Cambridge University EPIC-Norfolk
   
  EPIC-Norfolk: Publications
(with selected papers relating to the international EPIC study)
 

Notes

For all papers, the button provides a direct link to the relevant journal, where available. The journal website will generally show the abstract.

The button links to a full text version of a paper, if one is available. All of the full text links will work if you have a cam.ac.uk IP address, but some may not work from other institutions. Some of the full text versions are in Adobe Acrobat format.

For books, the button links to the amazon.co.uk entry.

Clicking on the button takes you to our page giving futher details of selected papers.
 

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L Di Benedetto, G Michels, R Luben, K Khaw, R Pfister. (2018) Individual and combined impact of lifestyle factors on atrial fibrillation in apparently healthy men and women: The EPIC-Norfolk prospective population study. Eur J Prev Cardiol ():2047487318782379.

K Khaw, SJ Sharp, L Finikarides, I Afzal, M Lentjes, R Luben, NG Forouhi. (2018) Randomised trial of coconut oil, olive oil or butter on blood lipids and other cardiovascular risk factors in healthy men and women. BMJ Open 8 (3):e020167.

NRV Jones, NG Forouhi, K Khaw, NJ Wareham, P Monsivais. (2018) Accordance to the Dietary Approaches to Stop Hypertension diet pattern and cardiovascular disease in a British, population-based cohort. Eur J Epidemiol 33 (2):235-244.

N Perrot, MS Boekholdt, P Mathieu, NJ Wareham, K Khaw, BJ Arsenault. (2018) Life's simple 7 and calcific aortic valve stenosis incidence in apparently healthy men and women. Int J Cardiol ():.

CG Owen, AR Rudnicka, RA Welikala, MM Fraz, SA Barman, R Luben, SA Hayat, K Khaw, DP Strachan, PH Whincup, PJ Foster. (2018) Retinal vasculometry associations with cardiometabolic risk factors in the {Europe}an Prospective Investigation of Cancer Norfolk study. Ophthalmology ():.

MPY Chan, DC Broadway, AP Khawaja, JLY Yip, DF Garway-Heath, JM Burr, R Luben, S Hayat, N Dalzell, K Khaw, PJ Foster. (2017) Glaucoma and intraocular pressure in EPIC-Norfolk Eye Study: cross sectional study. BMJ 358 ():j3889.

GG Kuhnle, R Luben, K Khaw, M Feelisch. (2017) Sulfate, nitrate and blood pressure - An EPIC interaction between sulfur and nitrogen. Pharmacol Res 122 ():127-129.

N Perrot, R Verbeek, M Sandhu, MS Boekholdt, KG Hovingh, NJ Wareham, K Khaw, BJ Arsenault. (2017) Ideal cardiovascular health influences cardiovascular disease risk associated with high lipoprotein(a) levels and genotype: The EPIC-Norfolk prospective population study. Atherosclerosis 256 ():47-52.

LV Wain, A Vaez, R Jansen, R Joehanes, PJ van der Most, MA Erzurumluoglu, PF OReilly, CP Cabrera, HR Warren, LM Rose, GC Verwoert, J Hottenga, RJ Strawbridge, T Esko, Dan Arking, S Hwang, X Guo, Z Kutalik, S Trompet, N Shrine, A Teumer, JS Ried, JC Bis, AV Smith, N Amin, IM Nolte, L Lyytikainen, A Mahajan, NJ Wareham, E Hofer, PK Joshi, K Kristiansson, M Traglia, Aki Havulinna, A Goel, MA Nalls, S Sober, D Vuckovic, J Luan, F Del Greco, KL Ayers, J Marrugat, D Ruggiero, LM Lopez, T Niiranen, S Enroth, AU Jackson, CP Nelson, JE Huffman, W Zhang, J Marten, I Gandin, SE Harris, T Zemunik, Y Lu, E Evangelou, N Shah, MH de Borst, M Mangino, BP Prins, A Campbell, R Li-Gao, G Chauhan, C Oldmeadow, G Abecasis, M Abedi, CM Barbieri, MR Barnes, C Batini, J Beilby, T Blake, M Boehnke, EP Bottinger, PS Braund, M Brown, M Brumat, H Campbell, JC Chambers, M Cocca, F Collins, J Connell, HJ Cordell, JJ Damman, G Davies, Eco de Geus, R de Mutsert, J Deelen, Y Demirkale, ASF Doney, M Dorr, M Farrall, T Ferreira, M Fraanberg, He Gao, V Giedraitis, C Gieger, F Giulianini, AJ Gow, A Hamsten, TB Harris, A Hofman, EG Holliday, J Hui, M Jarvelin, A Johansson, AD Johnson, P Jousilahti, A Jula, M Kahonen, S Kathiresan, K Khaw, I Kolcic, S Koskinen, C Langenberg, M Larson, LJ Launer, B Lehne, DCM Liewald, Li Lin, L Lind, F Mach, C Mamasoula, C Menni, B Mifsud, Y Milaneschi, A Morgan, AD Morris, AC Morrison, PJ Munson, P Nandakumar, Q Nguyen, T Nutile, AJ Oldehinkel, Ben Oostra, E Org, S Padmanabhan, A Palotie, G Pare, A Pattie, BWJH Penninx, N Poulter, PP Pramstaller, OT Raitakari, M Ren, K Rice, PM Ridker, H Riese, S Ripatti, A Robino, JI Rotter, I Rudan, Y Saba, A Pierre, CF Sala, A Sarin, R Schmidt, R Scott, MA Seelen, DC Shields, D Siscovick, R Sorice, A Stanton, DJ Stott, J Sundstrom, M Swertz, KD Taylor, S Thom, I Tzoulaki, C Tzourio, AG Uitterlinden, Uwe Volker, P Vollenweider, S Wild, G Willemsen, AF Wright, Jie Yao, S Theriault, D Conen, J Attia, P Sever, S Debette, DO Mook-Kanamori, E Zeggini, Tim Spector, Pim van der Harst, CNA Palmer, A Vergnaud, Loos. (2017) Novel Blood Pressure Locus and Gene Discovery Using Genome-Wide Association Study and Expression Data Sets From Blood and the Kidney. Hypertension ():.

JC van Capelleveen, AE Bochem, MS Boekholdt, S Mora, Ron Hoogeveen, CM Ballantyne, PM Ridker, W Sun, PJ Barter, AR Tall, AH Zwinderman, JJP Kastelein, NJ Wareham, K Khaw, KG Hovingh. (2017) Association of High-Density Lipoprotein-Cholesterol Versus Apolipoprotein A-I With Risk of Coronary Heart Disease: The {Europe}an Prospective Investigation Into Cancer-Norfolk Prospective Population Study, the Atherosclerosis Risk in Communities Study, and the Women's Health Study. J Am Heart Assoc 6 (8):.

RM Stoekenbroek, MS Boekholdt, R Luben, KG Hovingh, AH Zwinderman, NJ Wareham, K Khaw, Ron Peters. (2016) Heterogeneous impact of classic atherosclerotic risk factors on different arterial territories: the EPIC-Norfolk prospective population study. Eur Heart J 37 (11):880-889.

W Zhang, F JernerAcopyrightn, BC Lehne, M Chen, RN Luben, C Johnston, A Elshorbagy, RN Eppinga, WR Scott, E Adeyeye, J Scott, RH BAPger, K Khaw, Pim van der Harst, NJ Wareham, RS Vasan, JC Chambers, H Refsum, JS Kooner. (2016) Genome-wide association reveals that common genetic variation in the kallikrein-kinin system is associated with serum L-arginine levels. Thrombosis and haemostasis 116 ():1041-1049.

S Chuang, H Boeing, S Vollset, O Midttun, P Ueland, B Bueno-de-Mesquita, M Lajous, Guy Fagherazzi, M Boutron-Ruault, R Kaaks, T Kuehn, T Pischon, D Drogan, A Tjonneland, Kim Overvad, RJ Quiros, A Agudo, E Molina-Montes, M Dorronsoro, J Huerta, A Barricarte, K Khaw, NJ Wareham, RC Travis, A Trichopoulou, P Lagiou, D Trichopoulos, G Masala, C Agnoli, R Tumino, A Mattiello, PH Peeters, E Weiderpass, R Palmqvist, I Ljuslinder, M Gunter, Y Lu, AJ Cross, E Riboli, P Vineis, K Aleksandrova. (2016) Cellular immune activity biomarker neopterin is associated hyperlipidemia: results from a large population-based study. Immun Ageing 13 ():5.

L Chaker, C Baumgartner, WPJ den Elzen, T Collet, AM Ikram, MR Blum, A Dehghan, C Drechsler, RN Luben, MLP Portegies, G Iervasi, M Medici, DJ Stott, RP Dullaart, Ian Ford, A Bremner, AB Newman, C Wanner, JA Sgarbi, M DAPrr, WT Longstreth, BM Psaty, L Ferrucci, Rui Maciel, RG Westendorp, WJ Jukema, G Ceresini, M Imaizumi, A Hofman, SJL Bakker, JA Franklyn, K Khaw, DC Bauer, JP Walsh, S Razvi, J Gussekloo, H VAPlzke, OH Franco, AR Cappola, N Rodondi, RP Peeters, T Collaboration. (2016) Thyroid Function Within the Reference Range and the Risk of Stroke: An Individual Participant Data Analysis. The Journal of clinical endocrinology and metabolism 101 ():4270-4282.

