipidemia. Curr Opin Lipidol 15 (6):631-636.

T Psaltopoulou, A Naska, P Orfanos, D Trichopoulos, T Mountokalakis, A Trichopoulou. (2004) Olive oil, the Mediterranean diet, and arterial blood pressure: the Greek {Europe}an Prospective Investigation into Cancer and Nutrition (EPIC) study. Am J Clin Nutr 80 (4):1012-1018.

T Psaltopoulou, P Orfanos, A Naska, D Lenas, D Trichopoulos, A Trichopoulou. (2004) Prevalence, awareness, treatment and control of hypertension in a general population sample of 26,913 adults in the Greek EPIC study. Int J Epidemiol 33 (6):1345-1352.

K Khaw, N Day, S Bingham, N Wareham. (2004) Observational versus randomised trial evidence. Lancet 364 (9436):753-4; author reply754--5.

K Khaw, N Wareham, S Bingham, R Luben, A Welch, N Day. (2004) Association of hemoglobin A1c with cardiovascular disease and mortality in adults: the {Europe}an prospective investigation into cancer in Norfolk. Ann Intern Med 141 (6):413-420.

NJ Goodson, AJ Silman, DJ Pattison, M Lunt, D Bunn, R Luben, N Day, KT Khaw, DPM Symmons. (2004) Traditional cardiovascular risk factors measured prior to the onset of inflammatory polyarthritis. Rheumatology (Oxford) 43 (6):731-736.

D Canoy, R Luben, A Welch, S Bingham, N Wareham, N Day, KT Khaw. (2004) Abdominal obesity and respiratory function in men and women in the EPIC-Norfolk Study, {United Kingdom}. Am J Epidemiol 159 (12):1140-1149.

MM Bergmann, EJ Jacobs, K Hoffmann, H Boeing. (2004) Agreement of self-reported medical history: comparison of an in-person interview with a self-administered questionnaire. Eur J Epidemiol 19 (5):411-416.

MS Boekholdt, J Kuivenhoven, NJ Wareham, Ron Peters, WJ Jukema, R Luben, SA Bingham, NE Day, JJP Kastelein, K Khaw. (2004) Plasma levels of cholesteryl ester transfer protein and the risk of future coronary artery disease in apparently healthy men and women: the prospective EPIC ({Europe}an Prospective Investigation into Cancer and nutrition)-Norfolk population study. Circulation 110 (11):1418-1423.

MS Boekholdt, Ron Peters, EC Hack, NE Day, R Luben, SA Bingham, NJ Wareham, PH Reitsma, K Khaw. (2004) IL-8 plasma concentrations and the risk of future coronary artery disease in apparently healthy men and women: the EPIC-Norfolk prospective population study. Arterioscler Thromb Vasc Biol 24 (8):1503-1508.

MS Boekholdt, Ron Peters, NE Day, R Luben, SA Bingham, NJ Wareham, EC Hack, PH Reitsma, K Khaw. (2004) Macrophage migration inhibitory factor and the risk of myocardial infarction or death due to coronary artery disease in adults without prior myocardial infarction or stroke: the EPIC-Norfolk Prospective Population study. Am J Med 117 (6):390-397.

PG Surtees, NWJ Wainwright, K Khaw, NE Day. (2003) Functional health status, chronic medical conditions and disorders of mood. Br J Psychiatry 183 ():299-303.

P Surtees, N Wainwright, R Luben, K Khaw, N Day. (2003) Sense of coherence and mortality in men and women in the EPIC-Norfolk {United Kingdom} prospective cohort study. Am J Epidemiol 158 (12):1202-1209.

RW Jakes, NE Day, KT Khaw, R Luben, S Oakes, A Welch, S Bingham, NJ Wareham. (2003) Television viewing and low participation in vigorous recreation are independently associated with obesity and markers of cardiovascular disease risk: EPIC-Norfolk population-based study. Eur J Clin Nutr 57 (9):1089-1096.

TJ Key, PN Appleby, GK Davey, NE Allen, EA Spencer, RC Travis. (2003) Mortality in British vegetarians: review and preliminary results from EPIC-Oxford. Am J Clin Nutr 78 (3 Suppl):533S-538S.

S Ishikura, K Nihei, A Ohtsu, N Boku, S Hironaka, K Mera, M Muto, T Ogino, S Yoshida. (2003) Long-term toxicity after definitive chemoradiotherapy for squamous cell carcinoma of the thoracic esophagus. J Clin Oncol 21 (14):2697-2702.

NWJ Wainwright, PG Surtees. (2002) Time-varying exposure and the impact of stressful life events on onset of affective disorder. Stat Med 21 (14):2077-2091.

S Sieri, A Agudo, E Kesse, K Klipstein-Grobusch, B San-Jose, AA Welch, V Krogh, Group Working. (2002) Alcohol consumption in EPIC cohorts from ten {Europe}an countries. IARC Sci Publ 156 ():173-176.

RW Jakes, NE Day, Bip Patel, K Khaw, S Oakes, R Luben, A Welch, S Bingham, NJ Wareham. (2002) Physical inactivity is associated with lower forced expiratory volume in 1~{s}econd : {Europe}an Prospective Investigation into Cancer-Norfolk Prospective Population Study. Am J Epidemiol 156 (2):139-147.

PK Verkasalo, PN Appleby, NE Allen, G Davey, H Adlercreutz, TJ Key. (2001) Soya intake and plasma concentrations of daidzein and genistein: validity of dietary assessment among eighty British women (Oxford arm of the {Europe}an Prospective Investigation into Cancer and Nutrition). Br J Nutr 86 (3):415-421.

A Trichopoulou, C Gnardellis, A Lagiou, V Benetou, A Naska, D Trichopoulos. (2001) Physical activity and energy intake selectively predict the waist-to-hip ratio in men but not in women. Am J Clin Nutr 74 (5):574-578.

E Kesse, F Clavel-Chapelon, N Slimani, van Liere, EN Group. (2001) Do eating habits differ according to alcohol consumption? Results of a study of the French cohort of the {Europe}an Prospective Investigation into Cancer and Nutrition (E3{N}-EPIC). Am J Clin Nutr 74 (3):322-327.

KT Khaw, S Bingham, A Welch, R Luben, N Wareham, S Oakes, N Day. (2001) Relation between plasma ascorbic acid and mortality in men and women in EPIC-Norfolk prospective study: a prospective population study. {Europe}an Prospective Investigation into Cancer and Nutrition. Lancet 357 (9257):657-663.

KT Khaw, N Wareham, R Luben, S Bingham, S Oakes, A Welch, N Day. (2001) Glycated haemoglobin, diabetes, and mortality in men in Norfolk cohort of european prospective investigation of cancer and nutrition (EPIC-Norfolk). BMJ 322 (7277):15-18.

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