AP Khawaja, H Springelkamp, C Creuzot-Garcher, C Delcourt, A Hofman, R HAPhn, AI Iglesias, RCW Wolfs, J Korobelnik, R Silva, F Topouzis, KM Williams, AM Bron, GHS Buitendijk, M Cachulo, A Cougnard-GrAcopyrightgoire, J Dartigues, CJ Hammond, N Pfeiffer, A Salonikiou, CM van Duijn, JR Vingerling, RN Luben, A Mirshahi, J Lamparter, CCW Klaver, NM Jansonius, PJ Foster, Eye European. (2016) Associations with intraocular pressure across {Europe}: The {Europe}an Eye Epidemiology (E(3)) Consortium. European journal of epidemiology ():.

DC Muller, N Murphy, M Johansson, P Ferrari, KK Tsilidis, M Boutron-Ruault, F Clavel, L Dartois, K Li, R Kaaks, C Weikert, M Bergmann, H Boeing, A TjAcnneland, Kim Overvad, LM Redondo, A Agudo, E Molina-Portillo, JM Altzibar, L Cirera, Eva Ardanaz, K Khaw, NJ Wareham, TJ Key, RC Travis, C Bamia, P Orfanos, A Trichopoulou, D Palli, V Pala, R Tumino, P Vineis, S Panico, B Bueno-de-Mesquita, MWM Verschuren, EA Struijk, PH Peeters, G EngstrAPm, O Melander, M Sund, E Weiderpass, G Skeie, E Lund, T Norat, M Gunter, E Riboli, P Brennan. (2016) Modifiable causes of premature death in middle-age in Western {Europe}: results from the EPIC cohort study. BMC medicine 14 ():87.

R Pfister, J Bragelmann, G Michels, NJ Wareham, R Luben, K Khaw. (2015) Performance of the CHARGE-AF risk model for incident atrial fibrillation in the EPIC Norfolk cohort. Eur J Prev Cardiol 22 (7):932-939.

R Scragg, D Waayer, AW Stewart, CMM Lawes, Les Toop, J Murphy, K Khaw, Jr Camargo. (2015) The Vitamin DAssessment (ViDA) Study: design of a randomized controlled trial of vitamin D supplementation for the prevention of cardiovascular disease, acute respiratory infection, falls and non-vertebral fractures. J Steroid Biochem Mol Biol ():.

D Saleheen, R Scott, S Javad, Wei Zhao, A Rodrigues, A Picataggi, D Lukmanova, ML Mucksavage, R Luben, J Billheimer, JJP Kastelein, MS Boekholdt, K Khaw, N Wareham, DJ Rader. (2015) Association of {HDL} cholesterol efflux capacity with incident coronary heart disease events: a prospective case-control study. Lancet Diabetes Endocrinol 3 (7):507-513.

A Vogiatzoglou, AA Mulligan, A Bhaniani, MAH Lentjes, A McTaggart, RN Luben, C Heiss, M Kelm, MW Merx, JPE Spencer, H Schroeter, K Khaw, GGC Kuhnle. (2015) Associations between flavan-3-ol intake and CVD risk in the Norfolk cohort of the {Europe}an Prospective Investigation into Cancer (EPIC-Norfolk). Free Radic Biol Med ():.

JLY Yip, AP Khawaja, MPY Chan, DC Broadway, T Peto, A Tufail, R Luben, S Hayat, A Bhaniani, NJ Wareham, K Khaw, PJ Foster. (2015) Cross Sectional and Longitudinal Associations between Cardiovascular Risk Factors and Age Related Macular Degeneration in the EPIC-Norfolk Eye Study. PLoS One 10 (7):e0132565.

SD Ostergaard, S Mukherjee, SJ Sharp, P Proitsi, LA Lotta, F Day, JRB Perry, KL Boehme, S Walter, JS Kauwe, LE Gibbons, Disease Alzheimer{\textquoteright}s, D Consortium, Consortium C-InterAct, EB Larson, JF Powell, C Langenberg, PK Crane, NJ Wareham, RA Scott. (2015) Associations between Potentially Modifiable Risk Factors and Alzheimer Disease: A Mendelian Randomization Study. PLoS Med 12 (6):e1001841; discussion e1001841.

LKM Bain, PK Myint, Amy Jennings, MAH Lentjes, RN Luben, K Khaw, NJ Wareham, AA Welch. (2015) The relationship between dietary magnesium intake, stroke and its major risk factors, blood pressure and cholesterol, in the EPIC-Norfolk cohort. Int J Cardiol 196 ():108-114.

S Lachman, Ron Peters, M Lentjes, AA Mulligan, RN Luben, NJ Wareham, K Khaw, MS Boekholdt. (2015) Ideal cardiovascular health and risk of cardiovascular events in the EPIC-Norfolk prospective population study. Eur J Prev Cardiol ():.

P Monsivais, P Scarborough, T Lloyd, A Mizdrak, R Luben, AA Mulligan, NJ Wareham, J Woodcock. (2015) Greater accordance with the Dietary Approaches to Stop Hypertension dietary pattern is associated with lower diet-related greenhouse gas production but higher dietary costs in the {United Kingdom}. Am J Clin Nutr 102 (1):138-145.

PK Myint, KR Hawkins, AB Clark, RN Luben, NJ Wareham, KT Khaw, AM Wilson. (2015) Long-term mortality of hospitalized pneumonia in the EPIC-Norfolk cohort. Epidemiol Infect ():1-7.

Yue Leng, S Ahmadi-Abhari, NWJ Wainwright, FP Cappuccio, PG Surtees, R Luben, C Brayne, K Khaw. (2014) Daytime napping, sleep duration and serum C reactive protein: a population-based cohort study. BMJ Open 4 (11):e006071.

C Rheaume, BJ Arsenault, J Despres, Faha, MS Boekholdt, NJ Wareham, K Khaw, Mbb Chir. (2014) Impact of abdominal obesity and systemic hypertension on risk of coronary heart disease in men and women: the EPIC-Norfolk Population Study. J Hypertens 32 (11):2224-30; discussion 2230.

R Pfister, G Michels, J Bragelmann, SJ Sharp, R Luben, NJ Wareham, K Khaw. (2014) Plasma vitamin C and risk of hospitalisation with diagnosis of atrial fibrillation in men and women in EPIC-Norfolk prospective study. Int J Cardiol 177 (3):830-835.

R Pfister, G Michels, SJ Sharp, R Luben, NJ Wareham, K Khaw. (2014) Estimated urinary sodium excretion and risk of heart failure in men and women in the EPIC-Norfolk study. Eur J Heart Fail ():.

R Pfister, G Michels, SJ Sharp, R Luben, NJ Wareham, K Khaw. (2014) Low bone mineral density predicts incident heart failure in men and women: the EPIC ({Europe}an Prospective Investigation into Cancer and Nutrition)-Norfolk prospective study. JACC Heart Fail 2 (4):380-389.

J Simino, G Shi, JC Bis, DI Chasman, GB Ehret, X Gu, X Guo, S Hwang, E Sijbrands, AV Smith, GC Verwoert, JL Bragg-Gresham, G Cadby, P Chen, C Cheng, T Corre, RA de Boer, A Goel, T Johnson, C Khor, L, Study, C Lluis-Ganella, J Luan, L Lyytikainen, IM Nolte, X Sim, S Sober, PJ van der Most, N Verweij, J Zhao, N Amin, E Boerwinkle, C Bouchard, A Dehghan, G Eiriksdottir, R Elosua, OH Franco, C Gieger, TB Harris, S Hercberg, A Hofman, AL James, AD Johnson, M Kahonen, K Khaw, Z Kutalik, MG Larson, LJ Launer, Guo Li, J Liu, K Liu, AC Morrison, G Navis, R Ong, GJ Papanicolau, BW Penninx, BM Psaty, LJ Raffel, OT Raitakari, K Rice, F Rivadeneira, LM Rose, S Sanna, RA Scott, DS Siscovick, RP Stolk, AG Uitterlinden, D Vaidya, MM van der Klauw, RS Vasan, E Vithana, Uwe Volker, H Volzke, H Watkins, TL Young, Tin Aung, M Bochud, M Farrall, CA Hartman, M Laan, EG Lakatta, T Lehtimaki, RJF Loos, G Lucas, P Meneton, LJ Palmer, R Rettig, H Snieder, SE Tai, Y Teo, Pim van der Harst, NJ Wareham, C Wijmenga, T Wong, M Fornage, V Gudnason, D Levy, W Palmas, PM Ridker, JI Rotter, CM van Duijn, JCM Witteman, A Chakravarti, DC Rao. (2014) Gene-Age Interactions in Blood Pressure Regulation: A Large-Scale Investigation with the CHARGE, Global {BP}gen, and {IC}BP Consortia. Am J Hum Genet 95 (1):24-38.

CaffeineConsortium, , Cornelis, , Byrne, , Esko, , Nalls, , Ganna, , Paynter, , Monda, , Amin, , Fischer, , Renstrom, , Ngwa, , Huikari, , Cavadino, , Nolte, , Teumer, , Yu, , Marques-Vidal, , Rawal, , Manichaikul, , Wojczynski, , Vink, , Zhao, , Burlutsky, , Lahti, , Mikkil"a, , Lemaitre, , Eriksson, , Musani, , Tanaka, , Geller, , Luan, , Hui, , M"agi, , Dimitriou, , Garcia, , Ho, , Wright, , Rose, , Magnusson, , Pedersen, , Couper, , Oostra, , Hofman, , Ikram, , Tiemeier, , Uitterlinden, FJA van-Rooij, , Barroso, , Johansson, , Xue, , Kaakinen, , Milani, , Power, , Snieder, , Stolk, , Baumeister, , Biffar, , Gu, , Bastardot, , Kutalik, , Jacobs, , Forouhi, , Mihailov, , Lind, , Lindgren, , Micha"elsson, , Morris, , Jensen, , Khaw, , Luben, , Wang, , M"annist"o, , Per"al"a, , K"ah"onen, , Lehtim"aki, , Viikari, , Mozaffarian, , Mukamal, , Psaty, , D"oring, , Heath, , Montgomery, , Dahmen, , Carithers, , Tucker, , Ferrucci, , Boyd, , Melbye, , Treur, , Mellstr"om, , Hottenga, , Prokopenko, , T"onjes, , Deloukas, , Kanoni, , Lorentzon, , Houston, , Liu, , Danesh, , Rasheed, , Mason, , Zonderman, , Franke, , Kristal, PDG , ABE , UKKBE , , Karjalainen, , Reed, , Westra, , Evans, , Saleheen, , Harris, , Dedoussis, , Curhan, , Stumvoll, , Beilby, , Pasquale, , Feenstra, , Bandinelli, , Ordovas, , Chan, , Peters, , Ohlsson, , Gieger, , Martin, , Waldenberger, , Siscovick, , Raitakari, , Eriksson, , Mitchell, , Hunter, , Kraft, , Rimm, , Boomsma, , Borecki, , Loos, , Wareham, , Vollenweider, , Caporaso, , Grabe, , Neuhouser, , Wolffenbuttel, , Hu, , Hypp"onen, , J"arvelin, , Cupples, , Franks, , Ridker, CM van-Duijn, , Heiss, , Metspalu, , North, , Ingelsson, , Nettleton, RM van-Dam, , Chasman. (2014) Genome-wide meta-analysis identifies six novel loci associated with habitual coffee consumption. Mol Psychiatry ():.

I Consortium. (2014) Adherence to predefined dietary patterns and incident type 2 diabetes in {Europe}an populations: EPIC-InterAct Study. Diabetologia 57 (2):321-333.

SK Ganesh, DI Chasman, MG Larson, X Guo, G Verwoert, JC Bis, X Gu, AV Smith, M Yang, Yan Zhang, G Ehret, LM Rose, S Hwang, GJ Papanicolau, EJ Sijbrands, K Rice, G Eiriksdottir, V Pihur, PM Ridker, RS Vasan, C Newton-Cheh, Blood Global, LJ Raffel, N Amin, JI Rotter, K Liu, LJ Launer, M Xu, M Caulfield, AC Morrison, AD Johnson, D Vaidya, A Dehghan, Guo Li, C Bouchard, TB Harris, He Zhang, E Boerwinkle, DS Siscovick, Wei Gao, AG Uitterlinden, F Rivadeneira, A Hofman, CJ Willer, OH Franco, Y Huo, JCM Witteman, PB Munroe, V Gudnason, W Palmas, C van Duijn, M Fornage, D Levy, BM Psaty, A Chakravarti. (2014) Effects of long-term averaging of quantitative blood pressure traits on the detection of genetic associations. Am J Hum Genet 95 (1):49-65.

MV Holmes, CE Dale, L Zuccolo, RJ Silverwood, Y Guo, Z Ye, D Prieto-Merino, A Dehghan, S Trompet, A Wong, A Cavadino, D Drogan, S Padmanabhan, S Li, A Yesupriya, M Leusink, J Sundstrom, JA Hubacek, H Pikhart, DI Swerdlow, AG Panayiotou, SA Borinskaya, C Finan, S Shah, KB Kuchenbaecker, T Shah, J Engmann, L Folkersen, Per Eriksson, F Ricceri, O Melander, C Sacerdote, DM Gamble, S Rayaprolu, OA Ross, S McLachlan, O Vikhireva, I Sluijs, RA Scott, V Adamkova, L Flicker, FM van Bockxmeer, C Power, P Marques-Vidal, Tom Meade, MG Marmot, JM Ferro, S Paulos-Pinheiro, SE Humphries, PJ Talmud, I Leach, N Verweij, A Linneberg, Tea Skaaby, PA Doevendans, MJ Cramer, Pim van der Harst, OH Klungel, NF Dowling, AF Dominiczak, M Kumari, AN Nicolaides, C Weikert, H Boeing, S Ebrahim, Tom Gaunt, JF Price, L Lannfelt, A Peasey, R Kubinova, A Pajak, S Malyutina, MI Voevoda, A Tamosiunas, A {Maitland-van der Zee}, PE Norman, GJ Hankey, MM Bergmann, A Hofman, OH Franco, J Cooper, J Palmen, W Spiering, Pim Jong, D Kuh, R Hardy, AG Uitterlinden, AM Ikram, Ian Ford, E Hypponen, OP Almeida, NJ Wareham, K Khaw, A Hamsten, LN Husemoen, A Tjonneland, JS Tolstrup, E Rimm, JWJ Beulens, MWM Verschuren, CN Onland-Moret, MH Hofker, GS Wannamethee, PH Whincup, R Morris, AM Vicente, H Watkins, M Farrall, WJ Jukema, J Meschia, AL Cupples, SJ Sharp, M Fornage, C Kooperberg, AZ LaCroix, JY Dai, MB Lanktree, DS Siscovick, E Jorgenson, B Spring, J Coresh, Yun Li, SG Buxbaum, PJ Schreiner, CR Ellison, MY Tsai, SR Patel, S Redline, AD Johnson, Ron Hoogeveen, H Hakonarson, JI Rotter, E Boerwinkle, PIW Bakker, M Kivimaki, FW Asselbergs, N Sattar, DA Lawlor, J Whittaker, G Smith, K Mukamal, BM Psaty, JG Wilson, LA Lange, A Hamidovic, AD Hingorani, BG Nordestgaard, M Bobak, DA Leon, C Langenberg, Tom Palmer, AP Reiner, BJ Keating, F Dudbridge, JP Casas, I, Consortium. (2014) Association between alcohol and cardiovascular disease: Mendelian randomisation analysis based on individual participant data. BMJ 349 ():g4164.

AC Day, AP Khawaja, T Peto, S Hayat, R Luben, DC Broadway, K Khaw, PJ Foster. (2013) The small eye phenotype in the EPIC-Norfolk eye study: prevalence and visual impairment in microphthalmos and nanophthalmos. BMJ Open 3 (7):.

AC Day, DF Garway-Heath, DC Broadway, Y Jiang, S Hayat, N Dalzell, K Khaw, PJ Foster. (2013) Spectral domain optical coherence tomography imaging of the aqueous outflow structures in normal participants of the EPIC-Norfolk Eye Study. Br J Ophthalmol 97 (2):189-195.

ME Emans, CAJM Gaillard, R Pfister, MW Tanck, MS Boekholdt, NJ Wareham, K Khaw. (2013) Red cell distribution width is associated with physical inactivity and heart failure, independent of established risk factors, inflammation or iron metabolism; the EPIC-Norfolk study. Int J Cardiol ():.

D GLGC, U Bioinformatics, CJ Willer, EM Schmidt, S Sengupta, GM Peloso, S Gustafsson, S Kanoni, A Ganna, Jin Chen, ML Buchkovich, S Mora, JS Beckmann, JL Bragg-Gresham, H Chang, Aye Demirkan, HM Den Hertog, Ron Do, LA Donnelly, GB Ehret, T Esko, MF Feitosa, T Ferreira, K Fischer, P Fontanillas, RM Fraser, DF Freitag, D Gurdasani, K Heikkila, E Hypponen, A Isaacs, AU Jackson, Asa Johansson, T Johnson, M Kaakinen, J Kettunen, ME Kleber, X Li, J Luan, L Lyytikainen, PKE Magnusson, M Mangino, E Mihailov, May Montasser, M Muller-Nurasyid, IM Nolte, JR OConnell, CD Palmer, M Perola, A Petersen, S Sanna, R Saxena, SK Service, S Shah, D Shungin, C Sidore, Ci Song, RJ Strawbridge, Ida Surakka, T Tanaka, TM Teslovich, G Thorleifsson, EG Van den Herik, BF Voight, KA Volcik, LL Waite, A Wong, Y Wu, W Zhang, D Absher, G Asiki, I Barroso, LF Been, JL Bolton, LL Bonnycastle, P Brambilla, MS Burnett, G Cesana, M Dimitriou, ASF Doney, A Doring, P Elliott, SE Epstein, G Eyjolfsson, B Gigante, MO Goodarzi, H Grallert, ML Gravito, CJ Groves, G Hallmans, A Hartikainen, C Hayward, D Hernandez, AA Hicks, H Holm, Y Hung, T Illig, MR Jones, P Kaleebu, JJP Kastelein, K Khaw, E Kim, N Klopp, P Komulainen, M Kumari, C Langenberg, T Lehtimaki, S Lin, J Lindstrom, RJF Loos, F Mach, WL McArdle, C Meisinger, BD Mitchell, G Muller, R Nagaraja, N Narisu, TVM Nieminen, RN Nsubuga, I Olafsson, Ken Ong, A Palotie, T Papamarkou, C Pomilla, A Pouta, DJ Rader, MP Reilly, PM Ridker, F Rivadeneira, I Rudan, A Ruokonen, N Samani, H Scharnagl, J Seeley, K Silander, A Stancakova, K Stirrups, Amy Swift, L Tiret, AG Uitterlinden, JL van Pelt, S Vedantam, N Wainwright, C Wijmenga, SH Wild, G Willemsen, Tom Wilsgaard, JF Wilson, EH Young, J Zhao, LS Adair, D Arveiler, TL Assimes, S Bandinelli, F Bennett, M Bochud, BO Boehm, DI Boomsma, IB Borecki, SR Bornstein, P Bovet, M Burnier, H Campbell, A Chakravarti, JC Chambers, Y Chen, Fr Collins. (2013) Discovery and refinement of loci associated with lipid levels. Nat Genet 45 (11):1274-1283.

AP Khawaja, MPY Chan, DC Broadway, DF Garway-Heath, R Luben, JLY Yip, S Hayat, K Khaw, PJ Foster. (2013) Laser scanning tomography in the EPIC-Norfolk Eye Study: principal components and associations. Invest Ophthalmol Vis Sci 54 (10):6638-6645.

AP Khawaja, MPY Chan, DF Garway-Heath, DC Broadway, R Luben, JC Sherwin, S Hayat, K Khaw, PJ Foster. (2013) Associations with retinal nerve fiber layer measures in the EPIC-Norfolk Eye Study. Invest Ophthalmol Vis Sci 54 (7):5028-5034.

R Pfister, RN Luben, K Khaw, NJ Wareham. (2013) Common genetic variants of the natriuretic peptide gene locus are not associated with heart failure risk in participants in the EPIC-Norfolk study. Eur J Heart Fail 15 (6):624-627.

X Sim, RA Jensen, KM Ikram, M Cotch, X Li, S MacGregor, J Xie, A Smith, E Boerwinkle, P Mitchell, R Klein, BEK Klein, NL Glazer, T Lumley, B McKnight, BM Psaty, PTVM de Jong, A Hofman, F Rivadeneira, AG Uitterlinden, CM van Duijn, T Aspelund, G Eiriksdottir, TB Harris, F Jonasson, LJ Launer, Trust Wellcome, J Attia, PN Baird, S Harrap, EG Holliday, M Inouye, E Rochtchina, RJ Scott, A Viswanathan, G,BP Consortium, Guo Li, NL Smith, KL Wiggins, JZ Kuo, KD Taylor, AW Hewitt, NG Martin, GW Montgomery, C Sun, TL Young, DA Mackey, NR van Zuydam, ASF Doney, CNA Palmer, AD Morris, JI Rotter, SE Tai, V Gudnason, JR Vingerling, DS Siscovick, J Wang, TY Wong. (2013) Genetic loci for retinal arteriolar microcirculation. PLoS One 8 (6):e65804.

GM Singh, G Danaei, F Farzadfar, GA Stevens, M Woodward, D Wormser, S Kaptoge, G Whitlock, Q Qiao, S Lewington, E Di Angelantonio, S Hoorn, CMM Lawes, MK Ali, D Mozaffarian, M Ezzati, Burden Global, Epidemiology: Diabetes, Risk Emerging, Studies Prospective. (2013) The age-specific quantitative effects of metabolic risk factors on cardiovascular diseases and diabetes: a pooled analysis. PLoS One 8 (7):e65174.

P Wennberg, O Rolandsson, D {van der A}, AMW Spijkerman, R Kaaks, H Boeing, S Feller, MM Bergmann, C Langenberg, SJ Sharp, N Forouhi, E Riboli, N Wareham. (2013) Self-rated health and type 2 diabetes risk in the {Europe}an Prospective Investigation into Cancer and Nutrition-InterAct study: a case-cohort study. BMJ Open 3 (3):.

N Wainwright, S Levy, J Pico, RN Luben, PG Surtees, K Khaw. (2013) Social Adversity Experience and Blood Pressure Control Following Antihypertensive Medication Use in a Community Sample of Older Adults. Int J Behav Med ():.

PG Surtees, NWJ Wainwright, KA Pooley, RN Luben, K Khaw, DF Easton, AM Dunning. (2012) Educational attainment and mean leukocyte telomere length in women in the {Europe}an Prospective Investigation into Cancer (EPIC)-Norfolk population study. Brain Behav Immun 26 (3):414-418.

R Pfister, G Michels, SJ Sharp, R Luben, NJ Wareham, K Khaw. (2012) Resting heart rate and incident heart failure in apparently healthy men and women in the EPIC-Norfolk study. Eur J Heart Fail 14 (10):1163-1170.

D Melzer, NJ Osborne, WE Henley, R Cipelli, A Young, C Money, P McCormack, R Luben, K Khaw, NJ Wareham, TS Galloway. (2012) Urinary bisphenol A concentration and risk of future coronary artery disease in apparently healthy men and women. Circulation 125 (12):1482-1490.

K Ray, NWJ Wainwright, L Visser, J Witteman, M Breteler, B Ambegaonkar, A Hofman, B Stricker, N Wareham, K Khaw, M Sandhu. (2012) Changes in {HDL} cholesterol and cardiovascular outcomes after lipid modification therapy. Heart 98 (10):780-785.

ERFC, R Sreenivasa, K Stephen, T Alexander, A Emanuele, Gao Pei, S Nadeem, WH Peter, MJ Kenneth, GF Richard, H Ingar, N Inger, F Astrid, N Peter, L Sarah, C Rory, G Vilmundur, TG Simon, S Naveed, S Elizabeth, B Frank, D John. (2011) Diabetes mellitus, fasting glucose, and risk of cause-specific death. N Engl J Med 364 (9):829-841.

ICBP-GWAS, , Ehret, , Munroe, , Rice, , Bochud, , Johnson, , Chasman, , Smith, , Tobin, , Verwoert, , Hwang, , Pihur, , Vollenweider, , OReilly, , Amin, , Bragg-Gresham, , Teumer, , Glazer, , Launer, , Zhao, , Aulchenko, , Heath, , S\~ober, , Parsa, , Luan, , Arora, , Dehghan, , Zhang, , Lucas, , Hicks, , Jackson, , Peden, , Tanaka, , Wild, , Rudan, , Igl, , Milaneschi, , Parker, , Fava, , Chambers, , Fox, , Kumari, , Go, P Harst, , Kao, , Sj"ogren, , Vinay, , Alexander, , Tabara, , Shaw-Hawkins, , Whincup, , Liu, , Shi, , Kuusisto, , Tayo, , Seielstad, , Sim, , Nguyen, , Lehtim"aki, , Matullo, , Wu, , Gaunt, , Onland-Moret, , Cooper, , Platou, , Org, , Hardy, , Dahgam, , Palmen, , Vitart, , Braund, , Kuznetsova, , Uiterwaal, , Adeyemo, , Palmas, , Campbell, , Ludwig, , Tomaszewski, , Tzoulaki, , Palmer, CARDRAM , CKD , , , CHARGEHF , , Aspelund, , Garcia, , Chang, , OConnell, , Steinle, , Grobbee, , Arking, , Kardia, , Morrison, , Hernandez, , Najjar, , McArdle, , Hadley, , Brown, , Connell, , Hingorani, , Day, , Lawlor, , Beilby, , Lawrence, , Clarke, , Hopewell, , Ongen, , Dreisbach, , Li, , Young, , Bis, , K"ah"onen, , Viikari, , Adair, , Lee, , Chen, , Olden, , Pattaro, , Bolton, , K"ottgen, , Bergmann, , Mooser, , Chaturvedi, , Frayling, , Islam, , Jafar, , Erdmann, , Kulkarni, , Bornstein, , Gr"assler, , Groop, , Voight, , Kettunen, , Howard, , Taylor, , Guarrera, , Ricceri, , Emilsson, , Plump, , Barroso, , Khaw, , Weder, , Hunt, , Sun, , Bergman, , Collins, , Bonnycastle, , Scott, , Stringham, , Peltonen, , Perola, , Vartiainen, , Brand, , Staessen, , Wang, , Burton, , Artigas, , Dong, , Snieder, , Wang, , Zhu, , Lohman, , Rudock, , Heckbert, , Smith, , Wiggins, , Doumatey, , Shriner, , Veldre, , Viigimaa, , Kinra, , Prabhakaran, , Tripathy, , Langefeld, , Rosengren, , Thelle, , Corsi, , Singleton, , Forrester, , Hilton, , McKenzie, , Salako, , Iwai, , Kita, , Ogihara, , Ohkubo, , Okamura. (2011) Genetic variants in novel pathways influence blood pressure and cardiovascular disease risk. Nature 478 (7367):103-109.

P Chamnan, RK Simmons, R Jackson, KT Khaw, NJ Wareham, SJ Griffin. (2011) Non-diabetic hyperglycaemia and cardiovascular risk: moving beyond categorisation to individual interpretation of absolute risk. Diabetologia 54 (2):291-299.

Risk Emerging, D Wormser, S Kaptoge, E Angelantonio, AM Wood, L Pennells, A Thompson, N Sarwar, JR Kizer, DA Lawlor, BG Nordestgaard, P Ridker, V Salomaa, J Stevens, M Woodward, N Sattar, R Collins, SG Thompson, G Whitlock, J Danesh. (2011) Separate and combined associations of body-mass index and abdominal adiposity with cardiovascular disease: collaborative analysis of 58 prospective studies. Lancet 377 (9771):1085-1095.

PJ Foster, DC Broadway, DF Garway-Heath, J Yip, R Luben, S Hayat, N Dalzell, NJ Wareham, K Khaw. (2011) Intraocular Pressure and Corneal Biomechanics in an Adult British Population - The EPIC-Norfolk Eye Study. Invest Ophthalmol Vis Sci ():.

K Wijndaele, S Brage, H Besson, K Khaw, SJ Sharp, R Luben, A Bhaniani, NJ Wareham, Ulf Ekelund. (2011) Television Viewing and Incident Cardiovascular Disease: Prospective Associations and Mediation Analysis in the EPIC Norfolk Study. PLoS One 6 (5):e20058.

JLY Yip, D Broadway, R Luben, DF Garway-Heath, S Hayat, N Dalzell, P Lee, A Bhaniani, N Wareham, K Khaw, PJ Foster. (2011) Physical Activity and Ocular Perfusion Pressure- The EPIC Norfolk Eye Study. Invest Ophthalmol Vis Sci ():.

R Pfister, S Sharp, R Luben, P Welsh, I Barroso, V Salomaa, A Meirhaeghe, K Khaw, N Sattar, C Langenberg, NJ Wareham. (2011) Mendelian randomization study of B-type natriuretic peptide and type 2 diabetes: evidence of causal association from population studies. PLoS Med 8 (10):e1001112.

R Pfister, SJ Sharp, R Luben, NJ Wareham, K Khaw. (2011) Plasma vitamin C predicts incident heart failure in men and women in {Europe}an Prospective Investigation into Cancer and Nutrition-Norfolk prospective study. Am Heart J 162 (2):246-253.

PK Myint, RN Luben, NJ Wareham, K Khaw. (2011) Association between plasma vitamin C concentrations and blood pressure in the {Europe}an prospective investigation into cancer-norfolk population-based study. Hypertension 58 (3):372-379.

JS Rana, BJ Arsenault, J Despres, M Cote, PJ Talmud, Ewa Ninio, WJ Jukema, NJ Wareham, JJP Kastelein, K Khaw, MS Boekholdt. (2011) Inflammatory biomarkers, physical activity, waist circumference, and risk of future coronary heart disease in healthy men and women. Eur Heart J 32 (3):336-344.

A Ravandi, MS Boekholdt, Z Mallat, PJ Talmud, JJP Kastelein, NJ Wareham, ER Miller, J Benessiano, A Tedgui, JL Witztum, K Khaw, S Tsimikas. (2011) Relationship of IgG and IgM autoantibodies and immune complexes to oxidized LDL with markers of oxidation and inflammation and cardiovascular events: results from the EPIC-Norfolk Study. J Lipid Res 52 (10):1829-1836.

T Johnson, Tom Gaunt, SJ Newhouse, S Padmanabhan, M Tomaszewski, M Kumari, RW Morris, I Tzoulaki, ET OBrien, NR Poulter, P Sever, DC Shields, S Thom, SG Wannamethee, PH Whincup, MJ Brown, JM Connell, RJ Dobson, PJ Howard, CA Mein, A Onipinla, Sue Shaw-Hawkins, Yun Zhang, G Smith, Ian Day, DA Lawlor, AH Goodall, C, Consortium, GF Fowkes, GR Abecasis, P Elliott, V Gateva, G,B Consortium, PS Braund, PR Burton, CP Nelson, MD Tobin, Pim van der Harst, N Glorioso, H Neuvrith, E Salvi, Jan Staessen, A Stucchi, N Devos, X Jeunemaitre, P Plouin, J Tichet, P Juhanson, E Org, M Putku, S Sober, G Veldre, M Viigimaa, A Levinsson, A Rosengren, Dag Thelle, CE Hastie, T Hedner, Wai Lee, O Melander, B Wahlstrand, R Hardy, A Wong, JA Cooper, J Palmen, Li Chen, AFR Stewart, GA Wells, H Westra, MGM Wolfs, R Clarke, M Franzosi, A Goel, A Hamsten, M Lathrop, JF Peden, Udo Seedorf, H Watkins, WH Ouwehand, J Sambrook, J Stephens, J Casas, F Drenos, MV Holmes, M Kivimaki, S Shah, T Shah, PJ Talmud, J Whittaker, C Wallace, C Delles, M Laan, D Kuh, SE Humphries, F Nyberg, D Cusi, R Roberts, C Newton-Cheh, L Franke, AV Stanton, AF Dominiczak, M Farrall, AD Hingorani, NJ Samani, MJ Caulfield, PB Munroe. (2011) Blood pressure loci identified with a gene-centric array. Am J Hum Genet 89 (6):688-700.

Risk Emerging, S Kaptoge, E Angelantonio, G Lowe, MB Pepys, SG Thompson, R Collins, J Danesh. (2010) C-reactive protein concentration and risk of coronary heart disease, stroke, and mortality: an individual participant meta-analysis. Lancet 375 (9709):132-140.

RN Freitas, K Khaw, Wu Kelvin, R Bowman, H Jeffery, R Luben, NJ Wareham, S Rodwell. (2010) HMGCR gene polymorphism is associated with stroke risk in the EPIC-Norfolk study. Eur J Cardiovasc Prev Rehabil 17 (1):89-93.

MS Boekholdt, SM Titan, WM Wiersinga, K Chatterjee, DCG Basart, R Luben, NJ Wareham, K Khaw. (2010) Initial thyroid status and cardiovascular risk factors: the EPIC-Norfolk prospective population study. Clin Endocrinol (Oxf) 72 (3):404-410.

BJ Arsenault, I Lemieux, J Despres, NJ Wareham, JJP Kastelein, K Khaw, MS Boekholdt. (2010) The hypertriglyceridemic-waist phenotype and the risk of coronary artery disease: results from the EPIC-Norfolk prospective population study. CMAJ 182 (13):1427-1432.

S Tsimikas, Z Mallat, PJ Talmud, JJP Kastelein, NJ Wareham, MS Sandhu, ER Miller, J Benessiano, A Tedgui, JL Witztum, K Khaw, MS Boekholdt. (2010) Oxidation-specific biomarkers, lipoprotein(a), and risk of fatal and nonfatal coronary events. J Am Coll Cardiol 56 (12):946-955.

H Ward, RN Luben, NJ Wareham, K Khaw. (2010) CHD risk in relation to alcohol intake from categorical and open-ended dietary instruments. Public Health Nutr ():1-8.

PK Myint, RN Luben, PG Surtees, NWJ Wainwright, NJ Wareham, K Khaw. (2010) Physical functional health predicts the incidence of coronary heart disease in the {Europe}an Prospective Investigation into Cancer-Norfolk prospective population-based study. Int J Epidemiol 39 (4):996-1003.

PK Myint, RD Smith, RN Luben, PG Surtees, NWJ Wainwright, NJ Wareham, SA Bingham, K Khaw. (2010) The Short-Form Six-Dimension utility index predicted mortality in the {Europe}an Prospective Investigation into Cancer-Norfolk prospective population-based study. J Clin Epidemiol 63 (2):192-198.

LpPLA2SC, T Alexander, Gao Pei, O Lia, W Sarah, A Emanuele, K Stephen, B Christie, CP Christopher, C Michael, C Mary, H Albert, P Chris, TG Simon, C Rory, D John. (2010) Lipoprotein-associated phospholipase A(2) and risk of coronary disease, stroke, and mortality: collaborative analysis of 32 prospective studies. Lancet 375 (9725):1536-1544.

ERFC, S N., G P., K S., G R., K S., A E., I E., L D., S E., S M., S C., L S., P L., T A., S N., W I., R K., D J.. (2010) Diabetes mellitus, fasting blood glucose concentration, and risk of vascular disease: a collaborative meta-analysis of 102 prospective studies. Lancet 375 (9733):2215-2222.

KM Ikram, X Sim, Sim Xueling, RA Jensen, M Cotch, AW Hewitt, AM Ikram, J Wang, R Klein, BEK Klein, MMB Breteler, N Cheung, G Liew, P Mitchell, AG Uitterlinden, F Rivadeneira, A Hofman, PTVM Jong, CM van Duijn, L Kao, C Cheng, A Smith, NL Glazer, T Lumley, B McKnight, BM Psaty, F Jonasson, G Eiriksdottir, T Aspelund, G Consortium, TB Harris, LJ Launer, KD Taylor, Li Xiaohui, SK Iyengar, Xi Quansheng, TA Sivakumaran, DA Mackey, S Macgregor, NG Martin, TL Young, JC Bis, KL Wiggins, SR Heckbert, CJ Hammond, T Andrew, S Fahy, J Attia, EG Holliday, RJ Scott, AFM Islam, JI Rotter, AK McAuley, E Boerwinkle, SE Tai, V Gudnason, DS Siscovick, JR Vingerling, TY Wong. (2010) Four novel Loci (19q13, 6q24, 12q24, and 5q14) influence the microcirculation in vivo. PLoS Genet 6 (10):e1001184.

RN Freitas, K Khaw, Wu Kelvin, R Bowman, H Jeffery, R Luben, NJ Wareham, SA Bingham. (2009) A HMGCR polymorphism is associated with relations between blood pressure and urinary sodium and potassium ratio in the Epic-Norfolk Study. J Am Soc Hypertens 3 (4):238-244.

BJ Arsenault, I Lemieux, J Despres, P Gagnon, NJ Wareham, ESG Stroes, JJP Kastelein, K Khaw, MS Boekholdt. (2009) {HDL} particle size and the risk of coronary heart disease in apparently healthy men and women: The EPIC-Norfolk prospective population study. Atherosclerosis ():.

BJ Arsenault, JS Rana, ESG Stroes, J Despres, PK Shah, JJP Kastelein, NJ Wareham, MS Boekholdt, K Khaw. (2009) Beyond Low-Density Lipoprotein Cholesterol Respective Contributions of Non-High-Density Lipoprotein Cholesterol Levels, Triglycerides, and the Total Cholesterol/High-Density Lipoprotein Cholesterol Ratio to Coronary Heart Disease Risk in Apparently Healthy Men and Women. J Am Coll Cardiol 55 (1):35-41.

H Ward, PN Mitrou, R Bowman, R Luben, NJ Wareham, K Khaw, S Bingham. (2009) APOE genotype, lipids, and coronary heart disease risk: a prospective population study. Arch Intern Med 169 (15):1424-1429.

PK Myint, RN Luben, NJ Wareham, SA Bingham, K Khaw. (2009) Combined effect of health behaviours and risk of first ever stroke in 20,040~{m}en and women over 11 years' follow-up in Norfolk cohort of {Europe}an Prospective Investigation of Cancer (EPIC Norfolk): prospective population study. BMJ 338 ():b349.

C Newton-Cheh, T Johnson, V Gateva, MD Tobin, M Bochud, L Coin, SS Najjar, J Zhao, SC Heath, S Eyheramendy, K Papadakis, BF Voight, LJ Scott, F Zhang, M Farrall, T Tanaka, C Wallace, JC Chambers, K Khaw, P Nilsson, Pim van der Harst, S Polidoro, DE Grobbee, CN Onland-Moret, ML Bots, LV Wain, KS Elliott, A Teumer, J Luan, G Lucas, J Kuusisto, PR Burton, D Hadley, WL McArdle, Trust Wellcome, M Brown, A Dominiczak, SJ Newhouse, NJ Samani, J Webster, E Zeggini, JS Beckmann, S Bergmann, N Lim, K Song, P Vollenweider, G Waeber, DM Waterworth, Xin Yuan, L Groop, M Orho-Melander, A Allione, A Gregorio, S Guarrera, S Panico, F Ricceri, V Romanazzi, C Sacerdote, P Vineis, I Barroso, MS Sandhu, RN Luben, GJ Crawford, P Jousilahti, M Perola, M Boehnke, LL Bonnycastle, FS Collins, AU Jackson, KL Mohlke, HM Stringham, TT Valle, CJ Willer, RN Bergman, MA Morken, A Doring, C Gieger, T Illig, T Meitinger, E Org, A Pfeufer, EH Wichmann, S Kathiresan, J Marrugat, CJ ODonnell, SM Schwartz, DS Siscovick, I Subirana, NB Freimer, A Hartikainen, MI McCarthy, PF OReilly, L Peltonen, A Pouta, PE Jong, H Snieder, WH van Gilst, R Clarke, A Goel, A Hamsten, JF Peden, Udo Seedorf, A Syvanen, G Tognoni, EG Lakatta, S Sanna, P Scheet, D Schlessinger, A Scuteri, M Dorr, F Ernst, SB Felix, G Homuth, R Lorbeer, T Reffelmann, R Rettig, Uwe Volker, P Galan, Ivo Gut, S Hercberg, MG Lathrop, D Zelenika, P Deloukas, N Soranzo, FM Williams, G Zhai, V Salomaa, M Laakso, R Elosua, NG Forouhi, H Volzke, CS Uiterwaal, YT van der Schouw, ME Numans, G Matullo, G Navis, G Berglund, SA Bingham, JS Kooner, JM Connell, S Bandinelli, L Ferrucci, H Watkins, Tim Spector, J Tuomilehto, D Altshuler, DP Strachan, M Laan, P Meneton, NJ Wareham, M Uda, M Jarvelin, V Mooser, O Melander, R Loos, P Elliott, GR Abecasis, M Caulfield, PB Munroe. (2009) Genome-wide association study identifies eight loci associated with blood pressure. Nat Genet ():.

E McFadden, R Luben, N Wareham, S Bingham, K Khaw. (2009) Social Class, Risk Factors, and Stroke Incidence in Men and Women. A Prospective Study in the {Europe}an Prospective Investigation Into Cancer in Norfolk Cohort. Stroke ():.

EC McFadden, RN Luben, SA Bingham, NJ Wareham, A Kinmonth, K Khaw. (2009) Self-rated health does not explain the socioeconomic differential in mortality: A prospective study in the {Europe}an Prospective Investigation of Cancer and Nutrition in Norfolk (EPIC-Norfolk) cohort. J Epidemiol Community Health ():.

Z Mallat, T Simon, J Benessiano, K Clement, S Taleb, NJ Wareham, R Luben, K Khaw, A Tedgui, MS Boekholdt. (2009) Retinol-binding protein 4 and prediction of incident coronary events in healthy men and women. J Clin Endocrinol Metab 94 (1):255-260.

R Lakshman, NG Forouhi, SJ Sharp, R Luben, SA Bingham, K Khaw, NJ Wareham, Ken Ong. (2009) Early age at menarche associated with cardiovascular disease and mortality. J Clin Endocrinol Metab 94 (12):4953-4960.

RK Simmons, S Sharp, MS Boekholdt, LA Sargeant, K Khaw, NJ Wareham, SJ Griffin. (2008) Evaluation of the Framingham risk score in the {Europe}an Prospective Investigation of Cancer-Norfolk cohort: does adding glycated hemoglobin improve the prediction of coronary heart disease events? Arch Intern Med 168 (11):1209-1216.

PG Surtees, NWJ Wainwright, RN Luben, NJ Wareham, SA Bingham, K Khaw. (2008) Depression and ischemic heart disease mortality: evidence from the EPIC-Norfolk {United Kingdom} prospective cohort study. Am J Psychiatry 165 (4):515-523.

PG Surtees, NWJ Wainwright, RN Luben, NJ Wareham, SA Bingham, KT Khaw. (2008) Psychological distress, major depressive disorder, and risk of stroke. Neurology 70 (10):788-794.

S Sinha, PK Myint, RN Luben, K Khaw. (2008) Accuracy of death certification and hospital record linkage for identification of incident stroke. BMC Med Res Methodol 8 ():74.

S Weikert, H Boeing, T Pischon, C Weikert, A Olsen, A Tjonneland, Kim Overvad, N Becker, J Linseisen, A Trichopoulou, T Mountokalakis, D Trichopoulos, S Sieri, D Palli, P Vineis, S Panico, PHM Peeters, Bueno-de-Mesquita Bas, MWM Verschuren, B Ljungberg, G Hallmans, G Berglund, CA Gonzalez, M Dorronsoro, A Barricarte, MJ Tormo, N Allen, A Roddam, S Bingham, K Khaw, S Rinaldi, P Ferrari, T Norat, E Riboli. (2008) Blood pressure and risk of renal cell carcinoma in the {Europe}an prospective investigation into cancer and nutrition. Am J Epidemiol 167 (4):438-446.

AA Welch, A Mulligan, SA Bingham, K Khaw. (2008) Urine pH is an indicator of dietary acid-base load, fruit and vegetables and meat intakes: results from the {Europe}an Prospective Investigation into Cancer and Nutrition (EPIC)-Norfolk population study. Br J Nutr 99 (6):1335-1343.

PG Surtees, NWJ Wainwright, MS Boekholdt, RN Luben, NJ Wareham, K Khaw. (2008) Major Depression, C-Reactive Protein, and Incident Ischemic Heart Disease in Healthy Men and Women. Psychosom Med ():.

PK Myint, RN Luben, AA Welch, SA Bingham, NJ Wareham, K Khaw. (2008) Plasma vitamin C concentrations predict risk of incident stroke over 10 y in 20 649 participants of the {Europe}an Prospective Investigation into Cancer Norfolk prospective population study. Am J Clin Nutr 87 (1):64-69.

T Norat, R Bowman, R Luben, A Welch, K Khaw, N Wareham, S Bingham. (2008) Blood pressure and interactions between the angiotensin polymorphism AGT M235{T} and sodium intake: a cross-sectional population study. Am J Clin Nutr 88 (2):392-397.

P Myint, S Sinha, R Luben, S Bingham, N Wareham, K Khaw. (2008) Risk factors for first-ever stroke in the EPIC-Norfolk prospective population-based study. Eur J Cardiovasc Prev Rehabil ():.

E McFadden, R Luben, N Wareham, S Bingham, K Khaw. (2008) Occupational social class, risk factors and cardiovascular disease incidence in men and women: a prospective study in the {Europe}an Prospective Investigation of Cancer and Nutrition in Norfolk (EPIC-Norfolk) cohort. Eur J Epidemiol 23 (7):449-458.

RS Birjmohun, GM Dallinga-Thie, J Kuivenhoven, ESG Stroes, JD Otvos, NJ Wareham, R Luben, JJP Kastelein, K Khaw, MS Boekholdt. (2007) Apolipoprotein A-II is inversely associated with risk of future coronary artery disease. Circulation 116 (18):2029-2035.

N Sarwar, J Danesh, G Eiriksdottir, G Sigurdsson, N Wareham, S Bingham, MS Boekholdt, K Khaw, V Gudnason. (2007) Triglycerides and the risk of coronary heart disease: 10,158 incident cases among 262,525 participants in 29~{W}estern prospective studies. Circulation 115 (4):450-458.

PK Myint, RN Luben, PG Surtees, NWJ Wainwright, AA Welch, SA Bingham, NJ Wareham, RD Smith, Ian Harvey, K Khaw. (2007) Self-reported mental health-related quality of life and mortality in men and women in the {Europe}an Prospective Investigation into Cancer (EPIC-Norfolk): a prospective population study. Psychosom Med 69 (5):410-414.

PK Myint, S Sinha, NJ Wareham, SA Bingham, RN Luben, AA Welch, K Khaw. (2007) Glycated hemoglobin and risk of stroke in people without known diabetes in the {Europe}an Prospective Investigation into Cancer (EPIC)-Norfolk prospective population study: a threshold relationship? Stroke 38 (2):271-275.

PK Myint, PG Surtees, NWJ Wainwright, RN Luben, AA Welch, SA Bingham, NJ Wareham, KT Khaw. (2007) Physical health-related quality of life predicts stroke in the EPIC-Norfolk. Neurology 69 (24):2243-2248.

MC Meuwese, ESG Stroes, SL Hazen, JN van Miert, J Kuivenhoven, RG Schaub, NJ Wareham, R Luben, JJP Kastelein, K Khaw, MS Boekholdt. (2007) Serum myeloperoxidase levels are associated with the future risk of coronary artery disease in apparently healthy individuals: the EPIC-Norfolk Prospective Population Study. J Am Coll Cardiol 50 (2):159-165.

K Khaw, M Dowsett, E Folkerd, S Bingham, N Wareham, R Luben, A Welch, N Day. (2007) Endogenous testosterone and mortality due to all causes, cardiovascular disease, and cancer in men: {Europe}an prospective investigation into cancer in Norfolk (EPIC-Norfolk) Prospective Population Study. Circulation 116 (23):2694-2701.

J Danesh, R Saracci, G Berglund, E Feskens, Kim Overvad, S Panico, S Thompson, A Fournier, F Clavel-Chapelon, M Canonico, R Kaaks, J Linseisen, H Boeing, T Pischon, C Weikert, A Olsen, A Tjonneland, S Johnsen, M Jensen, JR Quiros, Alberto Carlos, M Perez, N Larranaga, C Sanchez, C Iribas, S Bingham, K Khaw, N Wareham, T Key, A Roddam, A Trichopoulou, V Benetou, D Trichopoulos, G Masala, S Sieri, R Tumino, C Sacerdote, A Mattiello, MWM Verschuren, Bueno-de-Mesquita Bas, DE Grobbee, YT van der Schouw, O Melander, G Hallmans, P Wennberg, E Lund, M Kumle, G Skeie, P Ferrari, N Slimani, T Norat, E Riboli, E C-Heart. (2007) EPIC-Heart: the cardiovascular component of a prospective study of nutritional, lifestyle and biological factors in 520,000~{m}iddle-aged participants from 10 {Europe}an countries. Eur J Epidemiol 22 (2):129-141.

K Khaw, N Wareham. (2006) Glycated hemoglobin as a marker of cardiovascular risk. Curr Opin Lipidol 17 (6):637-643.

MS Boekholdt, MS Sandhu, NE Day, R Luben, SA Bingham, Ron Peters, NJ Wareham, K Khaw. (2006) Physical activity, C-reactive protein levels and the risk of future coronary artery disease in apparently healthy men and women: the EPIC-Norfolk prospective population study. Eur J Cardiovasc Prev Rehabil 13 (6):970-976.

MS Boekholdt, MC Meuwese, NE Day, R Luben, A Welch, NJ Wareham, K Khaw. (2006) Plasma concentrations of ascorbic acid and C-reactive protein, and risk of future coronary artery disease, in apparently healthy men and women: the EPIC-Norfolk prospective population study. Br J Nutr 96 (3):516-522.

R Antonelli-Incalzi, C Pedone, MM McDermott, S Bandinelli, B Miniati, R Lova, F Lauretani, L Ferrucci. (2006) Association between nutrient intake and peripheral artery disease: results from the InCHIANTI study. Atherosclerosis 186 (1):200-206.

FJB van Duijnhoven, CH van Gils, ID Bezemer, PHM Peeters, YT van der Schouw, DE Grobbee. (2006) Use of hormones in the menopausal transition period in the {Netherlands} between 1993 and 1997. Maturitas 53 (4):462-475.

J Rip, MC Nierman, NJ Wareham, R Luben, SA Bingham, NE Day, JNI van Miert, BA Hutten, JJP Kastelein, J Kuivenhoven, K Khaw, MS Boekholdt. (2006) Serum lipoprotein lipase concentration and risk for future coronary artery disease: the EPIC-Norfolk prospective population study. Arterioscler Thromb Vasc Biol 26 (3):637-642.

V Pala, S Sieri, G Masala, D Palli, S Panico, P Vineis, C Sacerdote, A Mattiello, R Galasso, S Salvini, M Ceroti, F Berrino, E Fusconi, R Tumino, G Frasca, E Riboli, A Trichopoulou, N Baibas, V Krogh. (2006) Associations between dietary pattern and lifestyle, anthropometry and other health indicators in the elderly participants of the EPIC-{Italy} cohort. Nutr Metab Cardiovasc Dis 16 (3):186-201.

PK Myint, RN Luben, PG Surtees, NWJ Wainwright, AA Welch, SA Bingham, NE Day, NJ Wareham, K Khaw. (2006) Relation between self-reported physical functional health and chronic disease mortality in men and women in the {Europe}an Prospective Investigation into Cancer (EPIC-Norfolk): a prospective population study. Ann Epidemiol 16 (6):492-500.

PK Myint, RN Luben, NJ Wareham, AA Welch, SA Bingham, NE Day, K Khaw. (2006) Combined work and leisure physical activity and risk of stroke in men and women in the {Europe}an prospective investigation into Cancer-Norfolk Prospective Population Study. Neuroepidemiology 27 (3):122-129.

PK Myint, RN Luben, AA Welch, SA Bingham, NJ Wareham, K Khaw. (2006) Effect of age on the relationship of occupational social class with prevalence of modifiable cardiovascular risk factors and cardiovascular diseases. A population-based cross-sectional study from {Europe}an Prospective Investigation into Cancer - Norfolk (EPIC-Norfolk). Gerontology 52 (1):51-58.

PK Myint, AA Welch, SA Bingham, RN Luben, NJ Wareham, NE Day, K Khaw. (2006) Habitual fish consumption and risk of incident stroke: the {Europe}an Prospective Investigation into Cancer (EPIC)-Norfolk prospective population study. Public Health Nutr 9 (7):882-888.

PK Myint, AA Welch, SA Bingham, RN Luben, NJ Wareham, NE Day, K Khaw. (2006) Smoking predicts long-term mortality in stroke: The {Europe}an Prospective Investigation into Cancer (EPIC)-Norfolk prospective population study. Prev Med 42 (2):128-131.

TT Keller, D Choi, C Nagel, H Velthuis, VEA Gerdes, NJ Wareham, SA Bingham, R Luben, CE Hack, PH Reitsma, M Levi, KT Khaw, SM Boekholdt. (2006) Tissue factor serum levels and the risk of future coronary artery disease in apparently healthy men and women: the EPIC-Norfolk prospective population study. J Thromb Haemost 4 (11):2391-2396.

M Kataoka, R Warren, R Luben, J Camus, E Denton, E Sala, N Day, K Khaw. (2006) How predictive is breast arterial calcification of cardiovascular disease and risk factors when found at screening mammography? AJR Am J Roentgenol 187 (1):73-80.

K Hoffmann, C Heidemann, C Weikert, MB Schulze, H Boeing. (2006) Estimating the proportion of disease due to classes of sufficient causes. Am J Epidemiol 163 (1):76-83.

K Khaw, R Jakes, S Bingham, A Welch, R Luben, N Day, N Wareham. (2006) Work and leisure time physical activity assessed using a simple, pragmatic, validated questionnaire and incident cardiovascular disease and all-cause mortality in men and women: The {Europe}an Prospective Investigation into Cancer in Norfolk prospective population study. Int J Epidemiol 35 (4):1034-1043.

MS Boekholdt, TT Keller, NJ Wareham, R Luben, SA Bingham, NE Day, MS Sandhu, WJ Jukema, JJP Kastelein, EC Hack, K Khaw. (2005) Serum levels of type II secretory phospholipase A2 and the risk of future coronary artery disease in apparently healthy men and women: the EPIC-Norfolk Prospective Population Study. Arterioscler Thromb Vasc Biol 25 (4):839-846.

M Schulz, AD Liese, H Boeing, JE Cunningham, CG Moore, A Kroke. (2005) Associations of short-term weight changes and weight cycling with incidence of essential hypertension in the EPIC-Potsdam Study. J Hum Hypertens 19 (1):61-67.

MF Yuyun, K Khaw, R Luben, A Welch, S Bingham, NE Day, NJ Wareham. (2004) Microalbuminuria, cardiovascular risk factors and cardiovascular morbidity in a British population: the EPIC-Norfolk population-based study. Eur J Cardiovasc Prev Rehabil 11 (3):207-213.

MF Yuyun, K Khaw, R Luben, A Welch, S Bingham, NE Day, NJ Wareham, Prospective European. (2004) Microalbuminuria independently predicts all-cause and cardiovascular mortality in a British population: The {Europe}an Prospective Investigation into Cancer in Norfolk (EPIC-Norfolk) population study. Int J Epidemiol 33 (1):189-198.

ABM Wilmink, AA Welch, CRG Quick, PJ Burns, CS Hubbard, AW Bradbury, NE Day. (2004) Dietary folate and vitamin B6 are independent predictors of peripheral arterial occlusive disease. J Vasc Surg 39 (3):513-516.

T Psaltopoulou, A Naska, P Orfanos, D Trichopoulos, T Mountokalakis, A Trichopoulou. (2004) Olive oil, the Mediterranean diet, and arterial blood pressure: the Greek {Europe}an Prospective Investigation into Cancer and Nutrition (EPIC) study. Am J Clin Nutr 80 (4):1012-1018.

T Psaltopoulou, P Orfanos, A Naska, D Lenas, D Trichopoulos, A Trichopoulou. (2004) Prevalence, awareness, treatment and control of hypertension in a general population sample of 26,913 adults in the Greek EPIC study. Int J Epidemiol 33 (6):1345-1352.

G Nagel, D Zoller, T Wiedmann, U Bussas, El Idrissi-Lamghari, J Kneisel, WU Batzler, N Becker. (2004) [The use of the Epidemiology Cancer registry Baden-W{\"{u}}rttemberg in the follow-up of the EPIC cohort]. Gesundheitswesen 66 (8-9):469-474.

K Khaw, S Bingham, A Welch, R Luben, E OBrien, N Wareham, N Day. (2004) Blood pressure and urinary sodium in men and women: the Norfolk Cohort of the {Europe}an Prospective Investigation into Cancer (EPIC-Norfolk). Am J Clin Nutr 80 (5):1397-1403.

K Khaw, N Wareham, S Bingham, R Luben, A Welch, N Day. (2004) Association of hemoglobin A1c with cardiovascular disease and mortality in adults: the {Europe}an prospective investigation into cancer in Norfolk. Ann Intern Med 141 (6):413-420.

NJ Goodson, AJ Silman, DJ Pattison, M Lunt, D Bunn, R Luben, N Day, KT Khaw, DPM Symmons. (2004) Traditional cardiovascular risk factors measured prior to the onset of inflammatory polyarthritis. Rheumatology (Oxford) 43 (6):731-736.

D Canoy, R Luben, A Welch, S Bingham, N Wareham, N Day, K Khaw. (2004) Fat distribution, body mass index and blood pressure in 22,090~{m}en and women in the Norfolk cohort of the {Europe}an Prospective Investigation into Cancer and Nutrition (EPIC-Norfolk) study. J Hypertens 22 (11):2067-2074.

MM Bergmann, EJ Jacobs, K Hoffmann, H Boeing. (2004) Agreement of self-reported medical history: comparison of an in-person interview with a self-administered questionnaire. Eur J Epidemiol 19 (5):411-416.

MS Boekholdt, J Kuivenhoven, NJ Wareham, Ron Peters, WJ Jukema, R Luben, SA Bingham, NE Day, JJP Kastelein, K Khaw. (2004) Plasma levels of cholesteryl ester transfer protein and the risk of future coronary artery disease in apparently healthy men and women: the prospective EPIC ({Europe}an Prospective Investigation into Cancer and nutrition)-Norfolk population study. Circulation 110 (11):1418-1423.

MS Boekholdt, Ron Peters, EC Hack, NE Day, R Luben, SA Bingham, NJ Wareham, PH Reitsma, K Khaw. (2004) IL-8 plasma concentrations and the risk of future coronary artery disease in apparently healthy men and women: the EPIC-Norfolk prospective population study. Arterioscler Thromb Vasc Biol 24 (8):1503-1508.

MS Boekholdt, Ron Peters, NE Day, R Luben, SA Bingham, NJ Wareham, EC Hack, PH Reitsma, K Khaw. (2004) Macrophage migration inhibitory factor and the risk of myocardial infarction or death due to coronary artery disease in adults without prior myocardial infarction or stroke: the EPIC-Norfolk Prospective Population study. Am J Med 117 (6):390-397.

P Surtees, N Wainwright, R Luben, K Khaw, N Day. (2003) Sense of coherence and mortality in men and women in the EPIC-Norfolk {United Kingdom} prospective cohort study. Am J Epidemiol 158 (12):1202-1209.

MB Schulze, K Hoffmann, A Kroke, H Boeing. (2003) Risk of hypertension among women in the EPIC-Potsdam Study: comparison of relative risk estimates for exploratory and hypothesis-oriented dietary patterns. Am J Epidemiol 158 (4):365-373.

RW Jakes, NE Day, KT Khaw, R Luben, S Oakes, A Welch, S Bingham, NJ Wareham. (2003) Television viewing and low participation in vigorous recreation are independently associated with obesity and markers of cardiovascular disease risk: EPIC-Norfolk population-based study. Eur J Clin Nutr 57 (9):1089-1096.

MB Schulze, A Kroke, R Saracci, H Boeing. (2002) The effect of differences in measurement procedure on the comparability of blood pressure estimates in multi-centre studies. Blood Press Monit 7 (2):95-104.

PN Appleby, GK Davey, TJ Key. (2002) Hypertension and blood pressure among meat eaters, fish eaters, vegetarians and vegans in EPIC-Oxford. Public Health Nutr 5 (5):645-654.

SM Titan, S Bingham, A Welch, R Luben, S Oakes, N Day, KT Khaw. (2001) Frequency of eating and concentrations of serum cholesterol in the Norfolk population of the {Europe}an prospective investigation into cancer (EPIC-Norfolk): cross sectional study. BMJ 323 (7324):1286-1288.

KT Khaw, S Bingham, A Welch, R Luben, N Wareham, S Oakes, N Day. (2001) Relation between plasma ascorbic acid and mortality in men and women in EPIC-Norfolk prospective study: a prospective population study. {Europe}an Prospective Investigation into Cancer and Nutrition. Lancet 357 (9257):657-663.

KT Khaw, N Wareham, R Luben, S Bingham, S Oakes, A Welch, N Day. (2001) Glycated haemoglobin, diabetes, and mortality in men in Norfolk cohort of european prospective investigation of cancer and nutrition (EPIC-Norfolk). BMJ 322 (7277):15-18.

MB Schulze, A Kroke, MM Bergmann, H Boeing. (2000) Differences of blood pressure estimates between consecutive measurements on one occasion: implications for inter-study comparability of epidemiologic studies. Eur J Epidemiol 16 (10):891-898.

MJ Tormo, C Navarro, MD Chirlaque, X Barber, Spain. Group. (2000) Is there a different dietetic pattern depending on self-knowledge of high blood pressure? Eur J Epidemiol 16 (10):963-971.

A Kroke, MM Bergmann, G Lotze, A Jeckel, K Klipstein-Grobusch, H Boeing. (1999) Measures of quality control in the German component of the EPIC study. {Europe}an Prospective Investigation into Cancer and Nutrition. Ann Nutr Metab 43 (4):216-224.

A Kroke, W Fleischhauer, S Mieke, K Klipstein-Grobusch, SN Willich, H Boeing. (1998) Blood pressure measurement in epidemiological studies: a comparative analysis of two methods. Data from the EPIC-Potsdam Study. {Europe}an Prospective Investigation into Cancer and Nutrition. J Hypertens 16 (6):739-746.

A Kroke, M Bergmann, K Klipstein-Grobusch, H Boeing. (1998) Obesity, body fat distribution and body build: their relation to blood pressure and prevalence of hypertension. Int J Obes Relat Metab Disord 22 (11):1062-1070.

MA Pols, PH Peeters, JW Twisk, HC Kemper, DE Grobbee. (1997) Physical activity and cardiovascular disease risk profile in women. Am J Epidemiol 146 (4):322-328.

AR Ness, KT Khaw, S Bingham, NE Day. (1996) Vitamin C status and blood pressure. J Hypertens 14 (4):503-508.

S Panico. (1992) [Prospective studies based on biological specimen banks: a new epidemiological generation]. Ann Ist Super Sanita 28 (3):365-369.

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